Lange Q&A Adult Psychopathology Flashcards

(43 cards)

1
Q

Prevalence of schizophrenia in the general population

A

1%

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2
Q

Schizophrenia monozygotic concordance rate

A

50%

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3
Q

Hallmark of Cotard syndrome

A

Psychotic/delusional theme that internal organs have been removed or are malfunctioning.

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4
Q

Folie à deux

A

A shared delusion aroused in someone via the influence of another person

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5
Q

Hallmark of Capgras syndrome

A

People have been replaced by identical appearing imposters (robots, aliens, etc)

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6
Q

Most common etiology of post-partum psychosis?

A

Bipolar disorder

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7
Q

Early sign of schizophrenia during the prodromal period

A

Progressive social withdrawal

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8
Q

Schizophreniform vs. schizophrenia

A

Schizophreniform = 1 - 6 months of symptoms that meet criteria for schizophrenia. Schizophrenia is > 6 months.

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9
Q

Common defense mechanisms utilized in patients with borderline personality disorder

A

Primitive defense mechanisms: denial, projective identification and splitting.

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10
Q

Bleuler’s 4 A’s of schizophrenia

A

Association, Affect, Ambivalence and Autism

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11
Q

Classic features of catatonia

A

Negativism, hypomotorism, echolalia and echopraxia.

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12
Q

Factors that differentiate delusional disorder from schizophrenia?

A

Nonbizzare delusions, lack of hallucinations, negative symptoms and disorganization.

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13
Q

Indications for ECT in major depression

A

High severity of symptoms, history of poor response to many medications and need for quick reversal of symptoms.

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14
Q

Most common sleep disturbance in patients with depression?

A

Early morning awakening

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15
Q

Biochemical changes observed in depression?

A

Increased cortisol. Decreased catecholamines, sex hormones and immune funtion.

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16
Q

Psychiatric illness with strongest genetic predisposition

A

Bipolar I disorder. 1st degree relatives have a 25% chance of getting any type of mood disorder.

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17
Q

Medical illness that commonly presents with psychiatric symptoms and abdominal pain.

A

Porphyria. Rule this out by checking urinary porphobilinogen.

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18
Q

Most common psychiatric illness that presents with visual hallucinations

19
Q

Klüver-Bucy syndrome

A

Severe damage to or disconnection of the amygdala resulting in docility, lack of fear, anterograde amnesia, hyperphagia and hypersexuality.

20
Q

Pick disease

A

Frontotemporal dementia

21
Q

Möbius syndrome

A

Congenital absence of facial nerves and nuclei resulting in bilateral facial paralysis

22
Q

Function of superior temporal gyri

A

Processing auditory information to understand language

23
Q

Treatment of choice of panic disorder with or without agoraphobia

A

Fluoxetine. SSRIs are as effective as benzodiazepines and do not have the addictive or withdrawal effects.

24
Q

% of patients with depression who will have an abnormal dexamethasone suppression test?

A

50%. This is thought to be due to abnormal feedback control in the H-P-A axis due to depression. Note that this is even more prevalent in depressed patients with psychotic features.

25
% of patients who with depression who do not show an increase in TSH after TRH administration
30%
26
Differentiate schizoid from avoidant personality disorder.
In schizoid, patients do not mind the lack of social interaction. In avoidant, the lack of social interaction is distressing to the patient.
27
Dosage of methadone necessary to suppress opioid cravings.
At least 60mg/day
28
Next step in a woman with post-partum psychosis
Hospitalization, this is a psychiatric emergency due to risks to the fetus.
29
Common side effects associated with TCAs
Dry mouth, dizziness (with hypotension) and urinary hesitancy secondary to anticholinergic and adrenergic blockade.
30
Common side effects associated with SSRIs
GI upset, sexual dysfunction and agitation
31
Common side effects associated with Lithium
Polyuria, polydipsia, tremor and confusion
32
Common side effects of divalproex sodium
GI upset, sedation and tremor
33
What causes frontal suclal widening on MRI?
Cerebral atrophy
34
What causes hypointensities in subcortical areas on MRI?
Lacunar stroke
35
What causes cerebellar atrophy on MRI?
Congenital disorders and alcoholism
36
What differentiates dependence from abuse?
The inability to quit using regardless of a desire to quit or knowledge of its negative aspects = dependence.
37
Most common lab abnormality seen in alcoholics?
Elevated GGT. Increases in AST/ALT, uric acid, MCV and triglycerides are also seen.
38
Duration required for classification as a brief psychotic disorder? Schizophreniform? Schizophrenia?
1 day to 1 month = brief psychotic disorder. Schizophreniform = 1 month to 6 months. Schizophrenia > 6 months.
39
5 constructs to consider when assessing a patient for PTSD?
History of a traumatic event, intrusions, avoidance, increased arousal and negative mood/cognitive alterations.
40
Lifetime incidence of suicide in schizophrenia
10%
41
Best treatment for patients with borderline personality disorder?
Psychotherapy and steady social support
42
Average number of ECT treatments to see positive results in patients with catatonic conditions? MDD? Psychosis/mania? When does memory impairment occur?
Catatonic conditions = 2-4 treatments MDD = 6-12 treatments Psychosis/mania = > 20 treatments Memory impairment occurs around 20-40 treatments.
43
Differentiate OCD from OC personality disorder
``` OCD = intrusive obsessions and compulsions that function to decrease anxiety/obsessions. OCPD = clean freak, orderly, stingy, can't complete projects ```