Lasers Flashcards

1
Q

LASER

A

 Light Amplification by Stimulated Emission of Radiation

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2
Q

what are lasers

A

 Laser is a source of coherent directional (collimated ie parallel) monochromatic
(single wavelength) light

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3
Q

electrons in laser

A

 Electrons can move between different orbits at different energy levels within an
atom
 This is accompanied by absorption or emission of a photon
 Stimulated emission: a stimulating photon can cause an atom that is in an
excited state to emit another photon which will have the same phase, direction
and wavelength as the stimulating photon

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4
Q

what happens to achieve light amplification

A

the optical material needs to have more excited
atoms than lower state atoms so that emission occurs more than absorption
 This state is achieved by “inversion of population” using an excitation source
(which could be a discharge lamp, pulsed flash lamp, electric discharge,
chemical reaction, other laser or electron beam etc.)

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5
Q

what can the lasing materilal be

A

a gas, liquid or solid and light energy is “pumped” into
it by a power source.

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6
Q

lasers and cavity

A

require a cavity (optical resonator) bordered by two mirrors which
circulated the emitted light through the lasing material so that it stimulates the
emission of new photons

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7
Q

laser and mirror

A

A fraction of the photons escapes via one mirror (semi-transparent) to form the
laser beam
 Continuous production of light occurs in a laser in continuous-wave (CW)
mode

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8
Q

q-switched mode

A

a time-variable absorber can be
incorporated so that laser output is brief and very powerful. An absorber (eg.
rotating mirrors, saturable dye cells and electro-optic switches) blocks one of
the mirrors so that the lasing material is raised to high energy levels but
resonance does not occur. Population inversion is very great in this case. If the
absorber suddenly becomes transparent, a single, powerful pulse is emitted

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9
Q

convex lens in laser

A

used to focus a beam to spot with fixed diameter

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10
Q

lasers in optical fibres

A

used to transport lasers via total internal reflection and
deliver them to tissues

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11
Q

define a fundametnal mode

A

 Energy focussed on the smallest spot is known as the fundamental mode

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12
Q

wavelength range of ophthalmic lasers

A

193nm to 10800nm (including the
visible spectrum).
 The shorter the wavelength, the higher the frequency and energy

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13
Q

laser tissue interactions

A

: depend on the wavelength, pulse duration and irradiance
(power per unit area)

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14
Q

photochemical reaction

A

eg. photo-transduction in photoreceptors. Used in
photodynamic therapy in ARMD or corneal crosslinking. Very low irradiances
and long exposures

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15
Q

photo-thermal reaction

A

tissue effects depend on the temperature but range from necrosis
to coagulation and vaporization.

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16
Q

photo-thermal reaction in PRP

A

pulses of 10-200ms and transient hyperthermia.
Nd:YAG (532nm) are currently most commonly used for this.
The energy is absorbed mainly by the melanin in the RPE and choroid and by
haemoglobin (only about 5% is absorbed by the neural retina)

17
Q

photo-thermal reaction in PASCAL

A

semi-automated pattern scanning
photocoagulator that delivers square arrays of up to 5×5 spots ir rings or
arcs for macular photocoagulation. Focal or grid laser is used for macular
oedema: mechanism of effect is debated. It may stimulate RPE and
endothelial cell proliferation to strengthen the inner blood-retinal barrie

18
Q

photo-thermal reaction in Argon and Nd:YAG

A

used in laser trabeculoplasty for IOP
control (it is thought that thermal burns in the TM contract the tissue and
open spaces within the TM to increase aqueous flow. Selective Laser Trabeculoplasty uses lower energy laser than Argon and leaves the TM
intact with minimal damage to the endothelial cells or scarring. The IOPlowering effects of LT diminish with time

19
Q

krypton-red

A

Krypton red (646nm) is useful to penetrate vitreous haemorrhage for
PRP

20
Q

photo-mechanical

A

photoablation and photodisruption occur when laser
absorption results in tissue temperature exceeding the vaporization threshold
(100-305 degrees C). Expanding and collapsing vapor bubble lead to tissue
rupture and ejection of tissue fragments

21
Q

argon laser

A

wavelength: blue (488nm) and green (514)
uses: outer retina, iris (thermal, photocoagulation)
notes: goldstandard for ROP, not used for macular as much due to blue light component

22
Q

krypton

A

wavelength: yellow (568nm) and red (647nm)
uses: macula
notes: xanthophyll pigment does not absorb this wavelength as much as CP argon

23
Q

Helium-neon (He-Ne)

A

wavelength: 630bm
uses: aiming beam
notes: low power

24
Q

Diode lasers

A

wavelength: 790-950nm (infrared)
uses: CB destruction
notes: semi-conductor, extremely compact

25
Q

Neodymium-yttrium-alum-inim-garnet (Nd-YAG)

A

wavelength: 1065nm (infrared)
uses: ionising, caps, PI
notes: usually used in q-switch mode

26
Q

excimer

A

wavelength: argon fluoride 193nm (UV)
uses: corneal cutting
notes: photoablation

27
Q

carbon dioxide

A

wavelength: 10600nm (infrared)
uses: vaporising, bloodless incisions
notes: 90% absorbed within a thickness of 200microns

28
Q

complications of PRP

A

 CNVM
 Tractional RD
 ERM
 Angle-closure glaucoma: secondary to choroidal effusion
 Vitreous haemorrhage
 Foveal burns
 Retinal vascular occlusions

29
Q

scanning laser poliarimetry

A

Utilises the birefringent properties of the RNFL: birefringent because the axons are
arranged in a parallel fashion
 Polarised light passes through the nerve fibre layer and is reflected back
 This induces an alteration in its polarisation: the degree of change is known as
retardation
 This can be used for RNFL thickness measurement