Lec 1 Flashcards
What is the telomere and cosist of what
Where it found
Function
Specialized DNA cap
Consist of a hundred or thousands of repeated of the same short DNA 🧬 sequence which varies between organisms but is 5 TTAGGG3 in humans
Present in the tip of eukaryotic chromosome
Telomere act as a cap that protect internal region of chromosomes and they worn down a small amount in each round of dna replication
Telomeres
Does the length of telomere effect
Protein dna complexes that cap ends of eukaryotic chromosome
Maintenance of the length of the telomeres is essential for genomic stability and cell viability
Telomere shortening correlate with
Majority of cancer cells depend on
Cellular aging
Activation of telomerase to gain proliferative immortality
Telomerase
An enzyme that extend the telomeres of chromosome is an RNA DEPENDENT DNA POLYMERASE meaning an enzyme that can make dna 🧬 using RNA as a template