Large Bowel🥳 Flashcards

1
Q

APPENDICITIS pathophysiology?

A
  • normally direct luminal obstruction (by what?). also by lymphoid hyperplasia, impacted stool or rarely appendiceal/caecal tumour
  • now commensal bacteria multiply leading to acute inflammation
  • also reduced venous drainage
  • both lead to inc pressure in appendix -> ischaemia
  • untreated? necrosis … perforation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

APPENDICITIS risk factors?

A
  • FHx : ?% risk?
  • ethnicity : more common in? greater risk of perf in?
  • environmental: during what season is common?
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

APPENDICITIS clinical features?

A
  • abdo pain. peri umbilical (dull & poorly localised - why?) —> RIF (sharp & well localised - why?)
  • vomiting (before or after pain?)
  • anorexia
  • nausea
  • diarrhoea/constipation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

APPENDICITIS on examination?

A
  • rebound tenderness & percussion pain & guarding over McBurney’s point (where is this?)
  • severe? sepsis signs eg ?
  • *appendiceal abscess may also present w RIF mass
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

APPENDICITIS specific signs on examination?

A
  • rovsings sign - RIF pain on palpation of ?

- psoas sign - RIF pain with extension of right ? (suggests retrocaecal appendix)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

APPENDICITIS differential diagnoses?

A
  • gynae: ovarian cyst rupture, ectopic, PID
  • renal: ureteric stones, UTI, pyelonephritis
  • GI: IBD, meckel’s diverticulum, diverticula disease
  • urological: testicular torsion, epididymo-orchitis
  • **specifically in children? gastroenteritis, constipation, intussusception or UTI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

APPENDICITIS lab tests?

A
  • urinalysis- why? when can leukocytes be present in the urine still?
  • preg test
  • bloods - fbc, crp
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

APPENDICITIS imaging?

A

clinical diagnosis is normally sufficient.
if clinical features inconclusive:
- USS - first line (especially transvaginal if other gynae pathology differentials). why is it good in kids?
- CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

APPENDICITIS management?

A
  • definitive treatment : laparoscopic appendicectomy

- maybe conservative antibiotic therapy in uncomplicated appendicitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

APPENDICITIS complications?

A
  • perf -> peritonitis
  • surgical site infection
  • appendix mass - what is this?
  • pelvic abscess - presents as palpable RIF mass, confirmed w CT, management?
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

DIVERTICULAR DISEASE information

A
- diverticulum = outpouching through bowel wall. common in sigmoid 
4 manifestations of this condition:
- diverticulosis - ?
- diverticular disease - ?
- diverticulitis- ?
- diverticular bleed - ?
- M>F, developed countries
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DIVERTICULAR DISEASE pathophysiology

A

aging bowel has become weakened over time -> stool inc luminal pressure -> results in outpouching of the mucosa through the weaker areas of the bowel wall

bacteria can overgrown in the outpouchings leading to inflammation. they can perf leading to diffuse peritonitis sepsis

chronic? fistula can form. what ones are most common?x2

diverticulitis is either simple (?) or complicated (?)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DIVERTICULAR DISEASE risk factors?

A

inc age, low dietary fibre, obesity, smoking, fhx, nsaid use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DIVERTICULAR DISEASE diverticulosis clinical features?

A

asymptomatic and found incidentally on ct or routine colonoscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

DIVERTICULAR DISEASE clinical features?

A

intermittent lower abdo pain - colicky in nature & relieved by defecation
other sx: altered bowel habit, associated nausea, flatulence. no systemic features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

DIVERTICULAR DISEASE acute diverticulitis clinical features ?

A
  • acute abdo pain, sharp, localised in the left iliac fossa, worsened w movement
  • perf? signs of localised peritonism or generalised peritonitis. V UNWELL
    • what meds can mask sx of diverticulitis?
17
Q

DIVERTICULAR DISEASE differentials?

A

IBS, bowel CA, mesenteric ischaemia, gynae causes, renal stones

18
Q

DIVERTICULAR DISEASE investigations?

A
  • bloods: what ones?
  • urine dip - why?
  • CT AP - what findings?x5
  • uncomplicated diverticular disease ? flex sig
19
Q

DIVERTICULAR DISEASE management ?

A
  • uncomplicated dd? analgesia, oral fluid intake encouragement. out pt colonoscopy to exclude CA
  • diverticular bleeds? manage conservatively as mostly self limiting. significant bleeding? resus w appropriate blood products + stablisation
    fail to respond? embolisation or surgical resection
  • acute diverticulitis? conservative mgmt - abx, iv fluids, analgesia. sx tend to improve in 2-3 days. clinical deterioration ? repeat imaging
20
Q

DIVERTICULAR DISEASE surgical management?

A
  • in pts w perf w faecal peritonitis or overwhelming sepsis
  • hartmanns procedure (what is this?)
    • an anastomoses w reversal or colostomy may be possible at a later date
21
Q

DIVERTICULAR DISEASE complications?

