Large Bowel Obstruction Flashcards

1
Q

MC Cause of Large Bowel Obstruction

A
  • Colorectal carcinoma is the most common etiology
  • Diverticular disease is the second most common > Chronic inflammation in the sigmoid can cause a stricture

complicated diverticulitis with significant inflammation > inflammatory stricture, phlegmon, or abscess.

  • The third most common cause of large bowel obstruction is volvulus,
    involves the mesentery > High risk of strangulation and ischemia
  • Functional causes of large bowel obstruction are less common > colonic pseudo-obstruction (Ogilvie’s syndrome), narcotic-induced adynamic ileus, and adynamic ileus due to systemic illness such as toxic megacolon from Clostridium difficile infection.
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2
Q

How many cm of Cecum is concerning

A

Cecal distension of 9 to 12 cm on plain abdominal film is concerning for impending perforation.

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3
Q

MC Procedures associated with Colonic Pseudo obstruction

A

Recent orthopedic or gynecologic procedures

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4
Q

What causes air-fluid levels of the small bowel with distension.

A
  • Incompetent ileocecal valve > reflux of contents back into the small intestine may reflect as air-fluid levels of the small bowel with distension.
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5
Q

the classic findings of Volvolus on plain films

A
  • Sigmoid volvulus > “bent inner tube” sign or
    “omega loop.”
  • Cecal volvulus > “coffee bean”
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6
Q

Other classic findings of volvulus and obstructing cancer with Contrast Enema

A

“bird’s beak” deformity at the site of a volvulus

“apple core lesion” at the site of an obstructing cancer.

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7
Q

Contrast Enema Result in Pseudo obstruction and fecal impaction

A
  • Colonic pseudo-obstruction > contrast will freely flow without evidence of transition point.
  • fecal impaction > contrast may be therapeutic.
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8
Q

Who requires emergent intervention.

A
  • Patients who present with impending perforation on imaging
  • pneumoperitoneum (evidence of existing perforation),
  • peritonitis
  • clinical signs of sepsis
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9
Q

The Goal of Surgery

A

Decompress the Bowel

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10
Q

Stoma or No stoma ?

A
  • under emergent setting where the patient is unstable or with gross intraabdominal contamination

> primary anastomosis is contraindicated
Segmental resection with an end stoma is the safest choice.

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11
Q

Rt Side vs Lt Side Lesions

A

Rt Side, proximal to the splenic flexure
> right hemicolectomy with end ileostomy

Lt Side lesions >
Hartmann procedure should be performed.

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12
Q

When is subtotal colectomy is indicated

A
  • perforation
  • large serosal injuries
  • or synchronous lesions are found at the time of exploration.
  • When performing a subtotal colectomy in the emergent setting, creation of an end ileostomy is often necessary.
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13
Q

when to Consider Diverting loop colostomy ?

A
  • unresectable malignancy
  • diffuse carcinomatosis
  • severe inflammation
  • patients who are extremely unstable

> a diverting loop colostomy proximal to the obstruction is indicated

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14
Q

Loop Vs End Colostomy

A
  • A loop colostomy is preferred over an end colostomy as the blind end that is left in the abdomen may perforate.
  • A colostomy relieves patients of their symptoms and limits subsequent concerns for an anastomotic leak.
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15
Q

colostomies associated Morbidity

A
  • high rates of parastomal hernia (50%)
  • decreased quality of life
  • and low rates of stoma closure.
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16
Q

Non emergent Setting for Rt side Lesion

A

In the absence of generalized peritonitis, perforation, or sepsis

  • Rt side obstruction and the point of obstruction is proximal to the splenic flexure >
    right hemicolectomy with primary anastomosis

low anastomotic leak rates (< 5%)

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17
Q

Alternative ?

A
  • Right hemicolectomy with primary anastomosis and proximal diverting loop ileostomy.
  • Considered in patients with high Concern for leak and may delay chemo later
    > Small bowel dilation
    > immunosuppressed
    > on steroids
    > or malnourished from chronic obstruction

Additionally, reversal of a loop ileostomy is a less morbid surgery than reversal of an end ileostomy.

