Laryngology, Salivary glands, Endocrine Flashcards
Only vocal abductor and nerve
Posterior Cricoarytenoid, inervated by reccurent laryngeal nerve)
Plays biggest role in changing pitch of voice
Cricothyroid, (vocal adductor) innervated by superior laryngeal nerve
Where do most malignancies occur in the vocal fold layers?
Squamous epithelium
How mich can 1mm of edema in the air reduce the airway?
60%
Forced air across a constricted zone causes negative pressure and causes the vocal cords to close again
Bernoulli’s effect
Production of speech
Phonation
Oral/nasal speech balance
Resonation
Use of lips, teeth, tongue to produce speech sounds
Articulation
Source of speech energy
Respiration
Syllable stress, emphasis, inflection
Prosody
Most common test to evaluate speech
Videostroboscopy
Why do some pt’s “moan” or “pursed lips” breath?
Auto-PEPing
Where is the source of snoring?
Nasopharynx
Where is the source of gurgling sounds?
Oropharynx
Source of inspiratory stidor
Supraglottic
Source of inspiratory or biphasic stridor, hoarseness
Glottic
Source of barking cough
Subglottic
Expiratory stridor
Tracheobrachial
Indications for endoscopy
SPECS-R: severity of obstruction, progression of SOB, eating difficulties, cyanosis, sleep apnea, radiologic findings
Indications for tracheotomies
Bypass upper airway obstruction, prolonged intubation, pulmonary toilet, protect from aspiration, eliminate dead space with CNS depression
Trach Care
New trach = 3-5 days before making trach changes, change INNER cannula every shift/every day, HUMIDITY, minimal amount of cuff pressure to decrease scarring, infections, erosions
Most common congential laryngeal abnormality
Laryngomalacia
Most common cause of stridoe in neonate and chronic peds
laryngomalacia
S&S of laryngomalacia
Intermittent inspiratory stridor, worses with crying or feeding, has a floppy epiglottis that collapses inwards (Monitor)
Trachea collapsing from immature tracheal cartilage
Tracheomalacia
Most common vascular anomaly to cause stridor
Double aortic arch
Most common vascular anomaly to compress the digestive tract
Retroeosophageal right subclavian artery
High pitched stridor, mental retardation, microcephaly, narrowed endolarynx and interarytenoid cleft
Cri Du Chat, deletion of short arm of chromosome 5
Dysphagia, drooling, dyspnea in >1y/o
Epiglottitis, is true emergency, cuased by H. Flu
Dx epiglottitis
Thumb sign on lateral XR
Barky cough, inspiratory or biphasic stidor, NO drooling or dysphagia
Croup, caused by parainfluenza 1 virus
Dx of croup
Steeple sign with narrowed subglottis
Second most common cause of hoarseness in children
Recurrent respiratory papillomatosis, HPV 6 and 11
Most common head and neck neoplasm in children
Hemangioma
Tx for hemangioma
usually goes away, can give beta blockers
Sacoidosis: effect on larynx
Most commonly epiglottis
Wegeners granulomatosis: effect on larynx
Most commonly subglottis
Amyloidosis: effect on larynx
Anterior subglottic mass
RA arthritis: effect on larynx
Criocoarytenoid joint affected, causes hoarse voice
If bilateral contact ulcers in the middle and anterior third of vocal cords
Vocal cord abuse and trauma
Unilateral “bump” on vocal cord
Vocal cord polyp
Most common causes of vocal cord paralysis
Neoplastic causes
Unilateral vocal cord paralysis
Breathy, hoarse voice
Bilateral vocal cord paralysis
Stridor, dyspnea
ADDuctor spasmodic dysphonia
More common, sudden stop of voice
ABDuctor spasmodic dysphonia
Pt sounds breathy, botox posterior cricoarytenoid muscle
Results from histamine-mediated urticarial reactions
Aquired laryngeal angioedema
C1 esterase inhibitor deficiency
Congenital laryngeal angioedema
Polypod degeneration of superficial lamina propria
Reinkes space edema, in smokers!
