Large Intestine Flashcards

1
Q

What are the 8 different components of the large intestine / colon?

A
Caecum
Appendix
Ascending colon
Transverse colon
Descending colon
Sigmoid colon
Rectum
Anus
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2
Q

What are the 4 functions of the large intestine

A
  1. digestion
    - minimal
    - enteric bacteria ferment some indigestible carbohydrates and synthesize vitamin B and K
  2. absorption
    - most remaining water
    - electrolytes
    - vitamins produced by bacteria
  3. Propulusion
    - haustral contractions and mass movements propel faeces to rectum
  4. Defecation
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3
Q

What are the 2 types of contractions in the LI?

A

Haustral contractions:

  • every 30 minutes
  • short lived slow contractions
  • mostly in ascending and transverse colon
  • initiated by ENS when individual haustra fill with food

Mass movements:

  • 3 to 4 times daily
  • powerful prolonged contractile waves
  • gastrocolic reflex: presence of food in stomach produces reflex mass movement
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4
Q

What is the gastrocolic reflex?

A
  • presence of food in stomach produces reflex mass movement to propel food in large intestine towards rectum
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5
Q

What is the defecation reflex?

A
  • mass movement of faeces into rectum stimulates visceral afferent neurons (distension)
  • visceral afferents initiates PNS spinal reflex at S2-4
  • PNS initiates contraction of rectum, and relaxation of internal anal sphincter
  • message also reaches brain to allow conscious decision on relaxation of external anal sphincter
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6
Q

Describe the caecum including the location, ileocecal junction, nerve supply, and vascular supply

A

Anatomy:

  • first part of LI
  • between ileum of SI and ascending colon
  • 7.5 cm length and breadth

Location:

  • right inguinal region
  • corresponds to right iliac fossa

Ileocecal junction:

  • ileocecal vavle controls passage of chyme through ileocecal orifice
  • formed by superior and inferior ileocecal folds

Vascular:

a. ileocolic artery (terminal branch of SMA)
b. ileocolic vein (drains to SMV)

Neuro:

  • PNS: CNX Vagus
  • SNS: abdominopelvic planchnic (lower Tx segments)
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7
Q

Describe the appendix including anatomy, function, vascular and innervation

A

Anatomy:

  • arises from posteromedial aspect of caecum
  • inferior to ileocaecal junction
  • 6-10cm length
  • intraperitoneal
  • small twisted lumen (susceptible to blockage)

Function:

a. immunity: contains masses of lymphoid tissue, produces and stores lymphocytes
b. reservoir for beneficial gut bacteria

Neuro:
- visceral afferents (enter at T10)

Vascular:

a. appendicular a (branch of ileocolic from SMA)
b. ileocolic v (to SMV)

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8
Q

Describe the anatomy of the ascending, transverse and descending colon

A

Ascending:

  • between caecum and right colic / hepatic flexure
  • secondarily retroperitoneal (covered by peritoneum anteriorly and laterally)

Transverse:

  • 45cm long
  • crosses abdo wall at level of umbilicus
  • largest and most mobile section of LI
  • between right colic / hepatic flexure and left colic / splenic flexure
  • two ligaments (phreniocolic to diaphragm and transverse mesocolon)

Descending:

  • between left colic / splenic flexure and sigmoid colon
  • retroperitoneal (covered anteriorly and laterally)
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9
Q

Describe the sigmoid colon

A
  • S shaped loop
  • inferior continuation of descending colon
  • 40cm long
  • extends from iliac fossa to rectum at S3
  • intraperitoneal

Rectosigmoid junction: signified by termination of teniae coli

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10
Q

What is the rectosigmoid junction?

A

The junction between the sigmoid colon and the rectum at approx S3

  • signified by the termination of teniae coli
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11
Q

What are the 4 histological features of the large intestine?

A

Teniae coli:

  • 3 separate thickened bands of muscle in the longitudinal mm layer of muscularis
  • extend from caecum to beginning of rectum
  • muscular tone puckers colonic wall into haustra

Haustra:
- pocket like sacs in walls of LI

Crypts:

  • in mucosal layer of LI
  • contain goblet cells that produce mucous to protect LI wall and ease faecal passage

Omental / epiploic appendices:
- small fatty projections of omentum hanging from surface of colon

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12
Q

What is the arterial supply of the LI?

