LE 1 Flashcards

1
Q

Due to a hypoxic event caused by hemorrhage DURING pregnancy…

A

Sheehan’s syndrome.

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2
Q

Single contour of breast and areola.

Adult hair in thickness and texture; midline distribution.

A

B5

PH4

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3
Q

TRUE OR FALSE:

Blind girls have menarche earlier.

A

TRUE

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4
Q

TRUE OR FALSE:

Peak heigh velocity is earlier in girls than in boys.

A

TRUE

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5
Q

Increase in gonadal estrogen.

A

Gonadarche

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6
Q

Irregular, prolonged, excessive menses

A

Menometrorrhagia

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7
Q

Regular, prolonged, excessive menses

A

Menorrhagia

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8
Q

How many days of no menses to consider amenorrhea?

A

90 days

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9
Q

17 years old never had menses. Breasts and pubic hair are B1PH1. Initial diagnosis?

A

Primary Amenorrhea

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10
Q

XX Karyotype

A

Mullerian agenesis/anomalies

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11
Q

XY Karyotype

A

Androgen insensitivity (Testicular feminization)

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12
Q

Formation of intrauterine adhesions secondary to uterine manipulation.

A

Ashermann’s Syndrome

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13
Q

Most common cause of primary amenorrhea

A

Gonadal dysgenesis
Turner’s syndrome
45X

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14
Q

Uterus present
Breast development absent
Elevated progesterone levels

A

17 a hydroxylase deficiency

46XX

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15
Q

Most common non-prolactin secreting tumor of the pituitary

A

Chromophobe adenoma

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16
Q

Compartment IV is disoders of ____________?

A

Hypothalamus

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17
Q

Use of OCPs inhibit ovulaion by acting both at these two sites.

A

Hypothalamus & Pituitary

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18
Q

Increase in dopamine will ___________ LH/FSH levels

A

Decrease (due to inhibition of GnRH release)

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19
Q

Diagnostic marker for patients with anorexia nervosa

A

Serum T3 levels

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20
Q

Most common female endocrine disorder

A

PCOS

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21
Q

Rotterdam Criteria

A
  1. Oligo-ovulation/Anovulation
  2. Ultrasound findings of polycystic ovaries
  3. Hyperandrogenism
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22
Q

Hypothalamic pituitary dysfunction has Estradiol levels of

A

> 40 pg/nl

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23
Q

Normal menstruation:
Interval
Amount
Duration

A

21-35 days
35 ml
4-7 days

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24
Q

An oocyte arrested at prophase

Enveloped by a single layer of spindle-shaped pregranulosa cells, surrounde by a basement membrane

A

Primordial follicle

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25
Q

The variable phase of menstruation.

A

Follicular

26
Q

Completed by day 5 of the follicular cycle

A

Secretion of dominant follicle

27
Q

It causes detachment of oocyte to the cumulus from the granulosa cells

A

Plasmin

28
Q

How many hours does an oocyte wait for fertilization?

A

48-72 hrs

29
Q

Dominant steroid in the luteal phase

A

Progesterone

30
Q

Hypothalamic GnRH neurons are concentrated mostly in the:

A

Arcuate nucleus

31
Q

Two things that control the menstrual cycle:

A
  1. Frequency of pulses

2. Amplitude of pulses

32
Q

Difference of gonadotropins with TSH

A

Beta subunit

33
Q

Act on theca cells to induce steroidogenesis

A

LH

34
Q

FSH acts on these cells

A

Granulosa

35
Q

Stimulates thecal androgen production

A

Inhibin

36
Q

Causes enlargement of labia majora and minora, uterus, increased fundal to cervical ratio
Cornification of vagina
Growth of ductal system of breasts

A

Estrogen

37
Q

Decreases tubal mobility
Thickening of cervical mucus
Stabilizes endometrium

A

Progesterone

38
Q

Layer of the endometrium that desquamates at the time of menses

A

Stratum functionale

39
Q

1st endocrinologic sign of menopause

A

Decreased levels of inhibin

40
Q

Menstrual cycle is controlled by the…

A

HPO axis

41
Q

Interval between menstruation and ovulation.

A

12-16 days

42
Q

Desquamation of the endometrium mainly occurs in the….

A

Uterine fundus

43
Q

Occurs because of estrogen-progesterone withdrawal

A

Menstrual bleeding

44
Q

2 mechanisms for hemostasis after menstruation

A

Hemostatic plug formation

Vasoconstriction

45
Q

Reported to occur in 10% of ovulatory women

A

Ovulatory DUB

46
Q

Reduced levls of PGF2 alpha

Normal levels of PGE

A

Anovolutary DUB

47
Q

Predominant cause of DUB among postmenarcheal and perimenopausal years

A

Anovulatory DUB

48
Q

FIGO classification

Anatomic causes

A

PALM

49
Q

L in PALM

A

Leiomyoma

50
Q

N in COIEN

A

Not yet classified

51
Q

C in COEIN

A

Coagulopathy

52
Q

What is PALM and COEIN

A

Polyp
Adenomyosis
Leiomyoma
Malignancy

Coagulopathy
Ovulatory dysfunction
Endometrial
Iatrogenic
Not yet classified
53
Q

Most objective diagnostic modality

A

Transvaginal Ultrasound

54
Q

To confirm presence of submucous myomas and polyps

A

Saline infusion sonography

55
Q

Evaluate endometrial cavity

A

Hysteroscopy

56
Q

Blind procedure performed under anesthesia

A

D&C

57
Q

Management for AUB

A

Stop bleeding

58
Q

Not for acute control of bleeding

A

GnRH agonists

59
Q

Androgenic steriod, rarely used

A

Danazol

60
Q

MOA is photovaporization with Nd-YAG laser

A

Endometrial ablation