lec 1- intro Flashcards
1
Q
what caused sheep embryos to form one eye?
A
a chemical in corn lilies called cyclopamine
2
Q
how did cyclopamine cause one eyed sheep?
A
cyclopamine interfered with hedgehog gene activity, causing the expression of one eye due to it inhibiting the signalling pathway
3
Q
what are hedgehog genes?
A
genes that are used in signalling cell growth and development
4
Q
can an increased concentration in hedgehog gene cause increased toes in kitten?
A
yes
5
Q
how does hedgehog genes cause cancer?
A
in places it should be off, it is still expressed, causing cell growth and cancer
6
Q
do multiple cancer drugs stop the hedgehog genes to stop cancer?
A
yes