A

Ascending colon and hepatic flexure:

  • branches from SMA
  • ileocolic and Rt colic a (from SMA)

Transverse colon:

  • middle colic a (SMA)
  • Rt colic a (SMA)
  • Lt colic a (IMA)

Descending colon:
- Lt colic
- superior sigmoid
(both from IMA)

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13
Q

Which components of teh LI are supplied by branches of the SMA, and which from the IMA?

A

SMA:

  • ascending colon
  • hepatic flexure

IMA:

  • descending colon
  • sigmoid colon

Both:
- transverse colon

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14
Q

What are the 4 branches of the SMA that supply the LI?

A
  1. Multiple intestinal branches of SMA (ascending colon)
  2. Ileocolic (ileocaecal junction, caecum)
  3. Right colic (ascending, hepatic flexure, part of transverse)
  4. Middle colic (transverse)
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15
Q

What are the 2 branches of the IMA that supply the LI?

A
  1. Left colic (transverse and descending)

2. Superior sigmoid aa (sigmoid colon)

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16
Q

What is the venous drainage of the LI?

A

Draining into SMV:

  • ascending colon and hepatic flexure (branches of SMV, ileocolic and Rt colic)
  • transverse (SMV)

Draining into IMV:
- descending and sigmoid

17
Q

What is the innervation of the LI?

A

Ascending colon, hepatic flexure and transverse colon:

  • PNS: CNX Vagus
  • SNS: T10-12

Descending and sigmoid:

  • PNS: pelvic splanchnic (S2-4)
  • SNS: Lx part of sympathetic trunk and superior hypogastric plexus
18
Q

What is the anorectal flexure?

A

the sharp postero-inferior angle at the terminal rectum, between the rectum and the anus (at tip of coccyx)

19
Q

What are the peritoneal reflections of the rectum in males and females?

A

Females:

  • rectouterine pouch (pouch of Douglas)
  • peritoneum reflecting from rectum to posterior vagina and uterus

Males:

  • retrovesicle pouch
  • peritoneum reflecting from rectum to posterior bladder
20
Q

Describe the anatomy of the rectum

A
  • between sigmoid colon (S3) and anus (tip of coccyx)
  • rectal ampulla = dilated distal part of rectum directly above pelvic floor, relaxes to accomodate faecal mass
  • puborectalis m forms a sling around inferior rectum and has a role in maintaining continence
21
Q

Describe the vascular and neuro supply of the rectum

A

Arterial:
- branches of IMA (superior rectal, middle rectal, internal rectal)

Venous:

  • superior rectal v (into portal system)
  • middle and inferior rectal v (into systemic)

Neuro:

  • intrinsic: ENS
  • PNS: pelvic splanchnic (S2-4)
  • SNS: Lx part of sympathetic trunk and superior hypogastric plexus
22
Q

Describe the anatomy of the anal canal, including location, histology and features

A

Location:

  • terminal aspect of LI
  • between pelvic diaphragm and anus
  • begins at tip of coccyx and descends 2-3cm

HIstology:

  • rectal: simple columnar
  • anal: stratified squamous

Features:

  • anal columns: longitudinal folds of mucosa
  • anal sinuses: recesses bw columns that exude mucous when compressed by faeces
  • anal sphincters: internal (involuntary control) and external (voluntary control)
  • pectinate line: junction between superior and inferior anal canal, different neurovascular supply
23
Q

Describe the innervation and vascular supply of the anal canal

A

Arterial:

  • superior to pectinate line: superior rectal (from IMA)
  • inferior to pectinate line: inferior rectal (from internal iliac)

Venous:

  • superior to pectinate ine: internal rectal plexus (to superior rectal, IMV and portal system)
  • inferior to pectinate line: internal rectal plexus (to inferior rectal and caval system)

Neuro:

  • superior to pectinate line: inferior hypogastric plexus, PNS S2-4, visceral afferents
  • inferior to pectinate line: somatic motor and sensory from pudendal (S2-4), sensitive to pain, touch and temperature