LAB FINAL Flashcards
Hypothalamus
serves as the main control center of the endocrine and autonomic nervous system being in charge of regulating vital bodily functions such as body temperature, fluid balance, food intake, sleep awareness, sexual arousal, memory, emotional expression, and control of stress levels
GnHR (gonadotropin-releasing hormone)
TARGET - anterior pituitary gland
FUNCTION - stimulates secretion of FSH and LH
PRH (prolactin releasing hormone)
TARGET - anterior pituitary gland
FUNCTION - stimulates release of prolactin
Anterior Pituitary Gland (Adenohypophysis)
regulates metabolism, growth, sexual maturation, reproduction, blood pressure, breastfeeding, and the immune response
FSH (follicle stimulating hormone)
TARGET - ovaries and testes
FUNCTION - females: promotes development of ovarian follicle and estrogen secretion - males: promotes spermatogenesis
LH (luteinizing hormone)
TARGET - ovaries and testes
FUNCTION - females: promotes maturation of the ovarian follicle and progesterone secretion - males: promotes secretion of testosterone
PRL (prolactin)
TARGET - mammary glands
FUNCTION - stimulates milk production and secretion
Posterior Pituitary Gland (Neurohypophysis)
stores two neurohormones coming from the hypothalamus - NOT an endocrine gland
Oxytocin
TARGET - uterus and mammary glands
FUNCTION - stimulus powerful uterine contractions during birth and milk ejection in lactating mothers
ADH (antidiuretic hormone)
TARGET - kidneys
FUNCTION - water conservation and electrolyte balance by stimulating the kidneys to reabsorb more water, reducing urine output
Adrenal (Suprarenal) Gland - Cortex
outermost region of the gland - responsible for producing hormones that regulate blood pressure, glucose blood levels, and sexual characteristics
Mineralocorticoids - Aldosterone
TARGET - kidneys
FUNCTION - regulates the reabsorption of water altering blood pressure in the body
Gonadocorticoids - Androgens and Estrogen
TARGET - many
FUNCTION - regulates the development of secondary sexual characteristics
Adrenal (Suprarenal) Gland - Medulla
inner region of the gland, responsible for secreting two hormones that initiate and regulate the fight or flight response
Epinephrine (adrenaline)
TARGET - many
FUNCTION - fight or flight in response to stress
Norepinephrine (noradrenaline)
TARGET - many
FUNCTION - fight or flight in response to stress
Female Gonads: Ovaries
paired female gonads located in the true pelvic cavity
Estrogens
TARGET - many
FUNCTION - growth and development of the female reproductive system and secondary sexual characteristics
Progesterone
TARGET - many
FUNCTION - prepares the endometrium for implantation (potential pregnancy)
Male Gonades: Testes
paired male gonads located in the perineal region
Testosterone
TARGET - many
FUNCTION - growth and development of male reproductive system and secondary sexual characteristics
Pineal Gland
secretes melatonin to regulate the sleep-wake cycle (circadian rhythm)
Melatonin
TARGET - many
FUNCTION - regulates sleep-wake cycle, inhibits reproductive functions, and protects against damage by free radicals
Thyroid Gland
regulates metabolism and blood calcium levels
TH - T4 and T3
TARGET - all cells
FUNCTION - regulates metabolism and cellular oxidation
Calcitonin
TARGET - bones
FUNCTION - regulates calcium deposition in bones
Parathyroid Gland
regulation of calcium levels in the bones and blood
PTH (parathyroid hormone)
TARGET - kidneys and bones
FUNCTION - regulates blood calcium levels
Thymus
maturation of T cells - immune response (stimulates production of antibodies)
Thymulin, Thymosins, Thymopoietin
TARGET - thymus
FUNCTION - development of T cells and immune response
Pancreas
regulates metabolism of glucose, proteins, and lipids
Insulin (Beta Cells)
TARGET - many
FUNCTION - transport glucose into cells
Glucagon (Alpha Cells)
TARGET - liver
FUNCTION - release glucose into blood by breaking down glycogen stores
Lymph
composed mainly of water
carries immune response factors and clears out pathogens
Lymphatic Vasculature
- lymphatic capillaries
- lymphatic vessels
- lymphatic trunks
- right lymphatic duct
- thoracic duct
- cisterna chyli
Lymphatic Capillaries
collect interstitial fluid from tissues, forming lymph
Lymphatic Vessels
divided into superficial and deep
receive lymphatic fluid from lymphatic capillaries and drain it into the lymphatic trunks
Lymphatic Trunks
receive lymphatic fluid from the lymphatic vessels in their respective body regions and drain it into lymphatic ducts
Right Lymphatic Duct
not present in everyone
drains lymphatic fluid from the right superior limb and right side of the head and chest into the venous circulation via the right brachiocephalic vein
Thoracic Duct
drains lymphatic fluid from the rest of the body into the venous circulation via the left brachiocephalic vein
Cisterna Chyli
receives lymphatic drainage from the abdominopelvic regions and lower limbs
Primary Lymphatic Organs
formation and development of lymphocytes
1. bone marrow
2. thymus
Bone Marrow
in the epiphysis of long bones, contains stem cells
production of blood cells and storage of fats
Thymus
site of maturation and selection of T-lymphocytes
Secondary Lymphatic Organs
associated with antibody formation, lymphatic proliferation, and antigen presentation
1. spleen
2. lymph nodes
3. pharyngeal tonsils (adenoids)
4. palatine tonsils (tonsils)
5. lingual tonsils
6. vermiform appendix
Spleen
largest of lymphatic connected to bloodstream
site for T-lymphocyte proliferation and maturation, filtering and recycling of damaged red blood cells, and immune surveillance
Lymph Nodes
monitor the lymph coming from lymphatic vessels and phagocytose foreign matter/cell debris and mount the immune response when necessary
Pharyngeal Tonsils (adenoids)
first line of defense against pathogens that enter the body through the nose and mouth
