leaving groups + nucleophiles Flashcards

1
Q

Good leaving groups

A

R2O
Br-
Cl-

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1
Q

Poor leaving groups

A

F-
RO-
R2N-
R3C-
strong bases are very poor leaving groups

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1
Q

Very good leaving groups

A

RSO3-
I-

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2
Q

Very good nucleophiles

A

RS-
NC-
I-
PR3
R3C-
R2N-
RCTRIPLEBONDC-
RO-

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3
Q

Good nucleophiles

A

Br-
R2S
NR3
Cl-
RCO2-
N3-

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4
Q

Poor nucleophiles

A

F-
HCO3-
R2O-
all strong acids are very poor nucleophiles

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