Lab 10 Flashcards
1
Q
A person has a balanced translocation between chromosomes 7 and 21. Would it be possible for this individual to produce a child with a normal karyotype? Explain.
A
Yes, if the child caries normal chromosomes 7 and 21
2
Q
What is the normal number of chromosomes in humans?
A
46 total chromosomes
3
Q
Explain the mechanism that caused abnormal chromosome numbers in THP-1 and U936 cells?
A
The cells lack an error checking ability which causes the cell cycle to continue at a rapid rate
4
Q
Describe a genetic disorder caused by an abnormal chromosome.
A
Down syndrome - extra copy of chromosome 21
5
Q
At which stage of mitosis are the chromosomes in their most condensed state and are best suited for karyotyping?
A
During metaphase
