Laboratory: Blood Vessel Diseases & Heart Flashcards
Diagnosis
Myocardial Infarct 48 hours
What is the Doagnosis?
Necrotizing Vasculitis
a. Diagnosis
b. What mutation?
c. What part is the mutation
a. Hypertrophic Cardiomyopathy
b. Beta myosin heavy chain
c. Sarcomere mutation
a. What is the Diagnosis
b. What type of Inflammation?
a. Giant Cell Arteritis
b. Granulomatous Inflammation
a. Diagnosis
b. What is present in granulation tissue formation?
a. Myocardial Infarct 8-10 days
b. BLood vessels, fibrosis, mononuclear cell infiltrates
Diagnosis
Myocardial Infarct 1 month after
Diagnosis
Myocardial Infarct 8-10 days
a. Diagnosis
b. Describe fiber
a. Myocardial Infarct after 72 hours
b. Disintegrated Muscle Fiber
a. Diagnose
b. Where does it reside
a. Cardiac Myxoma
b. Atrium
- Polyp residing in chambers, more on ATRIUM
- Uncommon
- Associated in familial forms in 2 sydnromes
1.Mazabraud’s syndrome
- GNAS1 mutation
- Associated with fibrousdysplasia
2.Carney’s Syndrome/triad
•Presence of myxoma, skin hyperpigmentation, endotheliapathies
a. Diagnosis
b. Responsible for the acceleration of this disease
c. Stain used?
a. Amyloidosis
b. Transthyretin Deposition
c. Congo red stain, Use polarizing microscope
a. What is the diagnosis?
b. Type II is seen in?
a. Necrotizing Vasculitis
b. ANCA (Antineutrophil cytoplasmic antibodies)
a. What is the diagnosis?
b. Type of necrosis present
a. Myocardial Infarct 48 hours
b. Coagulative necrosis
a. What is the diagnosis
b. What is this identified with?
a. Cystic Medial Necrosis
b. Aortic Dissection/
Marfan Syndrome
a. What is the Diagnosis?
b. What part of the tunica is degenerated?
c. What enzyme does it contain which is responsible for the separation of muscle fibers, thus weakening the media?
d. Describe the appearance
a. Cystic Medial Necrosis
b. Tunica Media
c. Hyaluronidase
d. Basophilic Appearance
a. Diagnosis
b. Cause
a. Bacterial Endocarditis
b. S. Aureus
presence of destructive vegetations especially if endocarditis is caused by Staphylococcus Aureus
•S. Aureus
culprit of Acute Infective Endocarditis;
destroys NORMAL VALVES
Difficult to treat with antibiotics (do surgery)
S. viridans and other minor
Culprit of Subacute Infective Endocarditis
Affect only DAMAGED VALVES (prosthesis, signs of regurgitation)
a. Diagnosis
b. What causes this disease?
a. Bacterial Endocarditis
b. S. Aureus
- presence of destructive vegetations especially if endocarditis is caused by Staphylococcus Aureus
- •S. Aureus
- culprit of Acute Infective Endocarditis;
- destroys NORMAL VALVES
- Difficult to treat with antibiotics (do surgery)
- S. viridans and other minor
- Culprit of Subacute Infective Endocarditis
- Affect only DAMAGED VALVES (prosthesis, signs of regurgitation)
a. Diagnosis
b. Etiology
a. Chronic Passive Congestion, Lung
b. Left Sided Heart Failure
Diagnosis
Amyloidosis
Diagnose
CArdiac myxoma
Polyp residing in chambers, more on ATRIUM
- Uncommon
- Associated in familial forms in 2 sydnromes
1.Mazabraud’s syndrome
- GNAS1 mutation
- Associated with fibrousdysplasia
2.Carney’s Syndrome/triad
•Presence of myxoma, skin hyperpigmentation, endotheliapathies
Diagnosis
Myocardial Infarct 8-10 days
a. Diagnosis
b. Identify cell pointed
a. Myocardial Infarct 1 month after
b. Hemosiderin-laden macrophage
a. Diagnosis
Constrictive Pericarditis
a. Diagnosis
b. What is the nuclear change present?
a. Myocardial Infarct 48 hours
b. Karyolysis
a. What is the Diagnosis
b. What part of the organ
c. Describe the picture
a. Aortic Dissection
b. False lumen of the Aorta
c. Pooling of Blood
Diagnosis
Myocardial Infarct 6 months
a. What is the diagnosis
b. Describe the Organ
a. Aortic Dissection
b. Double barreled Aorta
What is the diagnosis?
THROMBOSIS
(Older Thrombus)
a. Diagnosis
b. What evidence is seen in this slide
a. Myocardial Infarct after 72 hours
b. reperfusion
a. What is the diagnosis?
b. What cells are usually seen in this slide?
a. Cutaneous Vasculitis
b. Neutrophils
a. Diagnosis
b. Etiology
c. Identify Cell Pointed
d. Cause
a. Constrictive Pericarditis
b. Tuberculosis
c. Langhan’s type Giant Cell
d. Granuloma
Diagnosis
Myocardial Infarct 1 month after
Diagnosis
Myocardial Infarct 8-10 days
Diagnosis
Myocardial Infarct after 72 hours
What is the diagnosis?
THROMBOSIS
(Older Thrombus)
What is the diagnosis?
THROMBOSIS
(Older Thrombus)
What is the diagnosis?
THROMBOSIS
New Thrombus
a. What is the diagnosis
b. Identify Red box part
c. Identify Blue box part
a. Aortic Dissection
b. True Lumen
c. False Lumen
What is the diagnosis?
THROMBOSIS
(NEW THROMBUS)
Diagnosis
Hypertrophic Cardiomyopathy
a. Diagnosis
b. What tissue
c. Etiology?
b. Constrictive Pericarditis
b. Pericardial Tissue
c. Tuberculosis
Diagnosis
Myocardial Infarct 8-10 days
a. Diagnosis
b. Identify the one pointed
a. Giant Cell Arteritis
b. Epithelioid Histiocytes
a. What is the diagnosis?
b. Identify the one pointed.
a. THROMBOSIS
(New Thrombus)
b. Monckeberg’s Calcific Sclerosis
a. What is the diagnosis?
b. What type of necrosis?
a. Cutaneous Vasculitis
b. Fibrinoid Necrosis
a. Diagnosis
b. Earliest sign of infarction?
a. Myocardial Infarct 48 hours
b. waviness of fiber
a. Diagnose
b. Identify Cell pointed
c. Etiology
a. Chronic Passive Congestion, Lung
b. Hemosiderophage/ Heart failure cell
c. Left Sided Heart Failure
