Lec 1 Otomo-Corgel Flashcards

1
Q

waht is the driving force bhind all major age related disorders

A

inflammation

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2
Q

3 aspects of apathogenesis of peridontal disease have a role and impact on the system inflamamtory immune response

A
  1. infection , inflamm, adaptive immunity
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3
Q

true or false

pt has pd inflamma and pt has diabetes more likely to have pd 1:2

A

true

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4
Q

probing upon bleeding is a sign that their is inflamamtion without a lot of eitolgoical factors, what may they have

A

systemic disease, diabetes

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5
Q

Hx with diabetes, what are you looking for first?

A

level of control of the disease, diabetes

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6
Q

true or false

diabetes type i and Ii incrase the risk fere severe pd?

  1. the earlier onset of diabetes youll have pd?
A

true

true

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7
Q

____ is a signfiicant predictor for pd independent of the effects of smoking ,age, race, ethnicity, and smoking

A

obesity

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8
Q

waht % of US Pop are overeight? and __ fold chance of becoming diabetic and __ fold risk of pd

A

60

10

3

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9
Q

____ tissues produce actue phase proteins or cytokines proportional to its mass in circulation

A

adipose

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10
Q

___ and __ contribute to the systemic hyperinflammtion increase in hyperlidemia, and increase in insulin resistance

A

IL 6 and tumur necrosis factor alpha

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11
Q

incluence of glycemic control

diabetic pt with severe pd had a ___ times woresening of glycemic congtrol over 2 years

A

6x

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12
Q

Perio tx reducing inflamamtion can it improve glycemic control?

A

probably

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13
Q

HB1ac is?

A

measure life of the Hb attached to the rbc and gives you the overall control of the diabetes

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14
Q

___ associted with imparied glucose tolerance in non diabetics

A

deeper the pockets

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15
Q

true or false

longer the pt have infection and severe longer it takes for response of therapy, not happen overnight, may be 6 - 7 months?

A

depends still a controversy

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16
Q

true or false

well controlled diabetic pt have simialr pd status as controlled non diabetic group

A

true

17
Q

waht altered vascualr physiology would you ahve with diabetes and pd

A

delayed wound healing

18
Q

diabetes and pd pt: collagen metabolism ___ and congenase activitty___

A

decreased

increased

19
Q

most common medical emergency?

A

hypoglycemic crisis

20
Q

1 cause of kidney failure is ?

A

diabetes

21
Q

what incidence does pts with diabetes have with nephopathy?

A

2x - 2.6x

22
Q

____ periodontal therapy reduces in HbA1C at 3 months by what percent?

A

mechanical

0.4% [may be good enough to put pt off of insulin]

23
Q

what is the strongest systemic disease with periodontal disease?

A

diabetes

24
Q

when you think of association which type of severity do you think of?

A

moderate to severe pd

chronic long term inflammation

25
Q

______ studies showed that patients had better ____ flow its not short term therapy but long term therapy

A

tenelli

brachial

26
Q

what specific bacteria in their corotic vessle had severe pd dissease?

A

porphomous gingivallis

27
Q

if P gingivalis is in the blood stream they will be a sticky bug nd form a _____ plaque bc rbc love this bac

A

micromophological plaque and this clots the blood

28
Q

know: pd DOES NOT CAUSE caridovascualr disase

diabetes does not cause pd

if you ahve pd incrase risk if you ahve genetic sus, smoker, and its all a balance and every pt is an indiv

A

know: pd DOES NOT CAUSE caridovascualr disase

diabetes does not cause pd

if you ahve pd incrase risk if you ahve genetic sus, smoker, and its all a balance and every pt is an indiv

29
Q

inflammatiory markers and pd:

hs - c reactive protein does what?

A

measures level of inflamma

30
Q

which is a better inflammatory marker hs crp or cholesterol?

A

hs crp

31
Q

p gingivalis have been found in cerebral vessles and the associatation with ___ is stronger than the assocation with MI

A

stroke

32
Q

Periodontal pathogens can cause _______

A

atherosclerosis

33
Q

if there is no risk, then why premedicate this heart vlave pt [possibly with murmur]

A

premed the pt bc its up to the clinician for which meds the pt takes and its up to the pt to take them

34
Q

women with advanced pd have ___ more likely to have pre mature babies?

A

7x

35
Q

if pt tells you she wants to be pregnant, you ahve to do a ____ therpy and if she has bleeding upon probing you need to treat this _____ conception?

A

total

before

36
Q

treat preg pt before the ____ trimester

A

1st

37
Q

_____ and ____ higher in advacned pd pt

A

pneumonia and aspiration

38
Q
A