LAB FINAL Flashcards
Hypothalamus
serves as the main control center of the endocrine and autonomic nervous system being in charge of regulating vital bodily functions such as body temperature, fluid balance, food intake, sleep awareness, sexual arousal, memory, emotional expression, and control of stress levels
GnHR (gonadotropin-releasing hormone)
TARGET - anterior pituitary gland
FUNCTION - stimulates secretion of FSH and LH
PRH (prolactin releasing hormone)
TARGET - anterior pituitary gland
FUNCTION - stimulates release of prolactin
Anterior Pituitary Gland (Adenohypophysis)
regulates metabolism, growth, sexual maturation, reproduction, blood pressure, breastfeeding, and the immune response
FSH (follicle stimulating hormone)
TARGET - ovaries and testes
FUNCTION - females: promotes development of ovarian follicle and estrogen secretion - males: promotes spermatogenesis
LH (luteinizing hormone)
TARGET - ovaries and testes
FUNCTION - females: promotes maturation of the ovarian follicle and progesterone secretion - males: promotes secretion of testosterone
PRL (prolactin)
TARGET - mammary glands
FUNCTION - stimulates milk production and secretion
Posterior Pituitary Gland (Neurohypophysis)
stores two neurohormones coming from the hypothalamus - NOT an endocrine gland
Oxytocin
TARGET - uterus and mammary glands
FUNCTION - stimulus powerful uterine contractions during birth and milk ejection in lactating mothers
ADH (antidiuretic hormone)
TARGET - kidneys
FUNCTION - water conservation and electrolyte balance by stimulating the kidneys to reabsorb more water, reducing urine output
Adrenal (Suprarenal) Gland - Cortex
outermost region of the gland - responsible for producing hormones that regulate blood pressure, glucose blood levels, and sexual characteristics
Mineralocorticoids - Aldosterone
TARGET - kidneys
FUNCTION - regulates the reabsorption of water altering blood pressure in the body
Gonadocorticoids - Androgens and Estrogen
TARGET - many
FUNCTION - regulates the development of secondary sexual characteristics
Adrenal (Suprarenal) Gland - Medulla
inner region of the gland, responsible for secreting two hormones that initiate and regulate the fight or flight response
Epinephrine (adrenaline)
TARGET - many
FUNCTION - fight or flight in response to stress
Norepinephrine (noradrenaline)
TARGET - many
FUNCTION - fight or flight in response to stress
Female Gonads: Ovaries
paired female gonads located in the true pelvic cavity
Estrogens
TARGET - many
FUNCTION - growth and development of the female reproductive system and secondary sexual characteristics
Progesterone
TARGET - many
FUNCTION - prepares the endometrium for implantation (potential pregnancy)
Male Gonades: Testes
paired male gonads located in the perineal region
Testosterone
TARGET - many
FUNCTION - growth and development of male reproductive system and secondary sexual characteristics
Pineal Gland
secretes melatonin to regulate the sleep-wake cycle (circadian rhythm)
Melatonin
TARGET - many
FUNCTION - regulates sleep-wake cycle, inhibits reproductive functions, and protects against damage by free radicals
Thyroid Gland
regulates metabolism and blood calcium levels
TH - T4 and T3
TARGET - all cells
FUNCTION - regulates metabolism and cellular oxidation
Calcitonin
TARGET - bones
FUNCTION - regulates calcium deposition in bones
Parathyroid Gland
regulation of calcium levels in the bones and blood
PTH (parathyroid hormone)
TARGET - kidneys and bones
FUNCTION - regulates blood calcium levels
Thymus
maturation of T cells - immune response (stimulates production of antibodies)
Thymulin, Thymosins, Thymopoietin
TARGET - thymus
FUNCTION - development of T cells and immune response
Pancreas
regulates metabolism of glucose, proteins, and lipids
Insulin (Beta Cells)
TARGET - many
FUNCTION - transport glucose into cells
Glucagon (Alpha Cells)
TARGET - liver
FUNCTION - release glucose into blood by breaking down glycogen stores
Lymph
composed mainly of water
carries immune response factors and clears out pathogens
Lymphatic Vasculature
- lymphatic capillaries
- lymphatic vessels
- lymphatic trunks
- right lymphatic duct
- thoracic duct
- cisterna chyli
Lymphatic Capillaries
collect interstitial fluid from tissues, forming lymph
Lymphatic Vessels
divided into superficial and deep
receive lymphatic fluid from lymphatic capillaries and drain it into the lymphatic trunks
Lymphatic Trunks
receive lymphatic fluid from the lymphatic vessels in their respective body regions and drain it into lymphatic ducts
Right Lymphatic Duct
not present in everyone
drains lymphatic fluid from the right superior limb and right side of the head and chest into the venous circulation via the right brachiocephalic vein
