Larynx/pharynx/vocal pathoma + partial FA 12/07 Flashcards
What part of upper resp. will be affected by alcohol and tabaco? What disease?
Larynx –> vocal cords. Laryngeal carcinoma.
What cell carcinoma is laryngeal carcinoma?
Squamous cell carcinoma arising from the epithelial lining of the vocal cord.
What part of upper resp. if affected if patient has horseness?
Larynx. Appears in Croup, vocal cord nodules, laryngeal papilloma and laryngeal carcinoma.
What disease can result in acute airway obstruction?
Acute epiglottitis.
What disease appears with inspiratory stridor?
Acute epiglottitis, croup, laryngeal carcinoma.
HPV 6 and 11 cause …………………..
Laryngeal papilloma.
Koilocytic change in biopsy is seen in ………………………
Laryngeal papilloma.
Nasopharyngeal carcinoma in LM appears as ………………… + …………………………….
Keratin positive epithelial cells + background of lymphocytes.
Angiofibroma morphology: ……………….. + ……………………..
Large blood vessels + fibrous tissue.
What sinuses are tipically affected in rhinosinusitis?
Maxillary.
Which sinus drains against gravity?
Maxillary.
What drains superior meatus?
Sphenoid, posterior ethmoid.
What drains middle meatus?
Frontal, maxillary, anterior ethmoid.
What drains inferior meatus?
Nasolacrima durct.
Maxillary sinus is drainaged in …………….
Middle meatus.
Sphenoid sinus is drainaged in …………….
Superior meatus.
Anterior ethmoid sinus is drainaged in …………….
Middle meatus.
Frontal sinus is drainaged in ……………
Middle meatus.
Posterior ethmoid sinus is drainaged in …………….
Superior meatus.
Nasolactrimal duct is drainaged in …………….
Inferior meatus.
What is the most common cause of rhinosinusitis?
98 proc. viral URI.
Viral URI in rhinosinusitis may lead to ………………
superimposed bacterial infection. M/os: Strep. pneumonia, H. influenza, M. catarrhalis.
What sinus infection can cause cavernous sinus syndrome?
Sphenoid and ethmoid sinuses may extend to cavernous sinus.
Where most commonly accurs epistaxis? What artery affected?
Anterior nostril. Kisselbach plexus.
Where occurs life threatening hemorrhage (epistaxis)? What artery is affected?
Posterior segment. Sphenopalatine artery.
Kisselbach drive his Lexus with LEGS. What is mneumonic?
Kisselbach plexus is consisted of: superior Labial artery; anterior and posterior Ethmoidal; Greater palatine artery; Sphenopalatine artery.
Rhinitis - inflamation of what?
nasal mucosa
Rhinitis most common cause?
rhinovirus/adenovirus
Rhinitis presentation?
sneezing, congestion, runny nose (common cold)
Sneezing, congestion, runny nose (common cold)?
Rhinitis
Allergic rhinitis - hypersentisivity?
type I
Allergic rhinitis characterized by?
inflammation with eosinophils
Inflammation with eosinophils?
Allergic rhinitis
Allergic rhinitis assoc with?
asthma and eczema
asthma and eczema?
Allergic rhinitis
Nasal polyp definition?
protrusion of edematous, inflammed nasal mucosa
protrusion of edematous, inflammed nasal mucosa?
Nasal polyp
Nasal polyp causes?
Secondary to repeated bouts of rhinitis
Secondary to repeated bouts of rhinitis?
Nasal polyp
Nasal polyp occurs in …… (2)
cystic fibrosis and aspirin-intolerant asthma
cystic fibrosis assoc with what?
Nasal polyp
aspirin-intolerant asthma assoc with what?
Nasal polyp
aspirin-intolerant asthma characterized by the?
- Triad of asthma
- Aspirin induced bronchospasm
- Nasal polyp
- Triad of asthma
- Aspirin induced bronchospasm
- Nasal polyp?
aspirin-intolerant asthma
Angiofibroma - origin?
