Lambert Eaton Syndrome Flashcards

1
Q

What is another name for Lambert-Eaton Syndrome?

A

Masthenic-myopathic syndrome

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2
Q

What condition is Lambert Eaton Syndrome typically associated with?

A

Small cell lung carcinoma

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3
Q

Describe the mechanism leading to Lambert-Eaton Syndrome

A

IgG Abs produced against the small cell lung cancer cross react with voltage-sensitive calcium channels expressed in motor nerve terminals. These channels are required for ACh release.

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