Labour, Delivery and Analgesia Flashcards

1
Q

When does normal delivery occur?

A

Between 39-41 weeks since date of last menstrual period

Within 24 hours of onset of regular contractions

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2
Q

Describe the first stage of labour

A

The time between the onset of regular contractions, until the cervix is fully dilated
Latent phase is when the cervix is less than 4cm dilated, and not yet fulled effaced
Active phase is between 4-10cm dilated and cervix is fully effaced

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3
Q

What is effacement

A

The change in the shape of the cervix from ‘bulbed’ to flat

- balloon demonstration

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4
Q

Describe the second stage of labour

A

Between complete dilation of the cervix, and birth of the baby
- normally takes between 15-120 mins

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5
Q

Describe the third stage of labour

A

Delivery of the placenta and membranes

- control of bleeding

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6
Q

Describe the mechanisms of labour

A

Engagement (in the occipito-transverse position, the fetal head entered the pelvis)
Decent and flexion of the head as it aligns with the pelvic gutter
Internal rotation occurs as the gutter forces the fetal head to turn 45 degrees, so the baby is facing posteriorly
- shoulders remain occipito-transverse
Extension of the fetal neck occurs as the head passes under the symphysis pubis, and the head is delivered
Restitution (external rotation) occurs once the head is delivered (occipito-anterior), and realigns with the shoulders (occipito-transverse)
Expulsion is delivery of the shoulder and rest of the fetus
- anterior shoulder first, then posterior

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7
Q

How is labour diagnosed

A

Regular painful contractions in the presence of an effaced cervix (which is 3cm or more dilated)
Contractions are identified by palpation and identification on CTG

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8
Q

Clinical assessment of labour

A
Palpation of contractions 
- strength
- timing
- length
CTG - only information regarding the timings of contractions, not strength 
Vaginal examination 
- bishop's score 
- dilatation
- effacement
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9
Q

What is a partogram

A

Composite graphical record of key data (maternal and fetal) during labour
Components
1) patient ID
2) time, recorded at intervals of one hour
3) fetal heart rate (every 30 mins)
4) state of membranes and colour of liquid
5) cervical dilation and decent of head
6) uterine contractions (duration and intensity)
7) drugs and fluids
8) blood pressure every 2 hours
9) pulse rate every 30 mins
10) oxytocin
11) urine analysis
12) temperature

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10
Q

What are the components of a Bishop’s score

- used for cervical assessment

A
Cervical dilatation
Length of cervix
Station of presenting part
Consistency
Position 

The higher the score, the more likely labour will begin without induction

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11
Q

Differences between a pregnant and non-pregnant uterus

A
Non-pregnant
- 6-8cm long
- 5cm wide
- walls 2cm thick
- 70g
Pregnant 
- cellular hyperplasia and hypertrophy 
- 4-5 x enlarged 
- 1000g
- accommodates 5 litres
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12
Q

Describe the balance of forces that keep the fetus in-utero until term, and the balance of forces that allow delivery of the infant at term

A
Fetus kept in-utero because 
- high cervical resistance 
- low muscular corpus expulsive forces
Fetus delivery because 
- low cervical resistance
- high muscular corpus expulsive force
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13
Q

Describe the differences between the uterine cervix and the uterine corpus

A
Uterine cervix 
- sparse contractile myocytes
- high fibrous connective tissue (provides tensile strength)
- type 1 and type 3 collagen 
Uterine corpus
- parametrium
- myometrium (muscle)
- endometrium (ciliated columnar epithelium)
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14
Q

Describe the myometrium

A

Provides the tissue which allows the uterus to contract

  • mainly myocytes
  • also connective tissue, blood vessels, lymphatic vessels and nerves
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15
Q

What are the two main hormones that modulate contractile activity

A

Oxytocin

Prostaglandin

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16
Q

What is oxytocin used for in labour

A

IV infusion of synthetic oxytocin is used to induce labour by stimulating contractions
After amniotomy
Risk of tonic contraction

17
Q

What are prostaglandin, and how are they used in labour

A

They are uterotonic and cervical priming hormones
Shown to ripen the cervix when applied topically during the inducation process
Endogenous prostaglandin can also stimulate myometrial contractility
Risk of uterine hyperstimulation

18
Q

What is tocolysis

A

In pre-term labour, attempts at reversal of uterine activity can be made
- this is mainly to allow the administration of steroids, which aid the development of fetal lung maturation
- may also allow transfer to another hospital that offers neonatal care
No method has been proven safe
- none show an improvement in neonatal mortality or morbidity

