Lab Final Flashcards
Small pupils
Old, dark eyes, pilocarpine, heroin, allergies, alcoholism
Big Pupils
Young, light eyes, antihistamine, steroid, scopalamide
CN III
- MR-add
- SR-eleve
- IR-dep
- IO-ext
CN IV
- SO-int
CN VI
- LR-Abd
Addies Tonic Pupil
Efferent pathway. Affected eye is big. POOR direct. Near response is slow but prolonged. will dilate with 0.125% pilocarpine. Veriform movement
Addie’s Syndrome
Decreased corneal sensitivity, deep tendon reflex, tonic pupil
Argyll-Robertson
Tectum. Pupil normal or small and irregular. NO direct. GOOD near. Can be unilateral–>bilateral
APD
Afferent. Normal pupil. Pupil dilates with direct.
Horner’s Syndrome
Sympathetic. Anisocornia in dark. Small pupil. POOR direct and near. Hydroxymethamine 1. One eye-post 1. both-pre
CN III palsy
Eye is down and out. No direct or near response. An emergency
Normal exophathalmous readings
12-21. Up to 24 if black
Diff. in exophathalmous
1-2 mm
Pachymetery
Measures the corneal thickness
Normal corneal thickness
550 nm. Must be within 5 of each other. 570 for white.
Thin cornea
Will have decreased pressures. More at risk of glaucoma as abnormally low
IOP and Pachy
Must adjust IOP by 4 mm hg for every 80 micrometers off average
Insurance and cataract
Must be worse then 20/40
PAM
PT. is dilated. On the SLAMP. Dial in ES. NO rxn. Improvement means good candidate. Smallest line is PA.
BAT
Pt. NOT dialted. Habitual rxn. Acuity will get worse with light if have cataracts.
Super pinhole
Pt. is dilated. Habitual RXN. 5 ft. test distance. Vas should improve.
Interferometer
When they get half right this is their PA. No Rxn. Dilated. For amblyopes and dense cataracts
Cataract test where you are NOT dilated
BAT
Cataract test where you do not wear glasses
PAM, interformeter
Cataract test where you wear glasses
pinhole and bat
+ sidel sign
If you put fluoroscene on and it leaks out. The cornea has ruptured
Loupe and magnet
Superficial FBs
Spud
Mini golf club. Good for embedded FBs
Polytome
swiss army knife
Needle
Sterile cheap
Alger brush
Use to clear up metabolic FB. Leave rust deeper than bowman’s.
Line 1 of Rxn
Med and amount and form
Line 2 of rxn
How many to disp
Line 3
Instructions for pt.
When to do stromal puncture
Pt. with RCE
Care after FB removal
AB, patch, tell them they loose 1/2 field
Patch rule
Patch never sees sunset twice.
OCT
Ocular Coherence Tomography
AS-OCT useful with…
Keratoconus, corneal degenerations, recurrent micro cysts, corneal scars, cornea transplant, angle closure
5-line raster
Series of scans. 2D image
Cube
Horizontal and vertical. Lower resolution but 3D. Good for macula and ON.
Time domain
Old, low resole, slow
Spectral domain
Exact change in wavelength between lasers, high res, faster
Luminescence
Decay in light
How does fluoroscene work
Light is absorbed by luminescent material that causes the light to lose energy and be re-emmited. Absorbs 490 (blue) and emits 520 (green)
Excitation filter
Transmits 490 nm which is the peak absorption
Barrier filter
Transmits 520 which is the emitted peak
Fluorescein solution
Eliminiated by liver and kidneys for 24 hours. Normally use 5 mL at 10%.
If cannot inject dye
30 mg/kg of oral fluoroscene taken 30-60 min after ingestion
When to avoid angiography
Pregnant women. esp in first trimester
Moderately severe reactions
1%. Urticaria, SOB, vasovagal rxn, skin necrosis
Life threatening cond
.0001%. Anaphylactic shock, seizure, cardio collapse
Predmeds with fluoro.
Can use antihistamine or corticosteroids
Scalp needle vein
Makes sure extravasation of fluorescein doesn’t occur.
Set up for procedures
Maximal dilation (6 mm or more is best), color and red free photos
Transient eye
Eye of interest
Procedure
Establish a venous line. Start time and inject dye rapidly (10 sec). Appear in eyes in 8-12 sec. Take photos every 1.5-2 sec in transient eye for 30 sec. Wait for 3-5 minutes and take more photos.
