Larynx Flashcards

1
Q

Where does the trachea begin?

A

Lower border of cricoid cartilage.

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2
Q

What may you do if a patient can not be incubated due to swelling of vocal cords?

A

Cricothyroidotomy

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3
Q

What do the superior and inferior free margins of the quadrangular membrane form?

A

Superior - aryepiglottic folds - laryngeal inlet

Inferior - vestibular ligament - false vocal cords

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4
Q

What forms the true vocal ligament?

A

Superior free border of the cricothyroid membrane thickening

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5
Q

What is the laryngeal ventricle?

What does it lead into and what is the function of this area?

A

Small recess between the vestibular and vocal folds

Leads laterally and superiorly into the saccule

Contains mucous gland - keep folds moist.

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6
Q

What are the true vocal cords lined with?

A

Stratified squamous epithelium

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7
Q

Describe the action of cricothyroid.

A

Tips thyroid cartilage forward on the cricoid cartilage increasing tension in the vocal cords Creating higher pitch noise

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8
Q

What muscles narrow the laryngeal inlet and pull down the epiglottis?

What is this assisted by?

A

Muscles running in the ary-epiglottic folds.

Elevation of the larynx due to pharyngeal muscles and suprahyoids.

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9
Q

What is the sensory innervation to the subglottis?

A

Recurrent laryngeal nerve

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10
Q

What vessel is the RLN associated with?

A

Inferior thyroid artery

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11
Q

Which RLN is more affected with cancer involving apex of the lung?

A

Right RLN

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12
Q

What causes the pinching off of the Rathke’s pouch?

A

Development of the sphenoid bone as it ossifies.

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13
Q

Where do the tongue muscles originate?

A

Occipital somites

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14
Q

What is treacher-Collins syndrome characterised by?

Inheritance pattern?

Which arches are not colonised?

A

Hypoplasia of mandible and facial bones

Autosomal dominant

1st

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15
Q

What 2 endocrine organs are not seen in Di-Georgia syndrome?

CATCH22?

Pathophysiology?

A

Thymus
Parathyroid glands

Deletion on 22nd chromosome

3 and 4th pharyngeal pouches’ development is disrupted due to abnormal neural crest development

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16
Q

What is CHARGE syndrome caused by?

Why does it cause this?

A

CHD7 - autosomal dominant mutation

CHD7 is essential for production of multipotent NC

17
Q

What is the function of CHD7?

A

Chromodomain helicase DNA-binding domain, ATP-dependant chromatin remodeller

Allows for expression of certain parts of chromosomes.