Palatine Tonsils (tonsils)
first line of defense against pathogens that enter the body through the nose and mouth
Lingual Tonsils
first line of defense against pathogens that enter the body through the nose and mouth
Vermiform Appendix
clonal selection, composed of lymphoid tissue, houses commensal bacteria
External Nose
entrance and exit for air for the respiratory system
Nasal Cavity
filters, warms, and moistens incoming air - acts as a resonance chamber for voice production
1. nasal vestibule
2. nasal septum
3. superior, middle, and inferior nasal concha
4. nasal meatus - superior, middle, and inferior
5. posterior nasal apertures
6. hard palate
7. soft palate
8. paranasal sinuses - frontal, maxillary, sphenoidal, ethmoidal air cells
Nasal Vestibule
filters coarse particles from the air
Nasal Septum
decides the nasal cavity into right and left sides
Superior and Middle Nasal Concha
increase the surface area of the mucosa in the cavity, increase air turbulence to help trap particles in the mucus, and warm the incoming air
Inferior Nasal Meatus
helps from the middle and inferior nasal meatuses
Nasal Meatus - Superior, Middle, and Inferior
control airflow direction, humidification, heating, and filtering or the air inhaled through the nose
Posterior Nasal Apertures
provide exit for the air into the nasopharynx
Hard Palate
form the floor of the nasal cavity and roof of the oral cavity
Soft Palate
aids in swallowing and breathing and enables the pronunciation of some consonants
Paranasal Sinuses – Frontal, Maxillary, Sphenoidal, Ethmoidal Air Cells
resonance chambers for speech and warming of incoming air
Pharynx
serves as a muscular passage for air, food, and fluids from the nose and mouth to the lungs and stomach
1. nasopharynx
a. pharyngotympanic tube
2. oropharynx
3. laryngopharynx
Nasopharynx
passage for air from the nasal cavity into the rest of the oropharynx
tonsils provide protection against pathogens
Pharyngotympanic Tube
connects nasopharynx to the middle ear
Oropharynx
passage for air and swallowed foods
tonsils provide protection against pathogens
Laryngopharynx
passage for air and swallowed foods
Larynx
serves as a passage for air, voice production box, and prevents food from passing into the other regions of the lower respiratory tract
1. thyroid cartilage
2. cricoid cartilage
3. arytenoid cartilage
4. corniculate cartilage
5. epiglottis
6. vestibular ligament and fold
7. vocal ligament and fold
8. glottis
9. rima glottidis
10. thyrohyoid ligament
11. cricothyroid ligament
Thyroid Cartilage
forms the framework of the larynx
Cricoid Cartilage
attaches the larynx to the trachea
Arytenoid Cartilage
anchor the vocal folds
Corniculate Cartilage
form part of the posterior wall of the pharynx
Epiglottis
forms lid over the larynx during swallowing and prevents food from entering the trachea
Vestibular Ligament and Fold
protect the vital folds and help close the glottis when swallowing
Vocal Ligament and Fold
vibrate with expired air for sound production
true structures that produce sound as air passes over them
Glottis
vocal apparatus of the larynx
Rima Glottidis
vocal apparatus of the larynx
Thyrohyoid Ligament
facilitates the superior movement of the larynx during swallowing
Cricothyroid Ligament
connects the cricoid and thyroid cartilages preventing them from moving apart from each other
Lower Respiratory System
- trachea
a. cartilaginous tracheal rings - right and left primary bronchi
- secondary bronchi
- tertiary bronchi
- bronchioles
- respiratory bronchioles
- alveolar duct
- alveolar sac
- alveoli
- respiratory membrane
Trachea
transports air in and out of the lungs during breathing and protects the lower respiratory tract by warming and moistening the air
Cartilaginous Tracheal Rings
reinforce the trachea to keep it open and maintain its posterior open surface, allowing the esophagus to expand when swelling a large bolus of food
Right and Left Primary Bronchi
transport air to and from the lungs
Secondary Bronchi
transport air to and from the lungs
Tertiary Bronchi
transport air to and from the lungs
Bronchioles
transport air to and from the lungs
Respiratory Bronchioles
transport air to and from the lungs
Alveolar Duct
transport air to and from the lungs
Alveolar Sac
contains pulmonary alveoli
Alveoli
exchange oxygen and carbon dioxide by rapid diffusion and secrete surfactant to prevent alveoli from collapsing during exhalation
Respiratory Membrane
exchange oxygen and carbon dioxide by rapid diffusion and secrete surfactant to prevent alveoli from collapsing during exhalation
Lungs - Right and Left
aids in inhalation and exhalation processes and drives the exchange of carbon dioxide for oxygen to drive all bodily functions
General Structures and Regions of the Lung
- Hilum
- Apex
- Base
- Costal Surface
Hilum
site through which neurovasculature, lymphatic vessels, and airway passages enter and exit the lung
Apex
region of the lung
Base
region of the lung
Costal Surface
region of the lung
Right Lung
- lobes
a. superior
b. middle
c. inferior - horizontal fissure
- oblique fissure
Horizontal Fissure
deep groove separating the superior and middle lobes
Oblique Fissure
deep grove separating the middle and inferior lobes
Left Lung
- Lobes
a. superior
b. inferior - oblique fissure
- cardiac notch
- linguala
Oblique Fissure
deep groove separating the superior and inferior lobes
Cardiac Notch
concave region on the medial surface to accommodate the heart
Lingula
tone like projection on medial surface of the superior lobe
Pleura
double layered serous membrane that envelops each lung for protection and lubrication
1. parietal pleura
2. visceral pleura
3. pleural cavity
Parietal Pleura
protects the lungs, anchors them to the thoracic cavity and diaphragm to reduce friction during lung movements
Visceral Pleura
protects the lungs, anchors them to the thoracic cavity and diaphragm to reduce friction during lung movements
