Lab Values Flashcards
What does a BMP include?
electrolytes, glucose, renal function, acid/base
What does a CMP include?
BMP + albumin, ALT, AST, bilirubin, protein
What is the normal range for calcium?
9.5-10.5 mg/dL (correct if albumin is LOW)
What is the normal range for magnesium?
1.3-2.1 mEq/L
What drugs increase calcium?
vitamin D, thiazide diuretics
What drugs decrease calcium?
long-term heparin, loop diuretics, bisphosphonates, cinacalcet
What drugs decrease magnesium?
PPIs, diuretics, amphotericin B, chronic alcohol intake
What is the normal range for phosphate?
2.3-4.7 mg/dL
Which disease state increases phosphate?
CKD
What is the normal range for potassium?
3.5-5 mEq/L
What drugs increase potassium?
ACEi, ARBs, canagliflozin, cyclosporine, tacrolimus, potassium supplements, Bactrim, drospirenone-containing COCs
What is the normal range for sodium?
135-145 mEq/L
What drugs increase sodium?
hypertonic saline, tolvaptan
What drugs decrease sodium?
carbamazepine, oxcarbazepine, SSRIs, diuretics
What drugs decrease potassium?
beta-2 agonists, diuretics, insulin, SPS, steroids
What decreases bicarbonate?
topiramate
What is the normal range of BUN?
7-20 mg/dL
What increases BUN?
renal impairment and dehydration
What increases SCr?
Any drugs that impair renal function (aminoglycosides, amphotericin B, cisplatin, Colistimethate, cyclosporine, loop diuretics, polymyxin, NSAIDs, radiocontrast dye, tacrolimus, vancomycin)
What is the normal range for anion gap?
5-12 mEq/L
What is the normal range for WBCs?
4,000-11,000 cells/mm3
What drugs can increase WBCs?
systemic steroids, Epi
What drugs can decrease WBCs?
clozapine, chemotherapy, carbamazepine, immunosuppressants
What can increase esoinophils?
asthma, inflammation, parasitic inflammation
What can increase basophils?
inflammation, hypersensitivity rxn
What can increase lymphocytes?
viral infections, lymphoma
What can decrease lymphocytes?
bone marrow suppression, HIV, systemic steroids
What is the normal range for hemoglobin? (male and female)
13.5-18 g/dL (males) and 12-16 g/dL (females)
What disease-state increases MCV (mean corpuscular volume)?
macrocytic anemia (B12 or folate deficiency)
What disease-state decreases MCV (mean corpuscular volume)?
microcytic anemia (iron deficiency)
What is the normal range for folic acid (folate)?
5-25 mcg/L
What drugs decrease folate?
phenytoin, phenobarbital, primidone, methotrexate, Bactrim
What is the normal range for B12?
> 200 pg/mL
What drugs decrease B12?
PPIs, metformin
What drugs cause glucose-6-phosphate dehydrogenase (G6PD) deficiency?
dapsone, methylene blue, nitrofurantoin, pegloticase, primaquine, rasburicase, quinidine, quinine, sulfonamides
What drugs can cause a false increase in PT/INR?
daptomycin, oritavancin, telavancin
What is the lifespan of platelets?
7-10 days
What is the lifespan of RBCs?
120 days
What is the normal range of platelets?
150k-450k cells/mm3
What confirmatory test is used in HIT if the ELISA test is positive?
SRA (serotonin release assay)
What are the pancreatic enzymes?
amylase and lipase
What drugs can cause increases pancreatic enzymes d/t pancreatitis?
didanosine, stavudine, GLP-1a, DPP-4i, valproic acid, hypertriglceridemia
What drugs increase CPK?
daptomycin, statins, tenofovir, raltegravir, dolutegravir
Does TSH increase or decrease in hyperthyroidism?
TSH decreases (< 0.3 mIU/L)
Does TSH increase or decrease in hypothyroidism?
TSH increases (> 3 mIU/L)
What CD4 T lymphocyte count is indicative of an immunocompromised state in HIV?
< 200 cells/mm3
What positive test indicates a pregnancy?
hCG
What is the normal range for Vitamin D, serum?
> 30 ng/mL