Lab Practical 3 Flashcards
Structure of skeletal muscle from microscopic to gross anatomy
Myofilaments (actin/myosin) Myofibrils Fiber Endomysium (CT covers fiber) Fascicles Perimysium (CT covers fascicles) Group of fascicles (muscle) Epimysium (CT covers muscle)
Saltatory conduction
Action potential leaping over parts of myelin sheath to move faster
Muscle fiber
Cells of muscle.
Work together with neuron to allow motion.
Myofibril
Groups of these make a fiber.
Lie below sarcolemma.
Give striped appearance.
Myofilament
Threadlike structures that make up myofibrils.
Actin/myosin proteins.
Allow contraction of muscles.
Banding appearance.
Actin
Thin filament.
Slides past myosin to allow contraction.
Myosin
Thick filament.
Combines with actin to allow muscle contraction.
Aponeurosis
Sheet like CT that attaches muscles to eachother or bones.
Tendon
Strong cordlike.
Provide durability and conserve space.
Can span rough bony parts that would otherwise harm muscle.
Can pass over joints.
Epimysium
Coarse overcoat of dense CT that holds a large group of fascicles together. Aka, covers whole Muscle.
Perimysium
Collagenic membrane that wraps fascicles.
Endomysium
Delicate areolar CT sheath that covers each fiber.
Neuromuscular junction structure
Axon terminal Synaptic end bulbs Skeletal muscle fiber Synaptic cleft Synaptic vesicles Motor end plate
Function of neuromuscular junction in muscle function
Nerve impulse reaches axon terminal.
Synaptic vesicles release acetylcholine (ACh) into synaptic cleft.
ACh diffuse across junction combining with receptors on sarcolemma.
Permeability in sarcolemma changes.
Channels allow both Na and K ions to pass.
More Na diffuses into fiber than K diffuses out so depolarization of sarcolemma happens causing contraction of muscle fiber.
Neuroglia of CNS (brain and spinal cord)
- Astrocyte - create blood brain barrier
- Microglia - phagocytosis
- Ependymal cells - produce cerebrospinal fluid (CSF), help to circulate it
- Oligodendrocyte - produce myelin and wrap it around axons
Neuroglia in PNS
- Schwann cells - produce myelin and wrap it around axons of neurons
- Satellite cells - provide structural support to neurons and regulate exchange of nutrients and wastes to neurons
Dendrites
Receiving end of neuron
Neuron
Nerve cell.
Transmits action potentials/impulses.
Axon
Transmitting end of neuron.
Neuroglia
Serve the needs of the neuron by bracing and protecting them.
Cell body of neuron
Main part from which slender processes extend.
Make up gray matter of nervous system.
Node of ranvier
Gaps in the myelin sheath.
Nissl bodies
Elaborate type of rough endoplasmic reticulum that are involved in the metabolic activities of the cell.
Pyramidal cells found where?
Cerebral cortex.
Purkinje cells found where?
Cerebellar cortex
Epineuriem
Covers a bundle of fascicles (nerve)
Perineurium
Surrounds groups of fibers (fascicles)
Fascicles nerves
Bundles of nerve fibers
Endoneurium
Surrounds each nerve fiber
Functional classes of neurons
- Motor neurons (efferent)- from brain/spinal cord to effectors (muscles/glands)
- Sensory neurons (afferent)- from receptor to brain/spinal cord
- Interneurons (association)- located in brain/ spinal cord; integrate info b/n sensory and motor neurons
Structural classes of neurons.
- Multipolar- most motor neurons; dendrites attached to neuron attached to axon
- Unipolar- sensory neurons; dendrites attached to axon with neuron branching up from body of axon
- Bipolar- rare; found only in special sensory organs like eyes/ears; dendrites attached to line attached to neuron attached to axon.
White matter
Myelinated axons
Gray matter
Cell bodies/ dendrites
4 major regions of brain
- Cerebral Hemispheres (what makes us human)
- 2 hemispheres (R&L)
- 5 lobes
- frontal, parietal, occipital, temporal, insula (limbic)
- 2 hemispheres (R&L)
- Diencephalon
- thalamus, hypothalamus, epithalamus (pineal body) - Brain Stem
- midbrain, pons, medulla oblongata
- Cerebellum
Gyri
Ridges of brain tissue.
Fissure
Deep grooves
Sulci
Shallow grooves that separate gyri
3 meningeal layers
- Dura mater - outermost; periosteal (attached to inner surface of skull forming periosteum) and meningeal (outermost brain covering and continuous with dura mater of spinal cord) layers
- Arachnoid mater - middle meninx; underlies dura mater partially separated by subdural space; tread like projections bridge subarachnoid space to attach to innermost meninx….
- Pia mater - inner most; highly vascular, clings tenaciously to brain surface following its convulsions.
Formation, circulation, drainage of CSF
Choroid plexuses from each ventricle. Lateral ventricles. Interventricular foramen. Third ventricle. Cerebral aqueduct. Fourth ventricle. Either median and lateral apertures or central canal of spinal cord. Either subarachnoid space or filum terminale. Either arachnoid villi or subarachnoid space. Dural sinuses. Venous blood supply. Capillaries and ependymal cells. Repeat.
Arachnoid villi
Specialized projections of the arachnoid tissue that protrude through the dura mater to allow the CSF to drain back into the venous circulation via superior sagittal sinus and other dural sinuses.
Dural sinuses
Venous channels found between dura mater in brain.
Receive blood from internal and external veins of the brain.
Receive CSF from subarachnoid space.
Empty into internal jugular vein.
Longitudinal fissure
Divides 2 hempispheres
Frontal lobe
Mostly motor function, some personality characteristics
Parietal lobe
Sensory
Lateral sulcus
Separates frontal and parietal from temporal
Temporal lobe
Auditory
Occipital lobe
Visual
Central sulcus
Divides frontal and parietal lobes
Precentral gyrus
Primary motor cortex location: all voluntary motor commands start here
Broca’s area
Motor portion of speech; say words
Postcentral gyrus
Primary sensory cortex location: all conscious sensory info goes here
Wernicke’s area
Sensory part of speech: understanding speech
Olfactory bulbs
Sensory info about smell (cranial nerve 1)
Optic nerves
Cranial nerve 2