Pleural Cavity
protects the lungs, anchors them to the thoracic cavity and diaphragm to reduce friction during lung movements
Muscles of Respiration
- diaphragm
- external intercostals
- internal intercostals
- sternocleidomastoid
- scalenes
- pectoralis minor
- serratus anterior
- external oblique
- internal oblique
- rectus abdominis
Diaphragm
NERVE - phrenic nerve
CONTRACTION - inhalation
RELAXATION - passive exhalation
External Intercostals
NERVE - intercostal nerves
CONTRACTION - inhalation
RELAXATION - passive exhalation
Internal Intercostals
NERVE - intercostal nerves
CONTRACTION - assists relaxed diaphragm and external intercostals during forced exhalation
Sternocleidomastoid
NERVE - spinal accessory nerve (CN XI)
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
Scalenes
NERVE - anterior rami of cervical spinal nerves
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
Pectoralis Minor
NERVE - medial and lateral pectoral nerves
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
Serratus Anterior
NERVE - long thoracic nerve
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
External Oblique
NERVE - anterior rami of thoracic and lumbar spinal nerves
CONTRACTION - assist relaxed diaphragm and external intercostals during forced exhalation
Internal Oblique
NERVE - anterior rami of thoracic and lumbar spinal nerves
CONTRACTION - assist relaxed diaphragm and external intercostals during forced exhalation
Rectus Abdominis
NERVE - anterior rami of thoracic and lumbar spinal nerves
CONTRACTION - assist relaxed diaphragm and external intercostals during forced exhalation
COPD (Chronic Obstructive Pulmonary Disease)
a group of lung diseases that block airflow and make it difficult to breathe
PCOS (polycystic ovarian syndrome)
hormonal disorder causing enlarged ovaries with small cysts on the outer edges
Oral Cavity
- labia (lips)
- labial frenulum
- oral vestibule
- cheeks
- oral cavity
- hard palate
- soft palate
a. uvula - palatoglossal arch
- tongue
- lingual frenulum
Labia (Lips)
open and close the anterior opening of the oral cavity
formed by orbicularis oris muscle covered by skin externally and mucosa internally
Labial Frenulum
connects the inner lip to the gums
Oral Vestibule
receives salivary secretions from the parotid glands and distributes it to the oral cavity proper
Cheeks
form the lateral walls of the oral cavity
muscles of facial expression and mastication
Oral Cavity
entrance to the digestive tract and initiation of digestion by forming the alimentary bolus and moving into the oropharynx
Hard Palate
forms the roof of the oral cavity
Soft Palate
aids in taste, swallowing, breathing, and speech
Uvula
helps close the nasal and pharyngeal passages
Palatoglossal Arch
connects the tongue to the soft palate
Palatopharyngeal Arch
connects the soft palate to the oropharynx
Tongue
forms the floor of the oral cavity
aids in different important processes such as mastication, speech, and taste
Lingual Frenulum
secures the inferior surface of the tongue to the floor of the mouth, stabilizing it during swallowing and speech
Pharynx
two layers of skeletal muscle lined with mucosa that propel food inferiorly into the esophagus
1. oropharynx
2. laryngopharynx
Esophagus
serves as a food and fluid passageway into the stomach without any digestive or absorptive functions
1. lower esophageal sphincter
Lower Esophageal Sphincter
protects the esophagus from highly acidic reflux of gastric contents
Stomach
site for temporary storage and mechanical/chemical digestion of food, transforming the food bolus into chyme
1. cardia
2. fundus
3. body
4. pylorus
a. pyloric orifice
b. pyloric sphincter
5. lesser curvature of the stomach
6. greater curvature of the stomach
7. gastric rugae (folds)
Cardia
inflow region of the stomach
Fundus
dome-shaped dilation of the stomach
Body
largest region of the stomach
Pylorus
funnel-shaped outflow region of the stomach connection to the duodenum
Pyloric Orifice
regulates the passage of gastric contents into the duodenum
thickening of smooth muscle
Pyloric Sphincter
regulates the rate of gastric emptying into the duodenum
ring of smooth muscle
Lesser Curvature of the Stomach
point of attachment for the lesser momentum connecting the stomach to the liver
Greater Curvature of the Stomach
point of attachment for the greater omentum
Gastric Rugae (Folds)
increases the surface area of mucosa in the stomach and secretes acids and enzymes
Small Intestine
- duodenum
- jejunum
- ileum
- circular folds (plicae circulares)
- ileocecal valve
Duodenum
initial portion of SI - extends from pyloric sphincter for about 10 inches, curving around the head of the pancreas
site where most of the digestive absorption of nutrients and water occurs in the gastrointestinal tract
Jejunum
middle portion of SI – continuous with the duodenum and ileum
site where most of the digestive absorption of nutrients and water occurs in the gastrointestinal tract
Ileum
terminal portion of the SI
site where most of the digestive absorption of nutrients and water occurs in the gastrointestinal tract
Circular Folds (Plicae Circulares)
deep transverse folds in SI
force chyme to spiral and slow down as it passes through the small intestine, increasing absorption of nutrients
Ileocecal Valve
sphincter created by the protrusion of smooth muscle of the ileum into the lumen of the cecum
controls the passage of contents from the ileum to the cecum
Large Intestine
responsible for absorption of electrolytes and water, formation, temporary storage, and elimination of feces, and housing the gut microflora
1. cecum
a. vermiform appendix
2. ascending colon
3. right colic (hepatic) flexure
4. transverse colon
5. left colic (splenic) flexure
6. descending colon
7. sigmoid colon
8. rectum
9. anal canal
10. internal anal sphincter
11. external anal sphincter
12. anus
13. teniae coli
