Large Bowel🥳 Flashcards
APPENDICITIS pathophysiology?
- normally direct luminal obstruction (by what?). also by lymphoid hyperplasia, impacted stool or rarely appendiceal/caecal tumour
- now commensal bacteria multiply leading to acute inflammation
- also reduced venous drainage
- both lead to inc pressure in appendix -> ischaemia
- untreated? necrosis … perforation
APPENDICITIS risk factors?
- FHx : ?% risk?
- ethnicity : more common in? greater risk of perf in?
- environmental: during what season is common?
APPENDICITIS clinical features?
- abdo pain. peri umbilical (dull & poorly localised - why?) —> RIF (sharp & well localised - why?)
- vomiting (before or after pain?)
- anorexia
- nausea
- diarrhoea/constipation
APPENDICITIS on examination?
- rebound tenderness & percussion pain & guarding over McBurney’s point (where is this?)
- severe? sepsis signs eg ?
- *appendiceal abscess may also present w RIF mass
APPENDICITIS specific signs on examination?
- rovsings sign - RIF pain on palpation of ?
- psoas sign - RIF pain with extension of right ? (suggests retrocaecal appendix)
APPENDICITIS differential diagnoses?
- gynae: ovarian cyst rupture, ectopic, PID
- renal: ureteric stones, UTI, pyelonephritis
- GI: IBD, meckel’s diverticulum, diverticula disease
- urological: testicular torsion, epididymo-orchitis
- **specifically in children? gastroenteritis, constipation, intussusception or UTI
APPENDICITIS lab tests?
- urinalysis- why? when can leukocytes be present in the urine still?
- preg test
- bloods - fbc, crp
APPENDICITIS imaging?
clinical diagnosis is normally sufficient.
if clinical features inconclusive:
- USS - first line (especially transvaginal if other gynae pathology differentials). why is it good in kids?
- CT
APPENDICITIS management?
- definitive treatment : laparoscopic appendicectomy
- maybe conservative antibiotic therapy in uncomplicated appendicitis
APPENDICITIS complications?
- perf -> peritonitis
- surgical site infection
- appendix mass - what is this?
- pelvic abscess - presents as palpable RIF mass, confirmed w CT, management?
DIVERTICULAR DISEASE information
- diverticulum = outpouching through bowel wall. common in sigmoid 4 manifestations of this condition: - diverticulosis - ? - diverticular disease - ? - diverticulitis- ? - diverticular bleed - ? - M>F, developed countries
DIVERTICULAR DISEASE pathophysiology
aging bowel has become weakened over time -> stool inc luminal pressure -> results in outpouching of the mucosa through the weaker areas of the bowel wall
…
bacteria can overgrown in the outpouchings leading to inflammation. they can perf leading to diffuse peritonitis sepsis
…
chronic? fistula can form. what ones are most common?x2
…
diverticulitis is either simple (?) or complicated (?)
DIVERTICULAR DISEASE risk factors?
inc age, low dietary fibre, obesity, smoking, fhx, nsaid use
DIVERTICULAR DISEASE diverticulosis clinical features?
asymptomatic and found incidentally on ct or routine colonoscopy
DIVERTICULAR DISEASE clinical features?
intermittent lower abdo pain - colicky in nature & relieved by defecation
other sx: altered bowel habit, associated nausea, flatulence. no systemic features