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18
Q

Obstructing lesion arising in the descending sigmoid colon, rectum, or anus

A
  • Traditionally, primary anastomosis at the initial procedure was avoided because of the higher rates of anastomotic leak (20%).
  • Currently, segmental resection with primary anastomosis is a good option for carefully selected patients if the proximal colon is not dilated significantly.
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19
Q

High Risk patient with Left side Obstruction

A
  • Segmental colectomy, anastomosis, and a diverting loop ileostomy.
  • This still allows for diversion of the fecal stream
    > in the event of an anastomotic leak
    intraabdominal sepsis is contained and can usually be managed nonoperatively with percutaneous drainage and antibiotics
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20
Q

Loop ileostomy vs Hartmann’s

A
  • Loop ileostomy reversal is a less invasive operation and patients will more likely undergo this procedure to have their intestinal continuity restored as compared to reversing a Hartmann’s procedure.
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21
Q

Colonic Lavage

A
  • Colonic lavage may permit a single-stage surgery in the setting of a left-sided large bowel obstruction.
  • Following the resection
  • colon fully mobilized at both hepatic and splenic flexures
  • Allow descending colon to extend beyond the abdominal cavity
  • Appendectomy is performed, and a catheter is passed into the cecum and secured with a purse-string suture.
  • Catheter is attached to a large bag of warmed saline
  • If the cecum is thinned, insert the catheter into the terminal ileum
    -The staple line at the distal segment of colon is opened and a generous length of sterile corrugated tubing is placed into the lumen of the descending colon.
  • 3-6 Liters of warmed saline is then flushed through the colon.
  • This is continued until the effluent clears
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22
Q

With Colon Lavage, Before Anastomosis Do What ?

A

Before the anastomosis,
- the colon is inspected for injuries that may have occurred during the lavage.
> anastomosis is then performed
either end-to-end or side-to-side if there is a large bowel size discrepancy.

23
Q

Alternative Method ?

A

A modified version of this method uses a Y-shaped connector
> One limb allows for retrograde infusion of saline through the descending colon and the other is attached to drainage tubing.

> obviates the need for the appendectomy or cecostomy.

24
Q

Indications for Stent and Why ?

A
  • Palliation of an inoperable obstructing lesion (e.g., stage IV colorectal cancer)
  • Temporizing “bridge” to definitive therapy in a patient with a curable or potentially curable lesion.

To Allow colonic decompression
medical optimization
endoscopic evaluation for synchronous lesions
and increases the likelihood of a single-stage operation.

25
Q

Contraindications to stent placement

A
  • Any indications for emergent surgery
  • an abscess/ infection closely associated with the lesion
  • Short and tethered colon
  • Lesion less than 5 cm from the anal verge.
26
Q

MC Feared Complication of Stent and how to decrease it ?

A
  • Perforation

> To mitigate the procedural risk of perforation, insufflation with carbon dioxide is preferred over room air because of the dramatically faster clearance time.

27
Q

The most common stents used

A
  • uncovered, self-expanding metal stents (SEM).
  • Through-the-scope (TTS) and over-the-wire, also referred to as non-TTS,
28
Q

Pre Stent Should do What ?

A
  • No need Abx
    -Gentle tap water enemas should be used to evacuate stool
  • Oral bowel preparation > only if the obstruction is partial
29
Q

How to put stent ( overlap ) ?

A

Most TTS systems encourage a proximal and distal stent overlap of 2 cm

30
Q

To reduce development of rapid restenosis

A

the intraluminal diameter at the midportion of the stent should be at least 24 mm.

31
Q

If imaging does not demonstrate flaring at one or both ends of the stent

A
  • Additional stenting is likely necessary and typically done in an end-to-end fashion.
32
Q

Patients should expect gradual improvement of symptoms over

A
  • 3 to 5 days as the stents reach maximal expansion and the colon decompresses.
33
Q

For descending colon and beyond, patients are advised to consume

A
  • low-residue, low-fiber diet along with daily laxatives (e.g., polyethylene glycol) to promote soft stools that are unlikely to become impacted at the stent.
34
Q

When should definitive therapy happen after Stent

A
  • Should be done within 7 to 14 days following placement of the stent.
  • Patients who receive stenting for palliation and the anticipated duration greater than 2 weeks have a significantly increased risk of stent complications, primarily perforation.
35
Q

Success Rate , Complications, Factors for failure

A
  • Successful stent placement for acute large bowel obstruction between 70% and 90%.
  • 25% Risk of Complications
    > Most common complications stent migration, reobstruction, and perforation.

perforation > 4% to 5% of patients.

Intrinsic factors that may increase the risk of stent-related perforation include
> longer segment of obstruction (median length of 64 mm), benign etiology, and extraluminal origin.

36
Q

The two primary goals for management of sigmoid volvulus

A
  • Relieve the obstruction
  • prevent recurrence.