14. haustra
15. epiploic (omental) appendages
Cecum
first portion of LI
site for temporary storage of intestinal contents and fluid and electrolyte reabsorption
Ascending Colon
fluid and electrolyte reabsorption, formation of fecal matter
Right Colic (Hepatic) Flexure
fluid and electrolyte reabsorption, formation of fecal matter
Transverse Colon
fluid and electrolyte reabsorption, formation of fecal matter
Left Colic (Splenic) Flexure
fluid and electrolyte reabsorption, formation of fecal matter
Descending Colon
fluid and electrolyte reabsorption, formation of fecal matter
Sigmoid Colon
fluid and electrolyte reabsorption, formation of fecal matter
Rectum
temporary storage of fecal matter and defecation
Anal Canal
temporary storage of fecal matter and defecation
Internal Anal Sphincter
thickening of smooth muscle
temporary storage of fecal matter and defecation
External Anal Sphincter
skeletal muscle
temporary storage of fecal matter and defecation
Anus
temporary storage of fecal matter and defecation
Teniae Coli
3 longitudinal muscle bands of the muscular external layer of the large intestine
Haustra
small pocket-like sacs created by the tensions caused by the teniae coli bands
Epiploic (Omental) Appendages
fat-filled pouches of visceral peritoneum hanging from the surface of the large intestine sometimes absent from the cecum and rectum
Peritoneum
serous membrane lining the walls of the abdominopelvic cavity and the organs within
1. visceral peritoneum
2. parietal peritoneum
3. peritoneal cavity
Visceral Peritoneum
direct contact with abdominopelvic organs
protects abdominopelvic organs and reduces friction while organs move
Parietal Peritoneum
lining the inner wall of the abdominopelvic cavity
protects abdominopelvic organs and reduces friction while organs move
Peritoneal Cavity
space between layers filled with serous peritoneal fluid
protects abdominopelvic organs and reduces friction while organs move
Peritoneal Membrans
formed by multiple layers/folds of parietal peritoneum
1. greater omentum
2. lesser omentum
3. mesentery
a. mesentery proper
b. mesoappendix
c. transverse mesocolon
d. sigmoid mesocolon
Greater Omentum
from greater curvature of the stomach and first portion of the peritoneum hanging over the transverse colon, jejunum, and ileum
prevents parietal and visceral peritoneal layers from adhering to each other
Lesser Omentum
from the lesser curvature of the stomach and first part of the duodenum to the liver - divided into the hepatoduodenal and hepatogastric ligaments
separates the greater sac from the lesser sac of the peritoneal cavity
Mesentery
anchors organs from the posterior abdominal wall and carries neurovasculature to them
Mesentery Proper
anchors the small intestine to the posterior abdominal wall
Mesoappendix
anchors the vermiform appendix to the posterior abdominal wall
Transverse Mesocolon
anchors the transverse colon to the posterior abdominal wall
Sigmoid Mesocolon
anchors the sigmoid colon to the posterior abdominal wall
Divisions of the Peritoneal Cavity
- lesser sac (omental bursa)
- greater sac
- epiploic (omental) forament (forament of Winslow)
Lesser Sac (Omental Bursa)
provides space for movement of the stomach
Greater Sac
space from diaphragm to the pelvic cavity
Epiploic (Omental) Foramen
communicates the lesser and greater sacs
Retroperitoneal Organs
- pancreas
- kindeys
- adrenal glands
- spleen
- descending abdominal aorta
- descending and ascending colon
- ureters
Intraperitoneal Organs
- esophagus
- stomach
- liver
- duodenum
- jejunum
- ileum
- cecum
- vermiform appendix
- transverse colon
- sigmoid colon
- rectum
- inferior mesenteric vein
Teeth Classification
- incisors
- canines
- premolars
- molars
Incisors
shearing/biting
Canines
tearing
Premolars
grinding
Molars
grinding
Teeth Anatomy
- crown
- neck
- root
- periodontal ligament
- dentin
- pulp cavity
- root canal
Crown
superior part of the tooth above the gingiva
covered by enamel
Neck
region between the crown and root
covered by cement
Root
inferior region of the tooth deep to the gingiva embedded in the bones
covered by cement
Periodontal Ligament
small ligament surrounding the root of teeth
provides attachment to the tooth socket and cushioning
Dentin
material composing the build of the tooth deep into the enamel and cement layers surrounding the pulp cavity
Pulp Cavity
space deep in the crown and neck of the tooth filled with pulp and blood vessels and nerves
pulp forms and provides nutrients to the dentin
Root Canal
distal extension of the pulp cavity inside the neck and root of the tooth
passage containing blood vessels and nerves entering and leaving a tooth
Salivary Glands
- parotid glands
- submandibular glands
- sublingual glands
Parotid Glands
secretes saliva to start the chemical digestions or food in the oral cavity, forming and lubricating the bolus
Submandibular Glands
secretes saliva to start the chemical digestions or food in the oral cavity, forming and lubricating the bolus
Sublingual Glands
secretes saliva to start the chemical digestions or food in the oral cavity, forming and lubricating the bolus
Liver
produces bile that emulsifies fats, breaking them into small droplets to help their absorption - stores glycogen and fat-soluble vitamins, detoxifies the blood, and synthesizes proteins
1. lobes
2. falciform ligament
3. round ligament of the liver
4. porta hepatis
5. hepatocytes
6. portal triad
Lobes
right, left, caudate, quadrate
Falciform Ligament
peritoneal reflection
attaches the liver to the diaphragm and anterior abdominal wall
Round Ligament of the Liver
located on free edge of the falciform ligament, extending from the umbilicus to the liver
fibrous remnant of the umbilical vein
Porta Hepatis
entry and exit point for lymphatics, blood vessels, and nerves of the liver
Hepatocytes
secrete bile, gluconeogenesis (converting amino acids into glucose), breakdown of ingested toxins, and storage of lipids, glycogen, and iron
