Lassa fever + dengue Flashcards

1
Q

what is it lassa

A

rna virus

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2
Q

epidemiology lassa

A

west africa occurs between Nigeria and Senegal

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3
Q

family lassa

A

from the arena virus

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4
Q

symptoms lassa

A

gradual as along the class of VHF , only arena virusss have a gradual onset

starts with a flu like, sore throat, fever, chills, headache

severe: facial and neck swelling and conjunctival edema pleural effusions/pneumonitis

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5
Q

tx lassa

A

ribavirin may reduce mortality by 10 x if started early (within 6 days of onset) - treat for 10 days

anti lassa fever plasma as an adjunct in very ill patients?

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6
Q

IP

A

around 10 days

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7
Q

prophylaxis of Lassa fever

A

close up pots and pan don’t let rats near them, wear goggles, high efficiency masks

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8
Q

how is the disease spread lassa

A

by rats mastomys natalensis

or human to human via bodily fluids

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9
Q

what’s important to note about Lassa fever

A

its spread is important in hospital setting

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10
Q

how is dengue spread

A

mosquito and the same mosquito than can pass on yellow. fever too Aedes Egypti + another one cba

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11
Q

family of dengue

A

flavivirus

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12
Q

epi of dengue fever

A

tropics and subtropics like the carribean and south east axis , latin America

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13
Q

IP dengue

A

3- 14 days

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14
Q

phases of dengue

A

febrile stage - flue like symptoms, mP RASH , hepatomegaly etc

critical phase- not everyone goes through this

recovery - can develop a new rash

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15
Q

prevention dengue

A

there isa vaccination but unfortunately you may not be protected but it will reduce your symptoms and length of infection

Don’t give mosquitoes places to breed. They lay their eggs in water. So get rid of standing water in things like wading pools and gutters. Change the water in birdbaths, dog bowls, and flower vases every few days.

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16
Q

treatment of dengue

A

often supportive, but try to avoid ibuprofen as you don’t want to exggertae the thrombocytopenia even more , can use parectomol for relief

17
Q

epidemiology of dengue long one

A

Dengue epidemics tend to have seasonal patterns, with transmission often peaking during and after rainy seasons. There are several factors contributing to this increase and they include high mosquito population levels, susceptibility to circulating serotypes, favourable air temperatures, precipitation and humidity, all of which affect the reproduction and feeding patterns of mosquito populations,

18
Q

sequele lassa

A

transient blindness
deafness in 5%
alopecia

19
Q

mortality rate of lassa

A

can be up to 45% however, in women who were pregnant or who delivered within 1 mo, mortality was 50%.

20
Q

who’s more at risk for dengue hemorrhagic fever/DSS

A

girls <10

21
Q

mortality of dengue

A

up to 30%

22
Q

rf for dengue list

A

age - Susceptibility to DHF/DSS drops considerably after 12 years of age.

Sex - Females are more often affected than males.

Race - Caucasians are more often affected than blacks.

Nutritional status - Malnutrition is protective.