Nasal mucosa
Angiofibroma classically seen in?
adolescent males
Angiofibroma clinical presentation?
profuse epistaxis
profuse epistaxis due to?
Angiofibroma
Nasopharyngeal carcinoma - origin?
nasopharyngeal epithelium
Nasopharyngeal carcinoma - what virus?
EBV
Nasopharyngeal carcinoma seen in what populations?
african children and chinese adults
Nasopharyngeal carcinoma differentiation?
Poorly differentiated squamous cell carcinoma
Poorly differentiated squamous cell carcinoma?
Nasopharyngeal carcinoma
Nasopharyngeal carcinoma what other clinical presentation?
involvement of cervical lymph nodes
involvement of cervical lymph nodes?
Nasopharyngeal carcinoma
Nasopharynx pathologies? (4)
Rhinitis, nasal polyp, angiofibroma, nasopharyngeal carcinoma
Rhinitis, nasal polyp, angiofibroma, nasopharyngeal carcinoma - what group?
Nasopharynx pathologies
Larynx pathologies? (5)
Acutes epiglotitis, laryngotracheobronchitis (croup), vocal cord nodules (singer’s nodules), laryngeal papilloma, laryngeal carcinoma
Acutes epiglotitis, laryngotracheobronchitis (croup), vocal cord nodules (singer’s nodules), laryngeal papilloma, laryngeal carcinoma - group of pathologies?
Larynx pathologies
Acutes epiglotitis - inflamation of what?
epiglottis
Acutes epiglotitis - cause?
H. INFLUENZAE TYPE B, esp. in non-immunized children
H. INFLUENZAE TYPE B - cause of what?
Acutes epiglotitis
Acutes epiglotitis clinical presentation?
high fever, sore throat, drooling with dysphagia, muffled (prislopintas) voice, inspiratory stridor
high fever, sore throat, drooling with dysphagia, muffled (prislopintas) voice, inspiratory stridor?
Acutes epiglotitis
laryngotracheobronchitis (croup) - inflammation of what?
upper airways
laryngotracheobronchitis (croup) - cause?
Parainfluenza virus
Parainfluenza virus - causes what?
laryngotracheobronchitis (croup)
laryngotracheobronchitis (croup) - presentation?
hoarse, ,,barking” cough, inspiratory stridor
hoarse, ,,barking” cough, inspiratory stridor?
laryngotracheobronchitis (croup)
Vocal cord nodules (singer’s nodules) - location?
TRUE vocal cord
Vocal cord nodules (singer’s nodules) - causes.
excessive use of vocal cords. BILATERAL
Vocal cord nodules (singer’s nodules) - histology?
Degenerative (myxoid) connective tissue
Vocal cord nodules (singer’s nodules) - presentation ant treatment?
Hoarseness;
resolve with resting of voice
Hoarseness;
resolve with resting of voice?
Vocal cord nodules (singer’s nodules)
Degenerative (myxoid) connective tissue
Vocal cord nodules (singer’s nodules)
Laryngeal papilloma - definition?
Bening tumor of the vocal cords
Bening tumor of the vocal cords?
Laryngeal papilloma
Laryngeal papilloma - causes?
HPV 6 and 11–> koilocytic changes in microscopy
Laryngeal papilloma - number in adults and childrens?
Adults - single
Children - multiple
Laryngeal papilloma - presentation?
hoarseness
HPV 6 and 11–> koilocytic changes in microscopy?
Laryngeal papilloma
Laryngeal carcinoma - origin and location?
Squamous cell carcinoma arising from epithelium lining the vocal cords
Squamous cell carcinoma arising from epithelium lining the vocal cords?
Laryngeal carcinoma
Laryngeal carcinoma - risk factors?
Alcohol and tabaco
Laryngeal carcinoma can arise from?
Laryngeal papilloma
Laryngeal papilloma may progress to?
Laryngeal carcinoma
Laryngeal carcinoma - presentation?
Hoarsenes, cough, stridor
Hoarsenes, cough, stridor?
Laryngeal carcinoma