Portal Triad
arrangement of the following three basic structures at the end of the liver lobules: a portal arteriole, portal venule, and bile duct
Gallbladder and Biliary System
- bile canaliculi
- bile ducts
- right and left hepatic ducts
- common hepatic duct
- cystic duct
- gallbladder
- common bile duct
Bile Canaliculi
carry bile from hepatocytes to bile ducts inside the liver
Bile Ducts
receive bile from bile canaliculi and carry it into the right and left hepatic ducts
Right and Left Hepatic Ducts
receive bile from bile ducts in the liver and carry them to the common bile duct
Common Hepatic Duct
receives bile from right and left hepatic ducts and carries it into the common bile duct when we have ingested food or to the cystic duct when we are fasting
Cystic Duct
transports bile to the gallbladder for storage or out of the gallbladder when needed
Gallbladder
stores bile produced in the liver during periods of fasting
Common Bile Duct
transports bile from the liver/gallbladder into the duodenum
Pancreas
secretes enzymes that aid in digestion, hormones that regulate glucose plasma levels (Insulin and glucagon)
1. head
2. uncinate process
3. neck
4. body
5. tail
6. main pancreatic duct
7. hepatopancreatic duct
8. hepatopancreatic sphincter
9. major duodenal papilla
10. accessory pancreatic duct
11. minor duodenal papilla
Head
broad medial aspect of the pancreas next to the duodenum
Uncinate Process
projection of the head of the pancreas extending posteriorly to the superior mesenteric artery and vein
Neck
short region connecting the head to the body anterior to the superior mesenteric artery and vein
Body
region between the neck and the tail
Tail
most lateral region of the pancreas
Main Pancreatic Duct
transport and deliver digestion enzymes to the duodenum
Hepatopancreatic Duct (Ampulla of Vater)
transport and deliver digestion enzymes to the duodenum in addition to bile
Hepatopancreatic Sphincter (Sphincter of Odd)
controls the release of bile and enzymes at the Ampulla of Vater and prevents reflux of duodenal contents into it
Major Duodenal Papilla
release of pancreatic enzymes and bile into the duodenum
Accessory Pancreatic Duct
releases pancreatic enzymes into the duodenum
Minor Duodenal Papilla
release of pancreatic enzymes into the duodenum
Embryological Divisions of the Digestive System
- foregut
- midgut
- hindgut
Foregut
pharynx, esophagus, stomach, pancreas, liver, biliary system, and the first segment of the duodenum
Midgut
distal half of the duodenum, jejunum, ileum, cecum, vermiform appendix, ascending colon, and proximal 2/3 of transverse colon
Hindgut
distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, superior 2/3 of the anal canal
External Anatomy of the Kidney
- hilum
- parietal peritoneum
- renal fascia
- perirenal fat
- pararenal fat
- fibrous capsule
Hilum
point of entry/exit for ureters, renal blood vessels, and nerves
Parietal Peritoneum
provide protection and anchoring to the kidney
Renal Fascia
provide protection and anchoring to the kidney
Perirenal Fat
provide protection and anchoring to the kidney
Pararenal Fat
provide protection and anchoring to the kidney
Fibrous Capsule
makes the kidneys adaptable to the constant pressure changes within it
Internal Anatomy of the Kidney
- renal cortex
a. renal columns - renal medulla
- renal pyramid
- renal papilla
- renal lobe
Renal Cortex
receives 95% of the blood supply of the kidney and contains renal corpuscles, proximal convoluted tubules, and peritublar capillaries
Renal Columns
separate adjacent pyramids and transport blood vessels between the renal cortex and the renal medulla
Renal Medulla
receive 5% of the kidney’s blood supply
contain the nephron loops, vasa recta, and collecting ducts. help maintain the salt/water balance and concentrate urine
Renal Pyramid
receive 5% of the kidney’s blood supply
contain the nephron loops, vasa recta, and collecting ducts. help maintain the salt/water balance and concentrate urine
Renal Papilla
contains terminal distal ends of collecting ducts that drain urine into the minor calyces
Renal Lobe
region consisting of a renal pyramid plus the overlying renal cortex and its adjacent renal columns
Chamber System of the Kidneys
- minor calyx
- major calyx
- renal pelvis
- renal sinus
Minor Calyx
transports bring from the collecting acts of the renal papilla to a major calyx
Major Calyx
transports urine from several minor calyces to the renal pelvis
Renal Pelvis
transports bring from the major calyces to a ureter
Renal Sinus
region containing the minor and major calyces and the renal pelvis
Blood Supply to the Kidneys
- renal artery
- segmental arteries
- interlobar arteries
- arcuate arteries
- cortical radiate arteries
- afferent arteriole
- glomerulus
- efferent arteriole
- vasa recta
- peritubular capillaries
- cortical radiate, arcuate, interlobar, segmental, and renal veins
Renal Artery
carry oxygenated blood to the kidneys for its own supply and to also be filtered and remove metabolic waste and excess water and absorb nutrients and minerals
Segmental Arteries
carry oxygenated blood to the kidneys for its own supply and to also be filtered and remove metabolic waste and excess water and absorb nutrients and minerals
Interlobar Arteries
carry oxygenated blood to the kidneys for its own supply and to also be filtered and remove metabolic waste and excess water and absorb nutrients and minerals
Arcuate Arteries
carry oxygenated blood to the kidneys for its own supply and to also be filtered and remove metabolic waste and excess water and absorb nutrients and minerals
Cortical Radiate Arteries
carry oxygenated blood to the kidneys for its own supply and to also be filtered and remove metabolic waste and excess water and absorb nutrients and minerals
Afferent Arteriole
supply blood to individual nephrons for filtration in the glomerulus