19
Q

Which tocolytic agents are used in clinical practice

A

Beta-agonists e.g. ritodrine
- most common agent in UK
acts on beta-receptors in myometrium to cause relaxation
- SE of pulmonary oedema can be fatal
Calcium-channel blockers e.g. nifedipine
- blocks calcium channels in the myometrium, interrupting contractions
- may alter uteroplacentral blood flow
Oxytocin receptor antagonists e.g. atosiban
- delays delivery with the least SE for mother and fetus
- very expensive
Magnesium Sulphate
- Competes at calcium channels in the myometrium
- linked to increased neonatal mortality
NSAIDs e.g. indomethacin
- acts on the COX enzyme that catalyses prostaglandin production
- drug with highest SE for fetus

20
Q

Definition of pre-term birth

A

Birth occuring at <37 completed weeks gestation

21
Q

Risk factors for pre-term birth

A
Maternal stress
Maternal BMI
Maternal age
Antepartum heamorrhage 
Socio-economic status 
Alcohol/cigarettes/recreational drugs 
Maternal infection 
Maternal ethnicity - afro-caribbean 
Family/personal history
Multiple pregnancy
22
Q

Complications of pre-term birth

A
Respiratory distress syndrome 
Transient tachypnoea 
Chronic lung disease 
Pneumonia 
Apnoea and bradycardia 
Infection 
Jaundice 
Intraventricular haemorrhage
Inability to maintain body heat
Immature GI system 
Inguinal hernia 
Anaemia 
Patent ductus arteriosus 
Retinopathy of prematurity
Necrotising Enterocolitis 
Sepsis  
Developmental diability 
Cerebral palsy 
UTI
23
Q

Describe the role of steroids in the management of pre-term delivery

A

Corticosteroids can be administered in order to boost fetal lung surfactant producation and therefore reduce fetal respiratory distress
- two IM injections 12 hours apart
Recommended in women in threatened pre-term labour between 24 and 36 weeks gestation

24
Q

Define a postdates pregnancy

A

Pregnancy after 40 weeks gestation (after then estimated date of delivery)
Post-term
- pregnancy after 42 weeks gestation (EDD +14 days)

25
Q

Clinical problems of post-date pregnancy for the mother

A
Intrapartum C-section 
Instrumental delivery 
Perineal trauma and injury 
Post-partum haemorrhage
Longer
Analgesic requirement increased
Psychological distress 
Uterine hyperstimulation and rupture
26
Q

Clinical problems of post-date pregnancy for the baby

A

Stillbirth (antepartum and intrapartum)
Perinatal death and morbidity from meconium aspiration
Shoulder dystocia
Intrapartum C-section
Behavioural and emotional problems as a child

27
Q

What are the two main problems with dysfunctional activation in labour

A

Dysfunctional labour - failure to progress

Atonic post-partum haemorrhage

28
Q

Describe dysfunctional labour

A
Poor uterine contractility 
Clinically
- slow progression of labour
- assisted vaginal delivery more likely 
- intrapartum C-section more likely (half of emergency C-sections despite over 80% receiving syntocinon)
29
Q

Describe atonic post-partum haemorrhage

A

Failure of contraction mechanisms after delivery
Clinically
- excessive blood loss (>500ml)
- 6th leading cause of maternal mortality in UK

30
Q

What are the common causes of dysfunctional activation

A
Parity
Maternal age
Maternal BMI
Birth weight and uterine wall tension 
Previous mode of delivery 
Genetics
31
Q

Describe visceral pain in labour

A
Relating to the uterus 
Felt in first stage of labour 
Due to progressive mechanical dilation of cervix  and lower segment = transient ischaemia of myometrium
T10 to L1
Dull in character
Sensitive to opioids
32
Q

Describe somatic pain in labour

A

Pain relating to non-uterine tissues
Felt in late 1st stage and 2nd stage
Due to stretching and distension of the pelvic floor, perineum and vagina
S2 to S4
- peudendal nerve and perineal branches of the post-cutanous nerve of the thigh

33
Q

What are the non-pharmacological analgesia options during labour

A
Maternal support 
Environment 
Birthing pools
Education
TENS machine
34
Q

Pharmacological analgesia options during labour

A
Oral analgesia
Inhaled entonox (50:50 oxygen and nitrous oxide) 
Systemic opioids 
Remifentanil PCA
Peudendal analgesia 
Epidural anaesthesia 
Spinal anaesthesia 
General anaesthesia
35
Q

Describe the use of epidural anaesthesia during labour

A

Provides analgesia for labour, and can be ‘topped-up’ for C-section
Extradural catheter placement
Cannula allows top-up for prolonged use
Analgesia effect may be patchy

36
Q

Describe the use of spinal anaesthesia during labour

A

Used for operative procedures
Subarachnoid injection
One off injection lasting 2-4 hours
Dense and relatively reliable anaesthetic blockade

37
Q

Describe the use of general anaesthesia during labour

A

Increased risk

  • gastric aspiration and pneumonitis
  • failed or difficult intubation and ventilation (caused by pregnancy related obesity, laryngeal oedema or large breasts)