Lab Part II Flashcards
Which layer(s) of the heart are highlighted? What special structures are included?
Endocardium (epithelium+CT) and subendocardium (btwn endocardium and myocardium); subendo. much thicker here to contain Purkinje fibers
What is the large structure here? Which cardiac layer is it part of?
Major cardiac vessel (filled w/ resin) in subepicardium (adipose + CT)
Name the layers here
Tunica intima (endothelium
Tunica media (elastic lamellae)
Tunica adventitia (external CT)
What are the white squiggles on the inside and outside of the vessel?
Internal + external elastic laminae (muscular arteries)
What are these highlighted vessels within the vessel structure?
Vasa vasorum; vessels that supply outer walls of large vessels. Not pictured: nervi vasorum
Which 2 lumens are here?
Trachea below, elastic artery above. Notice cartilage w/ trachea
Which epithelial cells are distinguishable here?
- Ciliated cells (most of them)
- Mucous cells
- Basal stem cells (small, squished by basement membrane)
Notable layers and structures here
- Pseudostratified tracheal epithelium
- Thick tracheal basement membrane
- Lighter lamina propria
- Darker submucosa
- Tracheal submucosal glands
How can you determine that this is the trachea?
C-shaped cartilage rings, pseudostratified epithelium
What is this accumulation of cells?
Bronchial Associated Lymphoid Tissue (by the trachea)
Which structure is circled?
Intrapulmonary bronchus
Notice it’s in the lung tissue and has cartilage plates
What is the progression of highlighted structures here?
Terminal bronchiole (only club cells)
Transition to alveolar epithelium
Alveolar duct connecting several alveolar sacs which have several alveoli
What is this highlighted layer?
Visceral pleura (serous membrane, mesothelium + CT)
What are the highlighted cells?
Top to bottom: alveolar macrophage (smooth here bc germ-free mouse), AT2 cell (lamellar bodies w/ surfactant), RBCs in alveolar capillaries (surrounded by AT1 cells and aerocytes)
How do you differentiate between AT1s, aerocytes, and gCap cells?
AT1 nuclei will poke into the alveolar epithelium, endothelial cell epithelia poke into the capillary lumen. Aerocytes line capillaries in thin walls (and some thick), gCaps are in thick wall vessels only
Which lung pathology is depicted here?
Panacinar emphysema (all levels of lung), not centrilobular (only centers of lung lobules near respiratory airways. Alveoli wall collapse leads to much larger spaces within lungs; vs atelectasis = collapse of alveoli
Which lung pathology is depicted here?
Pulmonary fibrosis. Lots of scar tissue fibers invading/eliminating alveolar space, CT overgrowth, macrophage accumulations, lymphocyte infiltration, also much thicker visceral pleura serosal layer
