Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

[OS 216] Exam 2 Trans Cluster 1 > Lec 01: Allergic Rhinitis and Bronchial Asthma > Flashcards

Lec 01: Allergic Rhinitis and Bronchial Asthma Flashcards

1
Q

Which antibody is involved in allergic rhinitis?

A

IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is allergic rhinitis?

A

a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

(T/F) Allergic rhinitis more commonly affects male adults.

A

F. adulthood prevalence: males = females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

(T/F) Allergic rhinitis more commonly affects male children.

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the main signs and symptoms of allergic rhinitis?

A
  1. Rhinorrhea
  2. Nasal obstruction and congestion
  3. Nasal itching/pruritus
  4. Sneezing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the Ssx of clear rhinorrhea?

A

chronic postnasal drip, cobblestone throat, frequent throat clearing, itchy throat, non-productive cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the Ssx of nasal congestion?

A

allergic shiners, pale turbinates, mouth breathing, abnormal facial development, dental malocclusion, snoring, sleep disturbance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the Ssx of nasal itching?

A

facial grimace, allergic salute, nasal crease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which of the following is false about Dennie-Morgan lines?
A. also known as panda eyes
B. marker for allergy
C. occurs in people with good capillary refill around the eyes
D. occurs in people with frequent nasal congestion

A

C.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

(T/F) The previous classification of allergic rhinitis was based on the time of exposure.

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
Which of the following is not a classification of AR based on the time of exposure?
A. perennial
B. occasional
C. seasonal
D. occupational
A

B.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the bases of the ARIA classification?

A
  1. frequency of occurence

2. severity of symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

(T/F) AR is considered to have an intermittent frequency when it occurs two days in a week for 3 weeks.

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the criteria used to determine the severity of AR?

A

sleep pattern, impairment of daily activities, functioning at work/school, “troublesome” symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

(T/F) Allergic rhinitis is a type 2 hypersensitivity reaction.

A

F

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the two phases of a type 1 hypersensitivity reaction?

A

sensitization phase/elicitation phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

(T/F) IL-4 is secreted by TH2 cells.

A

T

18
Q

What substances are released during mast cell degranulation?

A

histamine, leukotrienes, cytokines

19
Q

Which of the three (histamine, leukotrienes, cytokines) is primarily responsible for a late-phase reaction?

A

cytokines

20
Q

(T/F) A late phase reaction may occur several hours after initial exposure to antigen but requires additional exposure.

A

F

21
Q

What are the risk factors for allergic rhinitis?

A

increasing age, atopy, higher socioeconomic class, family history, positive allergy skin test, pollution, tobacco smoke/indoor allergens, early introduction to food/milk formulas

22
Q

What are the 4 most common comorbidities of allergic rhinitis?

A

conjunctivitis, rhinosinusitis, otitis media w/effusion, asthma

23
Q

(T/F) Conjunctivitis associated with AR is commonly associated with eye discharges.

A

F

24
Q

Which is the most important part of the history in diagnosing AR?

A

environmental history

25
Q

What are the most common indoor aeroallergens according to the PGH allergy clinic?

A

house dustmite, cockroach

26
Q

(T/F) ELISA is more sensitive than the skin-prick test in determining whether there is IgE specific hypersensitivity.

A

F

27
Q

What is the gold standard radiological investigation for sino-nasal disorders?

A

coronal CT scan

28
Q

What are the components of the four-pronged approach to the management of allergic diseases?

A

allergen avoidance, pharmacotherapy, immunotherapy, patient education

29
Q

What are the pharmacologic options for mild intermittent rhinitis?

A

oral or intranasal antihistamine, intranasal decongestants, antileukotrienes

30
Q

What are the pharmacologic options for moderate-severe intermittent/mild persistent rhinitis?

A

oral or intranasal antihistamine, decongestants, antileukotrienes, chromones, intranasal corticosteroids

31
Q

What are the pharmacologic options for moderate-severe persistent rhinitis?

A

intranasal corticosteroids as first line, antihistamine or antileukotrienes, chromones

32
Q

(T/F) asthma is more common among male children

A

T

33
Q

(T/F) Chronic production of sputum in a patient would increase suspicion for asthma.

A

F

34
Q 
Which of the following is the most frequently observed respiratory abnormality in asthmatic patients?
A. expiratory wheezing
B. inspiratory wheezing
C. stridor
D. rales
A

A.

35
Q

What is the normal FEV1/FVC ratio?

A

> 0.75- 0.80 in healthy adults and >0.90 in children

36
Q

(T/F) A large bronchodilator reversilbility is supportive evidence for asthma

A

T

37
Q

What is the cut-off in PEF variation that is indicative of asthma?

A

20%

38
Q

What are the long-term goals of asthma management?

A

symptom control, risk reduction

39
Q

What are the risk factors for asthma exacerbation?

A

previous asthma intubation, uncontrolled asthma symptoms, >=1 exacerbation in the past year, low FEV1, incorrect inhaler technique, smoking, obesity, pregnancy, blood eosinophilia

40
Q

What are the risk factors for fixed airflow limitation?

A

no ICS treatment, smoking, occupational exposure, mucus hypersecretion, eosinophilia

41
Q

What are the risk factors for asthma medication side-effects?

A

frequent oral steroids, potent ICS/P450 inhibitors

42
Q

What is the prevalence rate of allergic rhinitis among asthmatic patients?

A

80%

[OS 216] Exam 2 Trans Cluster 1 (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions