L9 Bone Marrow Flashcards

1
Q

ID the cell

A

Proerythroblast

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2
Q

ID the cell

A

Metamyelocyte

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3
Q

ID the cells

A

Lymphoblasts

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4
Q

ID the cell

A

Band neutrophil

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5
Q

ID cells a, b, e, & f

A

a. promyelocyte
b. neutrophilic myelocyte
e. neutrophilic band cell
f. segmented neutrophil

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6
Q

ID the cell

A

promyelocyte

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7
Q

ID the cell

A

monocyte

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8
Q

ID the cell

A

metamyelocyte

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9
Q

Identify the smear.

Identify the stain.

A

Bone marrow aspirate.

Giemsa or Wright stain.

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10
Q

Outline the stages of erythropoiesis shown here.

A
  1. myeloid precursor
  2. proerythroblast (aka pronormoblast)
  3. basophilic erythroblast/normoblast
  4. polychromatic erythroblast/normoblast
  5. orthochromatic erythroblast/normoblast
  6. reticulocyte (aka polychromatic erythrocyte)
  7. erythrocyte
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11
Q

ID the cell

A

Reticulocyte

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12
Q

ID the cell

A

Polychromatic erythroblast

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13
Q

I cells b, c, d, e, & g

A

b. neutrophilic metamyelocyte
c. band neutrophil
d. segmented neutrophil
e. segmented neutrophil
g. neutrophilic metamyelocyte

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14
Q

Name the cell indicated by the red arrow #1

Name the cell indicated by the red arrow #2

Name the stain used in the top image.

Name the stain used in the bottom image.

A

Both are polychromatic erythrocytes.

Top half: Giemsa/Wright stain

Bottom half: supravital stain (new methylene blue or cresyl violet)

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15
Q

Identify the whole tissue.

  1. Identify structure labeled with the star *
A

Tissue: Bone Marrow

* = bony trabeculae

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16
Q

Name cells a & b

A

a. basophilic erythroblast
b. polychromatic erythroblast

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17
Q

ID the cell

A

Segmented neutrophil

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18
Q

ID the cell

A

myeloblast

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19
Q

ID the cell

A

monocyte

20
Q

ID the cell

A

Band cell (neutrophil)

21
Q

Name the stages of development shown here.

A
  1. proerythroblast (aka pronormoblast)
  2. basophilic erythroblast/normoblast
  3. polychromatic erythroblast/normoblast
  4. orthochromatic erythroblast/normoblast
  5. reticulocyte (aka polychromatic erythrocyte)
  6. erythrocyte
22
Q

Give the M:E ratio of the following images.

A

1: 3 = erythroid hyperplasia
11: 4 = myeloid hyperplasia
3: 1 would be normal

23
Q

Name the cells ‘a’.

These cells will have lots of ______.

A

Basophilic erythroblasts; ribosomes (for synthesizing heme)

24
Q

ID the cell

A

Myelocyte

25
Q

ID the cell

A

metamyelocyte

26
Q

Identify the sample.

A

Bone marrow biopsy.

27
Q

ID the cell

A

myeloblast

28
Q

ID cells 1, 2, 3, & 4

A

1- myelocytes,

2- band forms,

3- early segmented neutrophil,

4 – segmented neutrophils

29
Q

Identify the cell.

What is the brown substance in the slide?

A

Nurse cell macrophage.

Iron.

30
Q

ID the cell

A

promyelocyte/progranulocyte

31
Q

ID the cell

A

Segmented cell (neutrophil)

32
Q

ID the big cells

A

Monoblasts

33
Q

Name the 6 stages of granulocyte development shown here. Which stages have primary vs secondary granulocytes?

A
  1. myoblast
  2. promyelocyte (primary)
  3. myelocyte (mixed)
  4. metamyelocyte (secondary)
  5. band NEUTROPHIL (secondary + tertiary)
  6. mature segmented cell
34
Q

ID the cell

A

Orthochromatic erythroblast

35
Q

Identify the whole tissue.

  1. Identify cells labeled I
  2. Identify cells labeled II
  3. Identify cells labeled III
A

Tissue: Bone Marrow

  1. Megakaryocytes
  2. Adipose Cells
    1. These increase in proportion with age
  3. Venous Sinusoids
    1. Notice the RBCs
36
Q

Identify the tissue.

  1. Identify cells I
  2. Identify cells II
A

Bone marrow.

  1. erythroid precursors
  2. megakaryocytes
37
Q

ID the cell

A

Basophilic erythroblast

38
Q

Identify the whole tissue.

Identify the stain used.

Identify the indicated cells.

A

Spleen.

H&E stain.

Megakaryocytes. These don’t belong here: extramedullary hematopoiesis!

39
Q

Name cells a-c

A

a. basophilic erythroblast
b. polychromatic erythroblast
c. polychromatic erythroblast

40
Q

ID cells a, b, d, k, and h

A

a. promyelocyte
b. neutrophilic myelocyte
d. promyelocyte
k. myeloblast
h. band neutrophil

41
Q

Name cells A-D

A

A. Proerythroblasts (notice finer chromatin)

B. Basophilic erythroblasts

C. Polychromatic erythroblasts

D. Orthochromatic erythroblasts

42
Q

ID the cell

A

myelocyte

43
Q

Identify the whole tissue and:

  1. Identify structure I
  2. Identify cell type II
  3. Identify cells III
  4. Identify cell group IV
A

Tissue: Bone Marrow

  1. bony trabeculae
  2. granulocytes
  3. macrophages
  4. erythroid island
44
Q

ID the cell

A

erythrocyte

45
Q

Name cells a-c

A

a. polychromatic erythroblast
b. orthochromatic erythroblast
c. basophilic erythroblast