Lab 5 Cartilage Flashcards

1
Q

The most prevalent cartilage in vertebrates

A

Hyaline cartilage

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2
Q

Where in synovial joints is hyaline cartilage found

A

At the articular surface (knee and shoulder)

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3
Q

This tissue is resilient and can withstand compressive force

A

Hyaline cartilage

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4
Q

Trachea is an example of what cartilage

A

Hyaline

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5
Q

Is hyaline cartilage ECM vascular

A

No

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6
Q

What kind of fibers are embedded in the ground substance of the hyaline ECM

A

Type 2 collagen fibers

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7
Q

Why does hyaline cartilage have a basophilic stain

A

Sulfate groups on proteoglycans attract basic dyes

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8
Q

How many layers is the perichondrium

A

2 layers

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9
Q

What is the outer layer of perichondrium made of

A

DICT (type 1 collagen)

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10
Q

What cells are in the outer layer of perichondrium

A

Fibroblasts

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11
Q

Describe inner layer of perichondrium

A

Inner layer is chondrogenic and has 2-3 layers of flat, fibroblast-like chondrogenic cells

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12
Q

These cells have the capacity to become Chondroblasts

A

Chondrogenic cells

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13
Q

Young cartilage cells that are more round than perichondrial cells and are in the inner perichondrium layer

A

Chondroblasts

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14
Q

What secretes the ECM and what does it eventually become

A

Chondroblasts secrete the ECM and become chondrocytes

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15
Q

During tissue prep, chondrocytes retract from …… leaving gaping holes

A

Lacunae

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16
Q

Daughter cells of mitotic division that are clustered chondrocytes

A

Isogenous groups

17
Q

ECM immediately enveloping chondrocytes

A

Territorial matrix

18
Q

Wide space of ECM

A

Interterritorial space

19
Q

The structure of elastic cartilage is similar to hyaline cartilage except that the ECM contains

A

The ECM contains elastic fibers

20
Q

What synthesizes elastic fibers

A

Chondrocytes

21
Q

Is elastic cartilage vascular in adults

A

No

22
Q

True or false: Fibrous cartilage is vascular

A

False, it is avascular

23
Q

T/F: fibrocartilage has a perichondrium

A

False

24
Q

Fibrocartilage is a hybrid tissue, meaning:

A

It has dense connective tissue and hyaline cartilage

25
Q

What type of collagen does the fibrocartilage ECM have

A

Type 1 and 2 collagen

26
Q

Does fibrocartilage have a lot of PGs

A

Fibrocartilage has a low concentration of proteoglycans

27
Q

Fibrocartilage has good tensile strength T/F

A

True

28
Q

Fibrocartilage lies between

A

Hyaline cartilage and dense connective tissue

29
Q

In vertebrates, most skeletal elements from the neck down form by

A

Endochondral Ossification

30
Q

The resting zone is …

A

Unaffected by EO and randomly scattered with chondrocytes

31
Q

Zone of proliferation

A

Stacking chondrocytes

32
Q

Zone of hypertrophy

A

Swelling chondrocytes

33
Q

Zone of degradation

A

One terminal hypertrophic layer facing trabecular bone and marrow

34
Q

Zone of ossification

A

Trabecular bony spicules with hypertrophic cartilage cores

35
Q

Osteoclasts are derived from

A

Monocytes lineage and are multinucleate

36
Q

Howship’s lacunae

A

Resorption pits contain osteoclasts present on trabecular bone

37
Q

Bone-resorbing cells in zone of ossification

A

Osteoclasts