L8: PPG, teichoic acid, LPS Flashcards
LPS uses what mechanisms?
ABC transporter and Wzy mechanism
PPG uses which mechanism?
Wzy mechanism
T/F Gram-negative contain an outer membrane?
True
NAG/NAM linked by carbohydrate polymers and cross linked peptide chains
PPG structure and monomers
Structure before lipid cycles on ppg synthesis
Parks nucleotide
Assembly, transport, polymerization
PPG synthesis
Activated muramic acids use ATP to assemble Park’s nucleotide
Assembly
Lipid I and II move across the membrane to be polymerized
Transport
Occurs in the extracellular space, linking of peptides
Polymerization
On surface of gram-positive cell walls, help maintain structure to ppg, covalently liked to ppg layers
Teichoic acid
Spans ppg layer and is covalently linked to plasma membrane
Lipoteichoic acid
Found on gram-negative bacteria, O side chain, polysaccharide core, lipid A head
Lipopolysaccharide (LPS)
Three known pathways
wzy dependent, ABC-transporter dependent, synthase-dependent
Three known pathways
wzy dependent, ABC-transporter dependent, synthase-dependent
Involves hetero and branched polysaccharides, does not require energy
Wyz dependent