The gold standard in the management of uncomplicated sigmoid volvulus is endoscopic detorsion,
gross inspection
and placement of a drainage catheter
(successful in up to 70%– 90% of patients).

Converts an emergency situation into an elective one

Failure of endoscopic reduction and/ or presence of bowel ischemia is an indication for emergent resection

37
Q

Rate of recurrence

A

50% to 80% range.

38
Q

Types of cecal Volvulus

A
  1. Axial cecal volvulus: A twist of the intestines in which the affected cecum remains in the right lower quadrant
  2. Loop cecal volvulus: The cecum and terminal ileum are twisted in the axial plane and the affected cecum typically lies in the left upper quadrant.
  3. Cecal bascule: A redundant cecum folds in the sagittal plane onto itself and the proximal ascending colon leaving the affected cecum within the right upper quadrant.
39
Q

Which one is common

A
  • Types 1 and 2 are the most common, accounting for roughly 80% of cecal volvuli.

Unlike types 1 and 2, type 3 does not exhibit torsion.

40
Q

Endoscopy role ?

A

Endoscopic management is not recommended for cecal volvulus or bascule because of a low rate of successful detorsion, and colonic ischemia can be missed in up to 25% of patients.

41
Q

Management

A
  • Nonviable cecum > resection and creation of end ileostomy, with consideration for mucous fistula.
  • If the cecum is viable or with patchy ischemia, there is less consensus on the appropriate management.
  • Nonresectional options include detorsion with cecopexy and cecostomy.
42
Q

Distillation of the current data favors

A

ileocecectomy with primary anastomosis for patients with acute cecal volvulus, even when bowel appears viable.

43
Q

Patient with Ogilvie can pass stool ?

A

A significant portion of these patients will continue to pass loose stool.

44
Q

The gold standard imaging modality

A

CT
> Diffuse colonic distension, possible transition point near splenic flexure, and, importantly, no evidence of a mechanical obstruction.

45
Q

Non Op Tx

A
  • Aggressive fluid resuscitation
  • repletion of serum electrolytes
  • cessation of possible offending medications
    (e.g., opioids, anticholinergics)
  • bowel rest.
  • Nasogastric and rectal tubes for decompression
  • Continued for up to 72 hours.

Monitor the patient > serial imaging and physical examination.

46
Q

Failure to improve over this period

A
  • Neostigmine. ( antiacetylcholinesterase mechanism )
    > increases the availability of acetylcholine
    > improved contractility and generalized motility.
47
Q

Before Given Neostigmine

A
  • Before administration
    > Transferred to a unit with continuous cardiopulmonary monitoring
    > Keep atropine, glycopyrrolate, or both Ready
48
Q

Neostigmine is contraindicated in

A
  • Suspicion for ischemia or perforation
  • severe acute bronchospasm
  • poorly controlled cardiac dysrhythmia
  • or pregnancy.
49
Q

How its given

A
  • Continuous monitoring
  • the first dose > 2 to 5 mg is given intravenously over 1 to 5 minutes.
  • Success is achieved with passage of flatus, stool, or decreased abdominal distension.
  • Patient observed > next 80 minutes.
  • Atropine and glycopyrrolate should be readily available if there is development of bradycardia or bronchospasm, respectively.

successful in more than 90% of cases.

50
Q

or patients who are partial responders or nonresponders after one dose

A

Second Dose can be administered with high rates of success.

51
Q

who fail to respond to neostigmine, the next step in management is

A
  • Endoscopic decompression
  • clinical success in 95% > single intervention
  • 18% needed at least one additional colonoscopy

for patients who did not receive a decompression tube at the time of the procedure, clinical success was only achieved in 25%.

52
Q

technical considerations

A
  • insufflation minimized with carbon dioxide
  • The scope advanced into the right colon.
  • A decompression tube is strongly recommended should originate from the right colon
  • Evidence support the use of polyethylene glycol solution after endoscopy and neostigmine to lower recurrence rate.
  • Remove as much gas as possible during withdrawal
53
Q

If endoscopic decompression is not possible or unsuccessful

A
  • Percutaneous cecostomy

Then Last :
- Operative management > minilaparotomy assess the viability of the colon
If no evidence of perforation or ischemia, a tube cecostomy or surgical cecostomy may be sufficient.

If ischemia > affected region should be resected, including subtotal colectomy if indicated.
Primary anastomosis is not recommended but rather the creation of end colostomy with or without mucous fistula.