Labour And Delivery

Question 1

What is the absolute risk of encephalopathy with seizures with a umbilical cord pH below 7.0?

Answer 1

2.95%

Question 2

What is the sensitivity and specificity of fetal lactate?

Answer 2

Sensitivity 67% and specificity 93% in predicting moderate to severe HIE

V’s

Fetal pH - sensitivity 49% and specificity 93%

Question 3

What are the threshold values for fetal lactate to prevent moderate to severe HIE and to prevent a Apgar score of <4 at 5 mins?

Answer 3

<4.2 - normal
4.2-4.8 - pre acidaemia (repeat 20-30mins later)
> 4.8 - acidaemia - consider delivery

Question 4

What is the incidence of cerebral palsy in specific gestational ages?

Answer 4

14. 6% 22-27/40
15. 2% 28-31/40
16. 7% 32-36/40
17. 1% term infants

Question 5

What proportion of cerebral palsy infants born pre term?

Answer 5

25% of all cases of CP are in infants born <34/40

Question 6

What is the most common pathological lesion associated with cerebral palsy?

Answer 6

Peri ventricular white matter injury

Question 7

What is the reduction in CP when mothers administered with magnesium sulphate in pre term labour?

Answer 7

Magnesium sulphate given to women at risk of pre term birth reduced risk of CP by 32%