Learning Outcomes - Week 8 - The cell cycle Flashcards
When does Cell division occur? Explain based on the steps of mitosis and list the step in which divisions begins and completes
Occurring during meiosis and mitosis in the following steps
What are the major differences between meiosis and mitosis? Include similarities too
(See image for differences)
Similarities between mitosis and meiosis:
- Both take part in cells
- Both involve division of ceels (cell multiplication)
What is the outcome of mitosis?
2 genetically identical diploid cells
What is the outcome of meiosis?
2 genetically different haploid cells.
List and describe the main events that happen during each stage of the cell cycle
Demonstrate a familiarity with the sub-stages of mitosis. List the stages and what happens during each
Describe DNA replication (5’-3’ direction, leading, lagging strand)
What are telomeres?
What is telomerase and what does it do?
Describe cell cycle control (through checkpoints (in G1, G2 and metaphase)
Cell cycle is a highly complex and regulated
process
- Timing of events is tightly controlled
- Each individual process can be turned on and off at
the appropriate time
- Mechanisms exist to initiate each event in the
correct order and to ensure each event is only
triggered once per cell cycle
- Controls ensure events occur in a linear and
irreversible direction
Redundancy (or back-ups) ensure the cell
cycle functions properly even in the context of
malfunctioning parts
- Systems that are adaptable so that cell cycle
events can be modified in the context of
different cell types and/or environmental
conditions
- Three important checkpoints
What are the proteins that control cell cycle progression (cyclins and cyclin-
dependent kinases), irreversible direction) Explain
T/F: The cell cycle and cell cycle checkpoints are frequently deregulated
in cancer cells.
True
b
(Example of a question that is very detailed and will not be asked)
What is a major function of the CDCA3 protein during the cell cycle?
(a) Control of mitotic entry
(b) Initiates entry of S phase.
(c) Controls DNA replication.
(d) Controls chromosome segregation during mitosis.
a
