LAS 1 (SEDATIVE-HYPNOTIC) - BARBITURATE

Question 1

POSITION 5

Answer 1

SUBSTITUENT REQUIRED FOR ACTIVITY

Question 2

WHAT INCREASES ONSET IN BTE?

Answer 2

INCREASE IN POSITION 5 HYDROCARBON SUBSTITUENT (UP TO 7-9)

Question 3

WHAT DECREASES ACTIVITY IN BTE?

Answer 3

ALKYLATION A POSITION 1
TRANSITION TO (S) AT POSITION 2

Question 4

WHAT ARE THE CLINICAL USE OF BTE?

Answer 4

AIDS ANXIETY BEFORE/AFTER SURGERY
CONTROLS SEIZURE EPISODE
INSOMNIA
RELIEVES STRESS (NOT FOR ANXIETY DISORDER AS IT IS ADDICTIVE)