Thoracic Duct
drains lymphatic fluid from the rest of the body into the venous circulation via the left brachiocephalic vein
Cisterna Chyli
receives lymphatic drainage from the abdominopelvic regions and lower limbs
Primary Lymphatic Organs
formation and development of lymphocytes
1. bone marrow
2. thymus
Bone Marrow
in the epiphysis of long bones, contains stem cells
production of blood cells and storage of fats
Thymus
site of maturation and selection of T-lymphocytes
Secondary Lymphatic Organs
associated with antibody formation, lymphatic proliferation, and antigen presentation
1. spleen
2. lymph nodes
3. pharyngeal tonsils (adenoids)
4. palatine tonsils (tonsils)
5. lingual tonsils
6. vermiform appendix
Spleen
largest of lymphatic connected to bloodstream
site for T-lymphocyte proliferation and maturation, filtering and recycling of damaged red blood cells, and immune surveillance
Lymph Nodes
monitor the lymph coming from lymphatic vessels and phagocytose foreign matter/cell debris and mount the immune response when necessary
Pharyngeal Tonsils (adenoids)
first line of defense against pathogens that enter the body through the nose and mouth
Palatine Tonsils (tonsils)
first line of defense against pathogens that enter the body through the nose and mouth
Lingual Tonsils
first line of defense against pathogens that enter the body through the nose and mouth
Vermiform Appendix
clonal selection, composed of lymphoid tissue, houses commensal bacteria
External Nose
entrance and exit for air for the respiratory system
Nasal Cavity
filters, warms, and moistens incoming air - acts as a resonance chamber for voice production
1. nasal vestibule
2. nasal septum
3. superior, middle, and inferior nasal concha
4. nasal meatus - superior, middle, and inferior
5. posterior nasal apertures
6. hard palate
7. soft palate
8. paranasal sinuses - frontal, maxillary, sphenoidal, ethmoidal air cells
Nasal Vestibule
filters coarse particles from the air
Nasal Septum
decides the nasal cavity into right and left sides
Superior and Middle Nasal Concha
increase the surface area of the mucosa in the cavity, increase air turbulence to help trap particles in the mucus, and warm the incoming air
Inferior Nasal Meatus
helps from the middle and inferior nasal meatuses
Nasal Meatus - Superior, Middle, and Inferior
control airflow direction, humidification, heating, and filtering or the air inhaled through the nose
Posterior Nasal Apertures
provide exit for the air into the nasopharynx
Hard Palate
form the floor of the nasal cavity and roof of the oral cavity
Soft Palate
aids in swallowing and breathing and enables the pronunciation of some consonants
Paranasal Sinuses – Frontal, Maxillary, Sphenoidal, Ethmoidal Air Cells
resonance chambers for speech and warming of incoming air
Pharynx
serves as a muscular passage for air, food, and fluids from the nose and mouth to the lungs and stomach
1. nasopharynx
a. pharyngotympanic tube
2. oropharynx
3. laryngopharynx
Nasopharynx
passage for air from the nasal cavity into the rest of the oropharynx
tonsils provide protection against pathogens
Pharyngotympanic Tube
connects nasopharynx to the middle ear
Oropharynx
passage for air and swallowed foods
tonsils provide protection against pathogens
Laryngopharynx
passage for air and swallowed foods
Larynx
serves as a passage for air, voice production box, and prevents food from passing into the other regions of the lower respiratory tract
1. thyroid cartilage
2. cricoid cartilage
3. arytenoid cartilage
4. corniculate cartilage
5. epiglottis
6. vestibular ligament and fold
7. vocal ligament and fold
8. glottis
9. rima glottidis
10. thyrohyoid ligament
11. cricothyroid ligament
Thyroid Cartilage
forms the framework of the larynx
Cricoid Cartilage
attaches the larynx to the trachea
Arytenoid Cartilage
anchor the vocal folds
Corniculate Cartilage
form part of the posterior wall of the pharynx
Epiglottis
forms lid over the larynx during swallowing and prevents food from entering the trachea
Vestibular Ligament and Fold
protect the vital folds and help close the glottis when swallowing
Vocal Ligament and Fold
vibrate with expired air for sound production
true structures that produce sound as air passes over them
Glottis
vocal apparatus of the larynx
Rima Glottidis
vocal apparatus of the larynx
Thyrohyoid Ligament
facilitates the superior movement of the larynx during swallowing
Cricothyroid Ligament
connects the cricoid and thyroid cartilages preventing them from moving apart from each other
Lower Respiratory System
- trachea
a. cartilaginous tracheal rings - right and left primary bronchi
- secondary bronchi
- tertiary bronchi
- bronchioles
