Laz Resp Flashcards

1
Q

What are the aims of oxygen therapy compared to ventilation?

A

Oxygen therapy aims to raise the fraction of inspired oxuygen> raises gradient of oxygen at alveoli > raises oxygen absorption into blood

ventilation aims to recruit more alveoli into respiratory process by maintaining them open (increasing surface area for gas exchange)

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2
Q

what are the two types of NIV

A

CPAP
BIPAP

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3
Q

Explain pressures in CPAP

A

IPAP = EPAP

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4
Q

Explain how CPAP works

A

it provides continuous positive airway pressure
thereby holding the alveoli open during expiration to avoid collapse
this is especially useful when there is some lung frailty / issues making it more likely for alveoli to collapse

thereby increasing alveolar recriutment means MORE OXYGENATION

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5
Q

what conditions is CPAP useful in then

A

in T1RF (hypoxia with normocapnia)

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6
Q

what are pressures like in BiPAP and what does BiPAP stand for

A

Bilevel Positive Aiway P

IPAP > EPAP
e.g. IPAP=10, EPAP=5

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7
Q

what does BiPAP do that CPAP doesn’t

A

The difference between I and E PAP creates a gradient, so patient can breathe out some of the carbon dioxide that they are retaining

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8
Q

what conditions is BiPAP used for then

A

used for T2RF (hypoxia with hypercapnia)

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9
Q

what are three common gram positive bacteria

A

staph
strep
c diff

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10
Q

what kinds of infections do gram +ve bacteria commonly cause

A

pneumonia
skin infection
colitis
sepsis

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11
Q

what are the three main categories of antibiotics that work well for gram +ve

A

Beta lactams
Glycopeptides
Oxazolidinones

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12
Q

List beta lactams

A
  • Penicillins (amoxicillin, fluclox, tazocin)
  • cephaosporin (cefalexin, ceftriaxone, cefuroxime)
  • carbapanem (meropenem)
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13
Q

What is the most broad spec antibiotic active against almost all gram +ves

A

Meropenem

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14
Q

List glycopeptided

A

vancomycin
teicoplanin

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15
Q

list Oxazolidinones

A

linezoid

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16
Q

what is linezoid typically used against

A

MRSA

17
Q

list examples of gram neg bacteria

A

E coli
P aeroginosa
K pneumonia
Salmonella

18
Q

What infections are typically caused by gram negs

A

UTI
Pneumonia
GI infection

19
Q

what antibiotic classes work against gram negs

A

aminoglycosides
fluoroquinolones

20
Q

list some aminoglycosides

A

gentamicin
amikacin

21
Q

what is a side effect of aminoglycosides

A

renal failure - be aware of renal monitoring as NEPHROTOXIC

22
Q

list some fluoroquinolones

A

ciprofloxacin
levofloxacin

23
Q

what are two other categories of antibiotics

A

tetracyclines
nitroimidazoles

24
Q

list examples of tetracyclines and what they are good for

A

doxy, tigecycline
useful for chlamydia, mycoplasma > STI or pneumonia

25
Q

list examples of nitroimidazoles and what infections they are used for

A

metronidazole
good for anaerobes e.g. aspiration pneumonia, abscess