Glomerulus
blood filtration
Efferent Arteriole
drains glomerulus into the cortical radiate veins and form the vasa recta or peritubular capillaries
Vasa Recta
supply juxtaglomerular nephrons collecting and transporting water and solutes within the renal medulla
Peritubular Capillaries
supply cortical nephrons to collect water and solutes reabsorbed by the nephron and deliver other solutes to the nephron for secretion
Cortical Radiate, Arcuate, Interlobar, Segmental, and Renal Veins
drain kidney, take deoxygenated blood into the inferior vena cava back to the heart
Microscopic Anatomy of the Kidneys
- nephron
a. cortical nephron
b. juxtamedullary nephron
Nephron
functional unit of the kidneys that produce urine from filtrating blood
Cortical Nephron
most numerous nephrons, located almost entirely within the renal cortex
Juxtamedullary Nephron
small percentage of the total number of nephrons
have their renal corpuscle located close to the corticomedullary junctions and have long nephron loops extending deep into the renal medulla
Renal Corpuscle
- glomerular capsule
- glomerular capsule space
- glomerulus
Glomerular Capsule
nephron’s filtration apparatus
Glomerular Capsule Space
nephron’s filtration apparatus
Glomerulus
nephron’s filtration apparatus
Renal Tubular System
- proximal convoluted tubule
- nephron loop - ascending and descending limbs
- distal convoluted tubule
Proximal Convoluted Tubule
reabsorbs ~65% of of the filtrate coming from the renal corpuscle and specializes in ion reabsorption, passing them into the peritubular capillaries
Nephron Loop - Ascending and Descending Limbs
specializes in water reabsorption from the tubular fluid (descending limb) and NaCl (ascending limb)
Dital Convoluted Tubule
further ion reabsorption and secretion from tubular fluid
Collecting System
- collecting duct
- papillary duct
Collecting Duct
reabsorbs excess water from tubular fluid in the renal medulla
Papillary Duct
collect tubular fluid from multiple collecting ducts and delivers it to a minor calyx
Ureter
transports bring from the kidneys to the urinary bladder
Urinary Bladder
- detrusor muscle
- body
- fundus
- apex
- neck
- trigone
a. ureteric orifice
Detrusor Muscle
relaxation of this muscle allows for filling of the bladder with urine, contraction of this muscle helps with excretion of urine
Trigone
“funnel” that channels using into the urethra when the urinary bladder contracts
Ureteric Orifice
empties the ring from the ureters into the urinary bladder
Urethra
- internal urethral sphincter
- internal urethral orifice
- external urethral sphincter
- external urethral orifice
Internal Urethral Sphincter
provides involuntary control over the exertion of urine from the urinary bladder
Internal Urethral Orifice
emptying of the urinary bladder into the urethra
External Urethral Sphincter
provides voluntary control of the excretion of urine
External Urethral Orifice
excretion of urine
External Female Genitalia - Vulva
- mons pubis
- labia majora
- labia minora
- vestibule
- clitoris
a. prepuce of clitoris
b. glans of clitoris
c. body of clitoris
d. crus of clitoris - bulb of the vestibule
- greater vestibular gland
- hymen
Mons Pubis
covers and protects the pubic symphysis
Labia Majora
protect the vaginal and external urethral orifices
Labia Minora
protect the vaginal and external urethra orifices and enclose the vestibule
Vestibule
contains the clitoris, and the external urethral and the vaginal orifices
Clitoris
mass of erectile tissue at the anterior convergence of the labia minora
sexual pleasure
Prepuce of Clitoris
skin fold formed by the union of the labia minora surrounding the body of the clitoris
sexual pleasure
Glans of Clitoris
“head of the clitoris”
small protrusion at the end of the body of the clitoris
sexual pleasure
Body of Clitoris
region formed by the union of crura from both sides at the midline on the anterior end of the vestibule
sexual pleasure
Crus of the Clitoris
attached to ischiopubic ramus, covered by the ischiocavermosus muscles, convergences forms the body
sexual pleasure
Bulb of the Vestibule
deep to labia minora and lateral to the vestibule, covered by the bulbospongiosus muscle
sexual pleasure
Greater Vestibular Gland
secretes mucus to lubricate the vagina
Hymen
partially covers the vaginal orifice to potentially protect the vagina from bacteria and foreign objects entering the vagina
Internal Female Genitalia
reproductive organs located inside the pelvic cavity
1. ovary
2. fallopian tube
a. infundibulum with fimbrae
b. ampulla
c. isthmus of the uterine tube
d. intramural part
3. uterus
4. vagina
a. vaginal orifice
b. vaginal fornix - anterior, posterior, and lateral
Ovary
site for maturation and release of the ovum and serves as an endocrine gland that releases estrogen and progesterone
Fallopian/Uterine Tube
transport of the ovum from the ovary to the uterus, the usual site for ovum fertilization
Infundibulum with Fimbriae
distal part of tube that opens in the peritoneal cavity
transport of the ovum from the ovary to the uterus, the usual site for ovum fertilization
Ampulla
longest and widest portion of the uterine tube, most common site of fertilization
transport of the ovum from the ovary to the uterus, the usual site for ovum fertilization
Isthmus of the Uterine Tube
narrowest portion of the tube, medial to the ampulla
transport of the ovum from the ovary to the uterus, the usual site for ovum fertilization
Intramural/Uterine Part
portion within the uterine wall, opens into the uterine cavity
transport of the ovum from the ovary to the uterus, the usual site for ovum fertilization
Uterus
during the menstrual cycle, the inner lining (endometrium) proliferates, preparing for embryo implantation but if implantation doesn’t occur it sloughs off
when implantation of a fertilized egg occurs, it serves as a place for the growing embryo and placenta