- respiratory bronchioles
- alveolar duct
- alveolar sac
- alveoli
- respiratory membrane
Trachea
transports air in and out of the lungs during breathing and protects the lower respiratory tract by warming and moistening the air
Cartilaginous Tracheal Rings
reinforce the trachea to keep it open and maintain its posterior open surface, allowing the esophagus to expand when swelling a large bolus of food
Right and Left Primary Bronchi
transport air to and from the lungs
Secondary Bronchi
transport air to and from the lungs
Tertiary Bronchi
transport air to and from the lungs
Bronchioles
transport air to and from the lungs
Respiratory Bronchioles
transport air to and from the lungs
Alveolar Duct
transport air to and from the lungs
Alveolar Sac
contains pulmonary alveoli
Alveoli
exchange oxygen and carbon dioxide by rapid diffusion and secrete surfactant to prevent alveoli from collapsing during exhalation
Respiratory Membrane
exchange oxygen and carbon dioxide by rapid diffusion and secrete surfactant to prevent alveoli from collapsing during exhalation
Lungs - Right and Left
aids in inhalation and exhalation processes and drives the exchange of carbon dioxide for oxygen to drive all bodily functions
General Structures and Regions of the Lung
- Hilum
- Apex
- Base
- Costal Surface
Hilum
site through which neurovasculature, lymphatic vessels, and airway passages enter and exit the lung
Apex
region of the lung
Base
region of the lung
Costal Surface
region of the lung
Right Lung
- lobes
a. superior
b. middle
c. inferior - horizontal fissure
- oblique fissure
Horizontal Fissure
deep groove separating the superior and middle lobes
Oblique Fissure
deep grove separating the middle and inferior lobes
Left Lung
- Lobes
a. superior
b. inferior - oblique fissure
- cardiac notch
- linguala
Oblique Fissure
deep groove separating the superior and inferior lobes
Cardiac Notch
concave region on the medial surface to accommodate the heart
Lingula
tone like projection on medial surface of the superior lobe
Pleura
double layered serous membrane that envelops each lung for protection and lubrication
1. parietal pleura
2. visceral pleura
3. pleural cavity
Parietal Pleura
protects the lungs, anchors them to the thoracic cavity and diaphragm to reduce friction during lung movements
Visceral Pleura
protects the lungs, anchors them to the thoracic cavity and diaphragm to reduce friction during lung movements
Pleural Cavity
protects the lungs, anchors them to the thoracic cavity and diaphragm to reduce friction during lung movements
Muscles of Respiration
- diaphragm
- external intercostals
- internal intercostals
- sternocleidomastoid
- scalenes
- pectoralis minor
- serratus anterior
- external oblique
- internal oblique
- rectus abdominis
Diaphragm
NERVE - phrenic nerve
CONTRACTION - inhalation
RELAXATION - passive exhalation
External Intercostals
NERVE - intercostal nerves
CONTRACTION - inhalation
RELAXATION - passive exhalation
Internal Intercostals
NERVE - intercostal nerves
CONTRACTION - assists relaxed diaphragm and external intercostals during forced exhalation
Sternocleidomastoid
NERVE - spinal accessory nerve (CN XI)
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
Scalenes
NERVE - anterior rami of cervical spinal nerves
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
Pectoralis Minor
NERVE - medial and lateral pectoral nerves
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
Serratus Anterior
NERVE - long thoracic nerve
CONTRACTION - assists contracted diaphragm and external intercostals during forced inhalation by elevating the ribs and increasing thoracic cage size
External Oblique
NERVE - anterior rami of thoracic and lumbar spinal nerves
CONTRACTION - assist relaxed diaphragm and external intercostals during forced exhalation
Internal Oblique
NERVE - anterior rami of thoracic and lumbar spinal nerves
CONTRACTION - assist relaxed diaphragm and external intercostals during forced exhalation
Rectus Abdominis
NERVE - anterior rami of thoracic and lumbar spinal nerves
CONTRACTION - assist relaxed diaphragm and external intercostals during forced exhalation
COPD (Chronic Obstructive Pulmonary Disease)
a group of lung diseases that block airflow and make it difficult to breathe
PCOS (polycystic ovarian syndrome)
hormonal disorder causing enlarged ovaries with small cysts on the outer edges
Oral Cavity
- labia (lips)
- labial frenulum
- oral vestibule
- cheeks
- oral cavity
- hard palate
- soft palate
a. uvula - palatoglossal arch
- tongue
- lingual frenulum
Labia (Lips)
open and close the anterior opening of the oral cavity
formed by orbicularis oris muscle covered by skin externally and mucosa internally
Labial Frenulum