Mainly serous gland
Parotid gland, stensons duct and facial nerve
Mixed serous and mucinous gland
Submandibular gland, whartons duct, facial/lingial artery, hypoglossal nerve
Mainly mucuous gland
Sublingual gland, ducts of rivinus
Tx of ptyalism and sialorrhea
Anticholinergics
What risk does xerostomia pose?
dental carries
Most common cause of acute sialadentis
Staph aureus
Acute salivary gland infection
Acute sialadentis
Stone in salivary gland duct
Acute sialoLITHiasis
Bilateral painful parotic swelling
Mumps, paramyxovirus
Firm enlargement of submandibular gland, cirrhotic changes with destruction of acinar cells
Kuttner Tumor
Dry eyes, xerostomia, partoic swelling
Sjogren Syndrome, associated with non-hodgkins lymphoma
Cyst that extends into cervical tissues and may look like a neck mass
Plunging Ranula
If a tumor is found in a small gland…
The more likely it is malignant
Most common salivary gland malignancy in children
Mucoepidermoid tumor
Most common tumor of each gland
Pleomorphic ademoa
Second most common salivary gland tumor
Warthin Tumor
Signs of salivary gland malignancy
Solitary nodule, facial nerve involvement, pain, trismus, cervical lymphadenopathy
Most common submandibular and minor salivary gland malignancy
Adenoid cystic carcinoma
Injury to auriculotemporal nerve results in aberrant innervation of cutaneous sweat glands, results in sweating while eating
Frey Syndrome
Stored in the thyroid
T3 and T4
What does TSH do?
Increases iodide uptake
Excess Iodine inhibits thyroid hormone
Wolff-Chaikoff effect
Effects of thyroid hormone
Elevates metabolic rate, releases steriod hormones, stimulates erythopoiesis, increases sympathetic activity
Free T4 is specific for…
hypo/hyperthyroidism
TSH is most sensitive test for…
primary hypo/hyperthyroidism
FNA indication
> 5mm…do if high risk or suspicious nodule
Bethesda grading system for thyroid pathology
1: need better specimen, 2:benign, 3:atypia or redo FNA, 4: follicular neoplams, so surgical lobectomy, 5:suspicious for cancer so thyroidectomy, 6:malignant so thyroidectomy
Most common FNA cytology result
Papillary cells: papillary carcinoma, but not necessarily bad prognosis, see Psammoma bodies
2nd most common FNA cytology result
Follicular cells: Common, not necessarily a bad prognosis, most common in elderly females
Aggressive FNA cytology result
Bizarre cells, suggests anaplastic carcinoma, in elderly, grows and erodes thru trachea
Decreased uptake of thyroid radionucleotide studies
Graves disease and hyperthyroidism
High risk thyroid neoplasia pts
AMES, Age (>41males, >51 females), metastatis, extent, size (>5cm)
Most common thyroid cancer
Papillary carcinoma, most common in young females, increased risk with radiation exposure and Gardner syndrome
Genes associated with Medullary Thyroid Carcinoma
MEN IIA/B mutation, RET-3 oncogene association
S&S of medullary thyroid carcinoma
elevated calcitonin and CEA
Thyroid Storm
Acute extreme state of thyrotoxicosis, sudden fever, profuse sweating, tachycardia, nausea, abd pain, tremors, restless, psychosis, coma, stupor,NEED IMMEDIATE IODINE
Cause of goiters
Iodine deficiency, iodine excess, lithium, thyroid hormone resistance
Thyroid stimulating immunoglobins stimulate hyperplasia from TSH, leading to unregulated overproduction of thyroid hormones with no negative feedback to turn off
Graves disease
Tx of Graves disease
I131, propranolol, subtotal thryoidectomy
Most common painful thyroiditis, presents usually with malaise or flu-like illness prior to pain
De Quervain, aka subactue granulomatous thyroiditis
Most common cause of hypothyroidism, chronic autoimmune
Hashimoto thyroiditis