Lab Values & Monitoring Flashcards
Calcium normal range (total)
8.5-10.5 mg/dL
Calcium normal range (ionized)
4.5-5.1 mg/dL
When to calculate corrected calcium?
When albumin is low (<3.5 g/dL)
Calculate corrected calcium with ionized Ca?
No
Ca correction equation
Ca (mg/dL) = calcium(reported) + [4.0 - albumin) * (0.8)]
Drugs that ↑ Ca?
calcium supplementation, vitamin D, thiazide diuretics
Drugs that ↓ Ca?
long-term heparin, loop diuretics, bisphosphonates, cinacalcet, [systemic steroids, calcitonin, foscarnet, topiramate]
Magnesium normal range
1.3-2.1 mEq/L
Reasons for ↓ Mag?
PPIs, diuretics, [amphoB, foscarnet, echinocandins, diarrhea, chronic alcohol use]
Phosphate normal range
2.3-4.7 mEq/dL
Reasons for ↓ PO4?
[phosphate binders, foscarnet, oral Ca intake]
Reasons for ↑ PO4?
renal failure
Potassium normal range
3.5-5 mEq/L
Reasons for ↑ K?
ACEis, ARBs, aldosterone receptor antagonists, aliskiren, canagliflozin, CYA, tacrolimus, MMF, K supplements, SMZ/TMP, drospirenone, chronic heparin use, NSAIDs, pentamidine
Reasons for ↓ K?
b-2 agonists, diuretics, insulin
Sodium normal range
135-145 mEq/L
Reasons for ↓ Na?
carbamazepine, oxcarbazepine, SSRIs, diuretics
Bicarbonate normal range (venous/arterial)
venous: 24-30 mEq/L
arterial: 22-26 mEq/L
Reasons for ↓ Bicarb?
topiramate
Blood Urea Nitrogen normal range (BUN)
7-20 mg/dL
Serum creatinine normal range
0.6-1.3 mg/dL
Reasons for ↑ SCr?
aminoglycosides, amphoB, cisplatin, colistimethate, CYA, loop diuretics, polymixin, NSAIDs, radiocontrast dye, tacrolimus, vancomycin
Anion Gap normal range
5-12 mEq/L
Reasons for ↑ AG?
metabolic acidosis
WBC normal range
4,000-11,000 cells/m^(3)
Neutrophils normal range
45-73%
Bands normal range
3-5%
What are bands?
immature neutrophils released to fight infections (left shift)
Eosinophils normal range
0-5%
Cause for high eosinophils?
parasitic infections
Basophils normal range
0-1%
Cause for high basophils?
hypersensitivity reactions
Lymphocyte normal range
20-40%
Causes for high lymphocytes?
viral infections, lymphoma
Causes for low lymphocytes?
bone marrow suppression, HIV due to systemic steroids
RBC normal range (males)
4.5-5.5 * 10^(6) cells/uL
RBC normal range (females)
4.1-4.9 *10^(6) cells/uL
Hgb normal range (males)
13.5-18 g/dL
Hgb normal range (females)
12-16 g/dL
MCV normal range
80-100 fL
Causes for high MCV?
B12 or folate deficiency
Causes for low MCV?
iron deficiency
Folic acid normal range
5-25 mcg/L
When are folic acid levels ordered?
To differentiate macrocytic anemia
Causes for low folic acid?
phenytoin/fosphenytoin, phenobarbital, primidone, methotrexate, SMX/TMP
B12 normal range
> 200 pg/mL
Causes for low B12?
PPIs, metformin
reticulocyte count normal range
0.5-2.5%
Positive Coombs test?
drug-induced hemolysis caused by penicillins and cephalosporins, dapsone, isoniazid, levodopa/methyldopa, methylene blue, nitrofurantoin, etc
G6PD normal range
5-15 units/gram
Anti-Xa activity normal range
1-2 IU/mL
When to obtain peak anti-Xa?
4 hours after SC LMWH dose
PT normal range
10-13 seconds
INR normal range
<1.2
INR goal range for anticoagulated patients
2-3 (2.5-3.5 for mechanical heart valve)
Platelet normal range
150,000-450,000 mm^(3)
Albumin normal range
3.5-5 g/dL
AST/ALT normal range
10-40 units/L
T Bili normal range
0.1-1.2 mg/dL
Amylase normal range
60-180 units/L
Lipase normal range
5-160 units/L
CPK normal range (males)
55-170 IU/L
CPK normal range (females)
30-135 IU/L
Troponin I normal range
0-0.5 ng/mL
BNP normal range
<100 pg/mL
LDL normal range
<100 mg/dL
HDL normal range
≥ 60 mg/dL
Non-HDL calculation
TC-HDL
TG normal range
<150 mg/dL
CRP normal range
0-0.5 mg/dL
Fasting Plasma Glucose for diabetes
≥ 126 mg/dL
Fasting Plasma Glucose for prediabetes
100-125 mg/dL
A1c normal
<7% ADA
C-peptide (fasting) normal range
- Used to distinguish T1DM vs T2DM
- 0.78-1.89 ng/mL
Thyroid-stimulating hormone normal range
0.3-3 MlU/L
TSH level for HYPOthyroidism
increase
TSH level for HYPERhyroidism
decrease
Uric acid normal levels (males)
3.5-7.2 mg/dL
Uric acid normal levels (females)
2-6.4 mg/dL
CD4+ T lymphocyte count normal
800-1,000 cells/m^(3)
HIV RNA concentration (viral load) normal
undetectable
pH normal level
7.35-7.45
PSA normal level
< 4 ng/mL
lactic acid normal range
0.5-2.2 mEq/L