connects the inner lip to the gums
Oral Vestibule
receives salivary secretions from the parotid glands and distributes it to the oral cavity proper
Cheeks
form the lateral walls of the oral cavity
muscles of facial expression and mastication
Oral Cavity
entrance to the digestive tract and initiation of digestion by forming the alimentary bolus and moving into the oropharynx
Hard Palate
forms the roof of the oral cavity
Soft Palate
aids in taste, swallowing, breathing, and speech
Uvula
helps close the nasal and pharyngeal passages
Palatoglossal Arch
connects the tongue to the soft palate
Palatopharyngeal Arch
connects the soft palate to the oropharynx
Tongue
forms the floor of the oral cavity
aids in different important processes such as mastication, speech, and taste
Lingual Frenulum
secures the inferior surface of the tongue to the floor of the mouth, stabilizing it during swallowing and speech
Pharynx
two layers of skeletal muscle lined with mucosa that propel food inferiorly into the esophagus
1. oropharynx
2. laryngopharynx
Esophagus
serves as a food and fluid passageway into the stomach without any digestive or absorptive functions
1. lower esophageal sphincter
Lower Esophageal Sphincter
protects the esophagus from highly acidic reflux of gastric contents
Stomach
site for temporary storage and mechanical/chemical digestion of food, transforming the food bolus into chyme
1. cardia
2. fundus
3. body
4. pylorus
a. pyloric orifice
b. pyloric sphincter
5. lesser curvature of the stomach
6. greater curvature of the stomach
7. gastric rugae (folds)
Cardia
inflow region of the stomach
Fundus
dome-shaped dilation of the stomach
Body
largest region of the stomach
Pylorus
funnel-shaped outflow region of the stomach connection to the duodenum
Pyloric Orifice
regulates the passage of gastric contents into the duodenum
thickening of smooth muscle
Pyloric Sphincter
regulates the rate of gastric emptying into the duodenum
ring of smooth muscle
Lesser Curvature of the Stomach
point of attachment for the lesser momentum connecting the stomach to the liver
Greater Curvature of the Stomach
point of attachment for the greater omentum
Gastric Rugae (Folds)
increases the surface area of mucosa in the stomach and secretes acids and enzymes
Small Intestine
- duodenum
- jejunum
- ileum
- circular folds (plicae circulares)
- ileocecal valve
Duodenum
initial portion of SI - extends from pyloric sphincter for about 10 inches, curving around the head of the pancreas
site where most of the digestive absorption of nutrients and water occurs in the gastrointestinal tract
Jejunum
middle portion of SI – continuous with the duodenum and ileum
site where most of the digestive absorption of nutrients and water occurs in the gastrointestinal tract
Ileum
terminal portion of the SI
site where most of the digestive absorption of nutrients and water occurs in the gastrointestinal tract
Circular Folds (Plicae Circulares)
deep transverse folds in SI
force chyme to spiral and slow down as it passes through the small intestine, increasing absorption of nutrients
Ileocecal Valve
sphincter created by the protrusion of smooth muscle of the ileum into the lumen of the cecum
controls the passage of contents from the ileum to the cecum
Large Intestine
responsible for absorption of electrolytes and water, formation, temporary storage, and elimination of feces, and housing the gut microflora
1. cecum
a. vermiform appendix
2. ascending colon
3. right colic (hepatic) flexure
4. transverse colon
5. left colic (splenic) flexure
6. descending colon
7. sigmoid colon
8. rectum
9. anal canal
10. internal anal sphincter
11. external anal sphincter
12. anus
13. teniae coli
14. haustra
15. epiploic (omental) appendages
Cecum
first portion of LI
site for temporary storage of intestinal contents and fluid and electrolyte reabsorption
Ascending Colon
fluid and electrolyte reabsorption, formation of fecal matter
Right Colic (Hepatic) Flexure
fluid and electrolyte reabsorption, formation of fecal matter
Transverse Colon
fluid and electrolyte reabsorption, formation of fecal matter
Left Colic (Splenic) Flexure
fluid and electrolyte reabsorption, formation of fecal matter
Descending Colon
fluid and electrolyte reabsorption, formation of fecal matter
Sigmoid Colon
fluid and electrolyte reabsorption, formation of fecal matter
Rectum
temporary storage of fecal matter and defecation
Anal Canal
temporary storage of fecal matter and defecation
Internal Anal Sphincter
thickening of smooth muscle
temporary storage of fecal matter and defecation
External Anal Sphincter
skeletal muscle
temporary storage of fecal matter and defecation
Anus
temporary storage of fecal matter and defecation