Lab Values

Question 1

What does AST stand for?

Answer 1

Aspartate Transaminases

Question 2

What does ALT stand for?

Answer 2

Alanine Transaminase

Question 3

What does GGT stand for?

Answer 3

Gamma Glutamyl Transpeptidase

Question 4

What does ANA stand for?

Answer 4

Antinuclear antibody

Question 5

When can ANA be elevated ?

Answer 5

autoimmune conditions (SLE, Hashimotos, hepatitis, myasthenia gravis) or chronic disease. Some meds can elevate it. 98% of pts with SLE will have an elevated ANA.

Question 6

What is Anti- dsDNA (double stranded DNA) used for?

Answer 6

if ANA is +ve, for SLE

Question 7

What is Anti-SM used for?

Answer 7

SLE (30%)

Question 8

What is Anti-RO (SSA) used for?

Answer 8

Sjogrens (70%), SLE, scleroderma, celiac

Question 9

What does Anti-dsDNA stand for?

Answer 9

Anti double stranded DNA

Question 10

What is Anti-LA (SSB) used for? What is it specific for?

Answer 10

Sjogrens (60%), SLE, Scleroderma. Specific for Sjogrens

Question 11

What does Anti- CCP stand for?

Answer 11

Anti cyclic citrullinated peptide

Question 12

What does Anti CCP (anti cyclic citrullinated peptide) test for?

Answer 12

RA

Question 13

What does Anti Jo 1 test for?

Answer 13

polymyositis (20- 30%), pulmonary fibrosis

Question 14

When is complement (both C3/C4) increased ?

Answer 14

Inflammation, CA, UC, thyroiditis, acute MI, sarcoidoses

Question 15

When is complement (both C3/C4) decreased?

Answer 15

hereditary deficiencies, infections, SLE, septicemia (C3 only), kidney disease, cirrhosis/hepatitis, malnutrition