Vagina
facilitates menstruation, sexual intercourse, and childbirth
Vaginal Orifice
opening at the distal end of the vagina in the vestibule
facilitates menstruation, sexual intercourse, and childbirth
Vaginal Fornix - Anterior, Posterior, and Lateral
reservoir for semen after intravaginal ejaculation
Uterine Wall
- endometrium
- myometrium
- perimetrium
Endometrium
thick mucosal lining with a functional and basal layer
provides optimal conditions for the implantation of an embryo, helps maintain pregnancy if it occurs, and menstruation if pregnancy doesn’t occur
Myometrium
thick smooth muscle layer, superficial to the endometrium
gives the structural integrity to the uterus, expands during pregnancy to sustain a growing fetus and it contracts during labor to help parturition
Perimetrium
outer serosal layer, superficial to the myometrium
secretes fluid to reduce the friction of the uterus within the pelvic cavity
Regions of the Uterus
- fundus
- body
- uterine cavity
- cervix
a. internal os
b. external os
c. cervical canal
Fundus
base of the body located superiorly
Body
main region uterus connected to the uterine tubes
Uterine Cavity
internal chamber
allows the passage of sperm into the uterine tube where fertilization of the ovum may take place
Cervix
distal neck
connects the body of the uterus to the vagina and facilitates the passage of sperm into the uterine cavity
prevents bacterial infection in the vagina from reaching the uterus
Internal Os
communication between the uterine cavity and the vagina
External Os
communication between the uterine cavity and the vagina
Cervical Canal
passageway between the internal and eternal os
communication between the uterine cavity and the vagina
Ligaments and Peritoneal Folds of the Uterus and Ovaries
- broad ligament of the uterus
a. mesovarium
b. mesoalpinx
c. mesometrium - suspensory ligament of the ovaries
- round ligament of the uterus
- ovarian ligament
Broad Ligament of the Uterus
maintain the uterus and ovaries in position and carry blood vessels, lymphatics, and nerves to and from them
Mesovarium
covers the ovarian ligaments
maintain the uterus and ovaries in position and carry blood vessels, lymphatics, and nerves to and from them
Mesosalpinx
covers the uterine/fallopian tube
maintain the uterus and ovaries in position and carry blood vessels, lymphatics, and nerves to and from them
Mesometrium
extends from the ovarian ligament to the pelvic floor and body of the uterus
maintain the uterus and ovaries in position and carry blood vessels, lymphatics, and nerves to and from them
Suspensory Ligament of the Ovaries
attaches to the lateral abdominal wall extending from the abdominal aorta to the ovaries
maintain the uterus and ovaries in position and carry blood vessels, lymphatics, and nerves to and from them
Round Ligament of the Uterus
extends from the proximal region of the uterus to the connective tissue of the labia majora after passing through the inguinal canal
contains lymphatic draining the uterine region into the femoral and into the superficial lymph nodes
Ovarian Ligament
extension of round ligament extending from the ovaries to the uterus
anchors the ovaries to the uterus
Spaces Created by the Peritoneum
- Rectouterine Pouch
- Vesicouterine Pouch
Rectouterine Pouch
reduces the friction between the rectum and uterus as there are constant changes in their volume
Vesicouterine Pouch
prevents the urinary bladder from attaching to the uterus
Female Breast
- mammary glands
- lactiferous ducts
- areola
- nipple
Mammary Glands
produce milk under the influence of prolactin and eject milk under the influence of oxytocin
Lactiferous Ducts
transport milk from the mammary glands to the nipple
Areola
secrete lubrication oil to protect the nipple
Nipple
secretion of milk
Male External and Internal Genitalia
- scrotum
a. dartos muscle
b. cremaster muscle - testis
- tunica vaginalis testis - parietal and visceral layers
- tunica albuginea
- seminiferous tubules
- rete testis
- epididymis
- spermatic cord
a. ductus deferens
b. ampulla of the ductus deferens
c. pampiniform plexus
d. testicular artery - seminal gland
- ejaculatory duct
- prostate gland
- bulbourethral gland
- penis
a. bulb of the penis
b. body of the penis
c. glans of the penis - corpus spongiosum
- corpus cavernosum
- spongy urethra
Scotum
contains the testis and lower parts of the spermatic cord, allows the testes to be positioned outside of the body for optimal temperature needed for sperm development
Dartos Muscle
contraction gives the scrotum its wrinkled appearance by regulating its surface area
Cremaster Muscle
contraction pulls testes closer to the abdominopelvic cavity when outside temperature is low
Testis
produces sperm and testosterone
Tunica Vaginalis Tetis - Parietal and Visceral Layers
secretes serous fluid to allow for reduced friction of the testis inside the scrotum
Tunica Albuginea
covers and protects each testis
Seminiferous Tubules
production site of sperm
Rete Testis
transports immature sperm from seminiferous tubules to the epididymis
Epididymis
storage and maturation of spermatozoa
Spermatic Cord
encloses ductus deferens, testicular blood vessels and nerves
Ductus Deferens
transports sperm from the epididymis to ampulla
Ampulla of the Ductus Deferens
empties sperm into the ejaculatory duct
Pampiniform Plexus
drains venous blood from the testes and spermatic cord
Testicular Artery
supplies oxygenated blood to the testes and spermatic cord
Seminal Gland
secretes yellowish alkaline viscous fluid that constitutes about 70-85% of semen. It contains fructose and citric acid to nourish that sperm and prostaglandins to enhance sperm motility
Ejaculatory Duct
receives seminal fluid from seminal vesicles and sperm from the ductus deferens
contraction of this duct propels sperm through the prostate gland
Postate Gland
secretes an acidic, milky fluid into the urethra
