Lange - Chap 4 - Abdomen Flashcards
AST
liver cell necrosis due to
- viral hepatitis
- toxic hepatitis
- acute hepatitis
ALT
-used to assess jaundice with hepatocellular disease
ALP (Alk-Phos)
-When bile excretion is impaired (obstruction of the bile ducts)
Ammonia
hepatocellular disease
AFP
- Monitor chemo treatment
- prenatal mothers for neural tube defects
Bilirubin
> Direct- obstruction
Indirect- anemia and liver disease
Total- Hepatitis and mets
Hematocrit
Drop in hematocrit indicates bleeding - likely due to trauma
Leukocytosis
Inc in WB indicates an inflammatory process or abscess
PT
Decrease in PT can cause uncontrolled hommorrhage
clotting time is longer in pts with acute cholecystitis, GB carcinoma and CBD obstruction
Urinary bile/bilirubin
- obstructive liver disease
- bilirubin alone = excessive amount of RBC destruction
Urinary urobilinogen
Complete obstruction of biliary tract vs incomplete obstruction of biliary tract
>increase = liver disease or infection
>no excessive amt in urine = complete biliary tract obstruction
Fecal urobilinogen
>increase = hemolysis >decrease = complete destruction
WBC
increase = infection (cholecystitis, cholangitis, etc.)
Serum Bilirubin
Increases with obstruction or GB carcinoma
Amylase
Acute Pancreatitis: Increase within the first 24 hours