Learning outcome 1 Flashcards

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1
Q

What is the first definition for Dementia?

A

A collective name given to a group of diseases that cause progressive and irreversible damage to the brain cells

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2
Q

What is the second definition for Dementia

A

A deterioration of intellectual and cognitive functioning affecting orientation, memory and judgement

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3
Q

What is the third definition for Dementia

A

Interferes with reasoning, perception and personality, affecting normal social and occupational activities.

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4
Q

What is the fourth definition for Dementia

A

It is caused by degeneration and death of brain cells resulting in a change to the structure of the brain and a loss of function

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5
Q

Is dementia caused by aging?

A

It is age related, but not a normal part of aging. Risk of Alzheimers increases with age

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6
Q

Are there any other causes for confusion?

A

UTI, Medication, Depression, Head injury, Bereavement, Hypothermia

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7
Q

What types of dementia are there

A

Alzheimers, Vascular, Lewy body, Frontotemporal, Korsakoff, CJD

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8
Q

What’s the other name for vascular dementia

A

Multi infarct

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9
Q

What’s the other name for Frontotemporal dementia

A

Picks

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10
Q

What condition precedes Korsakoff syndrome

A

Wernickes encephalopathy

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11
Q

What does CJD stand for

A

Creutzfeldt - Jakob disease

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12
Q

What kind of proteins are related to Alzheimers

A

Amyloid, forming plaques and tau

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13
Q

What neurotransmitter is related to Alzheimers

A

Acetylcholine

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14
Q

Is Alzheimers more common in men or women

A

Women

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15
Q

Can environmental factors contribute to Alzheimers

A

Yes, i.e exposure to pollution - Particulate matter 2.5

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16
Q

What is the primary cause for Vascular Dementia

A

Mini strokes, ischemic attacks, small vessel disease

17
Q

Describe Lewy Bodies

A

Small round clumps of normal proteins that become abnormally clumped together inside neurones

18
Q

What chemicals are associated with Lewy body dementia

A

Dopamine and acetylcholine

19
Q

What protein is associated with Frontotemporal disease

A

Tau

20
Q

Which two areas of the brain does Picks affect

A

Frontal and anterior lobes

21
Q

What bodies are associated with Frontotemporal dementia

A

Pick bodies (abnormal staining is found in the brain cells)

22
Q

What chromosome is associated with Huntingtons?

A

The short arm of chromosome 4