Bulbourethral Gland
clear alkaline mucus that lubricates the tip of the penis and neutralizes traces of acidic urine remaining in the male urethra prior to ejaculation
Penis
provides outlet for urine and seminal fluid
Bulb of the Penis
attaches the penis to the perineum and contains the bulb of the penis and crura
Body of the Penis
contains erectile tissues and spongy urethra
Glans of the Penis
contains the external urethral orifice
Corpus Spongiosum
helps the penis get into an erect state, keeping the spongy urethra open which is necessary for ejaculation
Corpus Cavernosum
helps penis get into an erected state
Spongy Urethra
delivers urine and seminal fluid outside of the male penis
Male Urethra
- prostatic urethra
- membranous urethra
- spongy urethra
Prostatic Urethra
transport semen from the ejaculatory duct to the outside
Membranous Urethra
transport semen from the ejaculatory duct to the outside
Urogenital Triangle - Superficial Layer
- ischiocavernosus
- bulbospongiosus
- superficial transverse perineal muscle
Ischiocavernosus
O - ischial tuberosity
I - erectile tissue of penis or clitoris
A - erection of penis or clitoris
N - pudendal nerve
Bulbospongiosus
O - central tendon of perineum
I - erectile tissue of penis or clitoris
A - erection of penis or clitoris
N - pudendal nerve
Superficial Transverse Perineal Muscle
O - ischial tuberosity
I - perineal body
A - stablizes the perineal body
N - pudendal nerve
Urogenital Triangle - Deep Layer
- deep transverse perineal muscle
- external urethral sphincter
Deep Transverse Perineal Muscle
O - ischial ramus
I - perineal body
A - supports pelvic organs
N - pudendal nerve
External Urethral Sphincter
O - ischiopubic ramus
I - midline raphe
A - constricts urehtra to allow for the voluntary control of urination
N - pudendal nerve
Anal Triangle
external anal sphincter
External Anal Sphincter
O - skin and fascia surrounding the anus
I - perineal body
A - constricts the anus to allow for the voluntary control of defecation
N - pudendal nerve
Muscles of the Pelvic Floor - Pelvic Diaphragm
- levator ani
- coccygeus
Levator Ani
O - pubis and spine of the ischium
I - coccyx and levator ani from the opposite side
A - support the pelvic organs, preventing them from prolapsing
N - pudendal nerve
Coccygeus
O - spine of ischium
I - sacrum and coccyx
A - supports the pelvic organs, preventing them from prolapsing
N - sacral spinal nerves
Muscles of the Lateral Wall of the Pelvis
- obturator internus
- piriformis
Obturator Internus
O - obturator membrane and obturator foramen bony boundaries
I - greater trochanter of the femur
A - form the lateral wall of the pelvis
N - nerve to obturator internus
Piriformis
O - sacrum
I - greater trochanter of the femur
A - form the lateral wall of the pelvis
N - nerve to the piriformis
Internal Iliac Artery
supplies the walls and viscera of the pelvis, perineum, and gluteal region
1. umbilical artery
2. superior vesical artery
3. inferior vesical artery
4. obturator artery
5. pudendal artery
6. inferior gluteal artery
7. superior gluteal artery
Umbilical Artery
major blood vessel for fetal circulation
after birth, it supplies oxygenated blood to the urinary bladder
Superior Vesical Artery
supply oxygenated blood to the superior surface of the urinary bladder
Interior Vesical Artery
supply oxygenated blood to the posteroinferior surface of the urinary bladder
Obturator Artery
supplies the adductor compartment of the thigh muscles
Pudendal Artery
supplies oxygenated blood to the urogenital and anal triangles
Inferior Gluteal Artery
supplies the sciatic nerve, gluteus maximus, rotator hip muscles, and levator ani muscles plus the skin of the gluteal and thigh regions
Superior Gluteal Artery
supply gluteal muscles and rotator hip muscles plus the skin over the sacrum
Fertilization
sperm penetration of the ovum
1. zygote
Zygote
fertilized ovum - single cell with fertilization membrane surrounding it
Cleavage
rapid mitotic divisions of the zygote to form an embryo
1. 4-cell stage
2. morula
3. blastocyst
a. inner cell mass
b. trophoblast
4-Cell Stage
cluster of divided cells being made from a zygote undergoing mitotic divisions
Morula
solid mass of cells when the blastocyst has divided by the 32nd time, around the 3rd day after fertilization
Blastocyst
last stage of cleavage when there is the appearance of a central cavity within the solid mass of cells (morula)
Inner Cell Mass (Embryoblast)
inner mass of cells surrounded by the trophoblast
forms the embryo’s body
Trophoblast
outer single flattened cell layer
encloses the embryoblast, secretes enzymes to help during implantation and it becomes the chorion (precursor to the placenta after implantation)
Gastrulation
formation of primary germ layers in the embryo
1. early-stage gastrula
2. later stage gastrula
Early-Stage Gastrula
two-layer embryo
precursor to three-layer embryo
Later State Gastrula
three-layer embryo, primary germ layers
precursor to all tissues in the human body
Primary Germ Layers
- ectoderm
- mesoderm
- endoderm
Ectoderm
outermost layer
1. epidermis and accessory skin structures
2. organs of special senses
3. glands such as the pituitary, pineal, and medulla of the adrenal glands
Mesoderm
middle layer
1. internal reproductive organs
2. most smooth muscle
3. most lymphoid organs and tissues
Endoderm
innermost layer
1. epithelial lining of the respiratory, GI, urinary and reproductive tracts
Fetal Development
embryo becomes a fetus by week 9 after fertilization
1. placenta
2. amniotic sac and fluid
3. umbilical cord
Placenta
meeting point of maternal and fetal circulatory systems
provides oxygen and nutrients to the fetus and removes its waste materials and carbon dioxide
Amniotic Sac and Fluid
cushions and protects the fetus fro mechanical injuries, adhesions, and temperature extremes
Umbilical Cord
vital passage connecting the fetus to the placenta