Lab 6 Flashcards

1
Q

Correct term for host range of Hepatozoonosis

A

Obligate heteroxenous

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2
Q

In which cells do gamonts of Hepatozoon develop?

A

Neutrophil granulocytes (monocytes)

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3
Q

Which form of Hepatozoon canis can be found in the neutrophil granulocytes?

A

Gamonts (elliptic, 8-12 micro m)

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4
Q

What is the vector of Hepatozoon canis?

A

a. Flea b. Lice c. Fly d. Other

Svar: brown dog tick (Rhipicephalus sanguineus)

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5
Q

(Not past Q)

What’s the clinical signs of hepatozoonosis?

A
  • Asymtomatic
  • or fever, lethargy, anorexia, emaciation, anaemia, swelling of LN, nasal discharge, weakness of limbs, muscle pain, bloody diarrhoea, death
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6
Q

(Not past Q)

Parasitological diagnostic of hepatozoonosis?

A

Blood smear - check gamonts in neutrophils (monocytes)

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7
Q

(Not PQ)

What’s the necroscopic findings in hepatozoonosis?

A

Infected organs shows inflammatory infiltrates, necrosis

Histology:
Schizont, nuclei in periphery

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8
Q

Symptom not in dog affected with Babeiosis:

A

Abortion

but it may occur in cows

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9
Q

(not PQ)

Which species of Babesia do we have?

A
  • Babesia caballi (Eq)
  • B. Divergens, B. bovis, B. Bigemina, B. major (cattle)
  • B. Canis, B. vogeli, B. gibsoni (dog)
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10
Q

(not PQ)

How is babesiosis transmitted?

A

tick infestation

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11
Q

Animal that aborts foetus in Babeiosis:

A

Cow

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12
Q

In which animal does Babeiosis infection affect the eyes? (clinical sign)

A

Dog (keratitis and iridocyclitis)

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13
Q

Which Babesia has zoonotic significance?

A

B. bingemina -> More pathogenic, should be the correct answer
B. divergans of cow -> Stated in notes

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14
Q

What is the difference between the cell preference of Babesia and Theileria?

A

Theileria can develop in lymphocytes, Babesia does not

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15
Q

What symptom does not belong to the common symptoms of Babeiosis of dog?

A

Abortion

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16
Q

Which host may show clinical signs in the eye during Babesia infection?

A

Dog

They get keratitis and iridocyclitits when infected with B. canis, B. vogeli, or B. gibsoni

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17
Q

What is the species of Babesia that have zoonotic character?

A

B. divergens of cow

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18
Q

What type of animals does Babeiosis affect?

A

Mammals

19
Q

Which species do not have haemoglobinuria as a clinical sign of Babeiosis?

A

Horses

20
Q

Babesia vogeli can infect:

A

Dogs

21
Q

Which cells does Babesia first infect?

A

RBCs

22
Q

Which species can occur in cattle?

A

B. divergans (and b.bovis, b. major, B. bigemina)

23
Q

Which is ‘small babesia’?

A

B. canis (? står b. divergens i dok)

24
Q

(not PQ)

Parasitological diagnosis in Babesia?

A
  • detect piroplasms in RBCs films stained with Giemsa
  • Small babesia (< 3 micro m): appears near edge of cells in pairs; eg. b. divergens
  • Large babesia (3-5 micro m): paired at acute angle in red cells; eg. b. bigemina
25
Q

(not PQ)

Serodiagnostic methods diagnosis in Babesia?

A

ELISA, IFAT, CFT

  • Can also transfuse blood into slenectomized animals- detection of parasites in blood smear
26
Q

(not PQ)

What is the necroscopic findings of Babesia?

A
  • anaemia, jaundice, splenomegaly
  • sub-epicardial and sub-endocardial haemorrhages
  • red and brownred urine in bladder
  • degeneration of liver and kidney
  • catarrh with petechiae in GI mucosa
27
Q

Theileria develops where first?

A
  • Lymphocytes in the lymph nodes (Koch’s bodies in lymphocytes)
  • RBCs (merozoites found in blood)
28
Q

Form of Theileria that occurs in RBCs:

A

Piroplasm (? nei, står merozoites)

29
Q

What is the difference between the cell preference of Babesia and Theileria?

A

Theileria can develop in lymphocytes, Babesia does not

30
Q

In what cells do the Koch bodies develop?

A

Lymphocytes

31
Q

Theleria annulata is seen in which species?

A

Cattle

32
Q

What is the size of Koch bodies?

A

10 – 12 um

33
Q

Koch bodies are:

A

Schizonts in WBCs (? står ikke, kanskje fra lecture?)

34
Q

(not PQ)

Necroscopic findings in Theileria:

A
  • Hemorrhages in serous and mucous membranes
  • Swelling of LN and spleen
  • Ulcers in abomasum and intestine, pulmonary oedema, cachexia (in chronic cases)
35
Q

Vertebrate animals susceptible to Encephalitozoonosis:

A

Many mammals (Rabbits (especially), Rodents, Carnivores, Primates)

36
Q

Which staining can’t you use in the detection of Encephalitozoa?

A

HE staining

Can use PAS, Gram +, Ziehl Neelson, and Indian ink for the spores

37
Q

In Encephalitozoonosis, eye disorders are seen in which species?

A

Fox and Dog

Iritis, Keratitis and blindness

38
Q

During the necropsy, thickened and nodular vessels in arteries of viscera can
be seen with the naked eye in:

A

Encephalitozoonosis

39
Q

Spores of E. cuniculi can be detected where in rabbits?

A

In the urine

40
Q

What size are the Encephalitozoon spores?

A

1.5 x 2.5 um Elliptical or Oval

41
Q

Which staining is used for Encephalitozoonosis?

A

Gram + (also PAS+ and ZN+)

42
Q

What kind of organ is affected by Encephalitozoon cuniculi?

A

Kidney

43
Q

(Not PQ)

What are the clinical signs in Encephalitozoonosis?

A
  • Usually asymptomatic
  • rabbits: neurological sign, torticollis or wry neck, paralysis and seizures
  • Dogs and foxes: iritis, keratitis, blindness
44
Q

(Not PQ)

How do you detect Encephalitozoonosis?

A
  • Detect spores in urine of rabbits (microscopic examination)
  • Histology of brain: multifocal granulomatous encephalitis - infiltrated by lymphocytes, necrotic foci surrounded by macrophages and lymphocytes
  • Histology of kidney: chronic intestinal nephritis
  • Thickened and nodular vessels in arteries of viscera (esp. superficial coronary arteries) - seen w/ naked eye