A
  • recurrence
  • diverticular stricture - following repeated episodes of inflammation. bowel becomes scarred and fibrotic resulting in a benign stricture. can cause large bowel obstruction so sigmoid colectomy needed
  • fistula - due to repeated inflammation. most common types?? how do they present??
22
Q

CROHNS clinical features?

A

episodic abdo pain (colicky), diarrhoea (may contain blood or mucus). systemic sx: malaise, anorexia, low grade fever, malabsorption & malnourishment. oral aphthous ulcer & perianal disease
extra intestinal features: msk (?), skin (?), eyes (?), HPB (?), renal (?)

23
Q

CROHNS investigations?

A
  • bloods -?
  • faecal calprotectin
  • gold standard - colonoscopy
24
Q

CROHNS management ?

A
  • medical : gastroenterologist. induce remission:1st corticosteroid then azatioprine etc. maintain remission:azathiprine, smoking cessation. colonoscopies offered if has disease for >10 yrs and >1 segment of bowel affected due to inc CA risk. IBD nurse specialist
  • surgical: if failed medical mgmt or severe comps (eg strictures or perks). ops inc: ileocaecal resection, small bowel/large bowel resection, peri anal disease surgery, stricturoplasty. ** pre op optimisation important !!
25
Q

CROHNS comps?

A
  • gi: fistula, stricture, recurrent perianal fistula, gi CA
  • extra intestinal : malabsorption,osteoporosis, inc risk gallstones, inc risk renal stones

explain all above!!!

26
Q

UC clincial features?

A

insidious in onset - bloody diarrhoea, proctitis, pr bleed, mucus discharge, inc fre & urgency defecation, tenesmus
more widespread colonic involvement? bloody diarrhoea + clinical features of dehydration & electrolyte imbalance
systemic sx? malaise, anorexia, low grade pyrexia
- OE? normal…severe abdo pain???? suspect toxic megacolon etc!! will show sings of peritonism
- extra intestinal features : msk (?), skin (?), eyes (?), HPB (?)

27
Q

UC differentials?

A
crohns
chronic infections (eg?x3)
mesenteric ischaemia 
radiation colitis 
CA
IBS
coeliac
28
Q

UC investigations ?

A
  • bloods - ?
  • faecal calprotectin
  • stool sample sent for MC&S
  • colonoscopy w biopsy
  • acute exacerbation? AXR or CT to assess for toxic megacolon or perf
    typical AXR features?x3
29
Q

UC management ?

A
  • medical: gastroenterologist. inducing remission : corticosteroid + immunosuppressive therapy. maintain remission: immunosuppressive eg mesalazine, >10 yr of disease + >1 segment affected? colonoscopy due to inc CA risk, IBD nurse specialist
  • surgical : indications for acute surgical treatment: refractory to med management, toxic megacolon, bowel perf. typically require segmental bowel resection & defunctioning stoma (why/). elective? total proctocolectomy (w end ileostomy) is curative but disease control: IRA or panprctocolectomy w IPAA
30
Q

VOLVULUS what is it?

A

twisting of a loop of intestine around its mesenteric attachment resulting in a closed loop bowel obstruction. affected bowel can become ischaemic due to compromised blood supply leading to necrosis & perf

31
Q

VOLVULUS most common site?

A

sigmoid - long mesentery (inc w age) means this portion is more prone to twisting on its mesenteric base.
other common places?

32
Q

VOLVULUS risk factors?

A

inc age, neuropsychiatric disorders, nursing home resident, chronic constipation or laxative use, male, prev abdo ops

33
Q

VOLVULUS clinical features?

A

pt presents w bowel obstruction

  • colicky pain, abdo distension, absolute constipation, vomiting (later on, why?)
  • rapid onset (?), high degree of abdo distension
34
Q

VOLVULUS OE?

A
  • abdo is tympanic to percussion

- examine for signs of perf or peritonism!!

35
Q

VOLVULUS differentials?

A
  • alternative causes for bowel obstruction
  • severe constipation
  • severe sigmoid diverticular disease
36
Q

VOLVULUS investigations ?

A
  • bloods - ?
  • CT AP w contrast - what does it identify ? it’ll show very dilated sigmoid w a ? sign from the twisted mesentery
  • AXR shows ? sign in the LIF. if ileocaecal valve incompetent?
37
Q

VOLVULUS management?

A
  • conservative: decompression by sigmoidscope (describe this process) & insertion of a flatus tube (what is this?)
  • surgery (hartmanns) is indicated if: there’s colonic ischaemia or perf, there were repeated failed attempts @ decompression or there was necrotic bowel noted @ endoscopy.
38
Q

VOLVULUS comps?

A
  • immediate: bowel ischaemia, perf

- long term: risk of recurrence, stoma comps

39
Q

VOLVULUS caecal vs sigmoidal

A

https://www.google.co.uk/url?sa=i&url=https%3A%2F%2Ftwitter.com%2Fdrkeithsiau%2Fstatus%2F1377040460439453699&psig=AOvVaw36ZQvykNvaVALtbehI0oyB&ust=1649338835277000&source=images&cd=vfe&ved=0CAoQjRxqFwoTCLiwqI3I__YCFQAAAAAdAAAAABAD