Labs Flashcards
1
Q
Discuss urea/creatinine ratio
A
Urea and creatinine are both freely filtered at the glomerulus,
- creatinine is not reabsorbed,
- urea reabsorbed by tubules via regulation
In the setting of renal failure a ratio of
40-100:1 - normal or post renal cause of AKI
->100:1 - pre-renal causes
<40:1 intrinsic renal damage (urea unable to be absorbed)
2
Q
Discuss causes of increased urea/creatinine ratio (Drivers can use GPS)
A
Dehydration Corticosteroids GI haemorrhage protein rich diet severe catabolic state
3
Q
Dicsuss causes of decreased ruea:creatinine ratio (i am a simple SR)
A
Severe liver disease Intrinsic renal damage malnutrition pregnancy low protein diet SIADH Rhabdomyolysis
