learning goal 1 (case4) Flashcards
acidity
level of acid in a substances, ability of neurilizing acids, adding OH-
alkalinity
level of base, ability of neutrilizing bases so adding H+
strong acids
HCL, HNO3, H2SO4
weak acids
CH3COOH, H2CO3
strong basrs
NaOH, KOH
wweak base
NH3
buffer capacity
amount of strong acid or strong base that a buffer can neutrialize, without changing the buffer PH
adding strong acid to a buffer
the base in the buffer neutralize the H3O+.
buffer in blood
H2CO3 and HCO3-
wwhen is the buffer so effective
Ph and pKA are around the same value, difference of 1 is maximum
a buffer is
acid and its conugate base, base and its conjugate acid
Ka
equilibrium constant for Acids, a stands for acids,
A (aq) + B (l) ↔ BH+ (aq) + A- (aq)
Ka= [BH+] [A-]/ [A]
[acid/HA]Ka/ [conjugate base/A-]= [H3O+]
Kb
A (aq) + B (l) ↔ AH+ (aq) + B- (aq)Kb= [AH+] [B-]/ [A], also can be written as [base/HB]Kb / [conjugate acid/B-] = [OH-]
the two kind of buffers. Acidic and basic=
amphoteric
acidic buffer
mixing a large volume of a weak acid with its conjugate base
basic buffer
mixing a large volume of weak base with its conjugate acid
What are the buffers in the body
Blood and lungs, the major buffering agent is a mixture of H2CO3 (weak acid) and HCO3- (base)
Urine, the major buffering agent is a mixture of H2SO4 (acid) and PO4 3- (weak base)
- Interferior of red blood cells, this buffer system helps to maintain acidity in and around the cells. Hemoglobin makes an excellent buffer by binding to small amounts of acids in the blood, before they can alter the pH of the blood. Other proteins containing amino acid histidine are also good at buffering.
- Intracellular fluid, this is a protein buffer
extracellular fluid buffer
H2O + CO2<>H2CO3 <> HCO3- + H+
extracellular fluid buffer
Bicarbonate/ H2O + CO2<>H2CO3 <> HCO3- + H+
Inorganic phosphate/ H2PO4- <> H+ + HPO4 2-
Plasma protein (Pr)/ HPr <> H+ + Pr-
bicarbonate buffer system function
mantain blood ph (7,35<>7,45)
acidemia
below 6,8
acidemia
below 6,8
alkalimia
above 7,8
carbonic andhydrase
co2+h2o> h2co3