Lambert Eaton Syndrome Flashcards
1
Q
What is another name for Lambert-Eaton Syndrome?
A
Masthenic-myopathic syndrome
2
Q
What condition is Lambert Eaton Syndrome typically associated with?
A
Small cell lung carcinoma
3
Q
Describe the mechanism leading to Lambert-Eaton Syndrome
A
IgG Abs produced against the small cell lung cancer cross react with voltage-sensitive calcium channels expressed in motor nerve terminals. These channels are required for ACh release.