How long to get to eye
8-12 sec
Choroidal Flush
8-12 sec. Choriocapillaris leaks dye freely. Usually little detail as RPE filtures. Will see dye in cilioretinal artery.
Arterial phase
2s after choroidal. Retinal arteries fill. Fills from lumen out. choroid can get patchy
Arteriovenous phase
retinal arteries, capilaries and veins contain fluoroscene. Early part of phase is lamellar phase when fluoroscene is visualized in larger veins.
Venous phase
30 sec after injection. Fluorescein leaves the arteries and veins have increased fluoroscene. Perifoveal capillary network is best visualized here.
Normal macula color
Macula will by hypo fluorescent (taller more pigment RPE, xanthophyll pigment, absence of retinal capillaries)
Mid phase
Recirculation occurs 2-4 min. after injections. The arteries and veins are roughly equal brightness
Late phase
Gradual elimination of dye from retina and choroid. Staining of the optic disc is normal. Late hyper fluorescence is abnormal. Photos normally taken 7-15 min after injection.
Retinal circulation
Supplies inner 2/3 of retina. Non-fenestrated. Blood-retinal barrier via tight junctions. Autoregulation, perfusion pressure has negligible effect on blood flow
Choroidal circulation
Supplies the outer 1/3 of the retina. Fenestrated, low resistance. Blood retinal barrier via tight junction. No autoregulation
Cause of hypofluorescence
Blockage or vascular filling defect
Is it blockage or vascular filling defect
If size/shape/location is same as funds photo–>blockage.
Pre-retinal Hemmorhage
Pre-retinal hemmorhage cause blockage of all retinal and choroid. Will be same as funds photo.
Intraretinal hemmorhage
bleeding stops at 180. Will be blockage. Will see some vasculature.
Subretinal hemmorhage
Will see retinal vasculature.
CHRPE
Subretinal hypertrophy of the RPE. Blocked chroidal fluorescence and normal retinal fluorscene. Blockage.
Choroidal nevus
Blockage at AV stage. Will see vascu.
Non-filling of an artery
Will eventually see back flow so this is why it is important to see whole picture
Retinal capillary nonperfusion
choroidal fluorescene blocked by opaque retina.
CRAO
Blood flow will not get through here quickly. Will tai 30 sec to 1 min instead of 8-12 sec.
Preinjection fluorescence
Autofluorescence or pseduofluorescence
Autofluorescence
Occurs with optic disc drusen and astrocytic hamartomas
Psuedofluorescence
When barrier and excitation filters aren’t well matched.
Early hyperfluorescence
Vascular. Retinal or choroidal.
Microanyeursms
Early hyperflur.
Neovascularization
Will have early hyperfluorecence and late leakage.
Window defect
Early hyper. Transmission of hyper is seen in the choroid due to damage of RPE. Size is uniform. Borders are well defined. Can also be due to macula hole.
Choroid subretinal neovascularization
hyper early. Early fine lacy hyperflur in the sub retinal neovascular. Late=leakage.
Leakage
Dye leaks from an intravascular space into an extravascular space. A and size changes with time.
Pooling
Dye fills an anatomical space with a defined border.
Staining
Deposits of dye in tissue. Normal staining (ON and sclera) Pathological (scars)
How long until fluorescein empties from eye
10-15 min
Normal staining
- hyper of disc margins
- fluor of lamina cribs
- fluor of the sclera at the disc margin (sclera crescent)
- fluor of the scleral in lightly pigment fundus
Cystoid macula edema
Will have petaloid appearance late. Can also have diffuse leakage (late picture)
Central serous retinopathy
Choroidal leakage and pooling into sub retinal space. Early phase shows small hyper fluorescent spot. Late phase shows pooling. Will have borders. Can be smoke stack or ink blot
Pigment epithelial detachment
Pooling of luis between bruch and RPE. Early hyper from area of detached RPE. Late phase showing well demarcated hyperfluo. borders. Will get brighter with time!
Drusenoid PED
Between RPE and bruch. Drusen stains more in late angio
Fibrous scar
Most common location is sub retinal. Will pick up stain as angiogram progresses.
Tumors
early hyperfluor and lake leakage
Widefiled FA
Difficult as take picture at different time
OPTOS
See everything happening at once
OCT angiography
Can perform without fluoroscene