Lec 03: Morphology of Non-Neoplastic Lymph Nodes Flashcards
Which lymph node region corresponds to humoral response?
a. Cortex
b. Paracortex
c. Capsule
d. Medulla
a. Cortex
For humoral response.
Correct lymphatic flow:
a. Medulla -> Paracortex -> Cortex
b. Cortex -> Paracortex -> Medulla
c. Cortex -> Medulla -> Paracortex
d. Paracortex -> Medulla -> Paracortex
b. Cortex -> Paracortex -> Medulla
* Traced from afferent lymphatics going into the node to efferent lymphatics going outside.
Lymph node part which predominates most of the cortex.
Follicles.
PRIMARY or SECONDARY lymphoid follicle: composed of inactive lymphocytes.
PRIMARY lymphoid follicle.
They appear homogenous because it is composed of INACTIVE LYMPHOCYTES which have not encountered an antigen yet.
PRIMARY or SECONDARY lymphoid follicle: heterogenous in appearance.
SECONDARY lymphoid follicle.
Appear heterogenous because it is composed of stimulated lymphocytes.
PRIMARY or SECONDARY lymphoid follicle: found mostly in adults.
SECONDARY lymphoid follicle.
TRUE or FALSE: The mantle zone of the lymph node cortex contains B cells ONLY.
TRUE.
The B cells also “fence around the follicle.”
CENTROBLAST or CENTROCYTE?
: Immature
CENTROBLAST
CENTROBLAST or CENTROCYTE?
: Darker & smaller because they haven’t encountered antigens yet.
CENTROBLAST
CENTROBLAST or CENTROCYTE?
: Contain macrophages
CENTROCYTE
They have encountered antigens/
CENTROBLAST or CENTROCYTE?
: More cytoplasm
CENTROCYTE
These cells form a meshwork of follicles.
Follicular Dendritic Cells (FDC)
AKA interfollicular region/area:
a. Cortex
b. Paracortex
c. Capsule
d. Medulla
b. Paracortex
It is located beneath the cortex and BETWEEN the lymphoid follicles.
Contains the mobile pool of T-cells.
a. Cortex
b. Paracortex
c. Capsule
d. Medulla
b. Paracortex
Presence of post-capillary venules (to enter central circulation) lined by endothelial cells (also active in immune response) and characterized by presence of lymphocytes in
the wall.
a. Cortex
b. Paracortex
c. Capsule
d. Medulla
b. Paracortex