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Semester 4: Haematology > lab investigation of fbc > Flashcards

lab investigation of fbc Flashcards

1
Q

what is haematopoeisis

A

blood cell production, normally occurring in the bone marrow

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2
Q

what is FBC

A

full blood count

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3
Q

Hb

A

Concentration of Hb

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4
Q

Ht

A

Percentage of blood volume that is RBC

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5
Q

MCV (mean cell volume)

A

Average size of the RBC

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6
Q

MCH

A

Average Hb content of the RBC

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7
Q

RDW

A

Range of deviation around the RBC size

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8
Q

Reticulocyte count

A

Reticulocytes are immature red blood cells (RBCs)

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9
Q

what other results are taken from FBC?

A
  • Total WBC
  • Neutrophils
  • Lymphocytes
  • Monocytes
  • Basophils
  • Eosinophils
  • Platelet count & size
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10
Q

what can blood films show for RBCs?

A
  • size
  • colour: Hb content
  • Shape
  • Polychromasia- reticulocyte count
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11
Q

what can blood films show for WBCs?

A
  • numbers (too few or too many)
  • normal morphology
  • immature cells
  • abnormal cells
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12
Q

transfusion requests

A

have to be handwritten by law, minimum of 1600 a day

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13
Q

how is white cell distribution measured by size and staining?

A

the plot is based on light refraction & size
peroxidase is stained for (in neutrophils)
- machine turns data into numbers

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14
Q

blood film for patient with iron deficiency anaemia

A
  • some cells with little Hb: area of central pallor is low

- some elliptocytes

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15
Q

blood film for patient with macrocytic anaemia

A
  • some cells oval shaped
  • lots of little fragments
  • some RBCs very large & same shape as lymphocytes
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16
Q

blood film for patient with haemolytic anaemia

A
  • polychromasia: high no of immature blood cells, slightly purple
  • spherocytes: spherical shaped RBCs
17
Q

blood film for patient with sickle cell anaemia

A
  • sickle cells look like boats or bananas

- target cells: red dot in the middle and then white ring and then normal red ring

18
Q

blood film of patient with infiltration with malignant disease

A

tear drop poikilocytosis: abnormally shaped RBCs

19
Q

blood film for patient with neutrophil leucocytosis

A
  • too many red cells
  • too many white cells
  • could be sepsis
20
Q

blood film for patient with acute myeloblastic leukaemia

A

all the white cell count is leukaemia cells

Semester 4: Haematology (5 decks)

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