L8 - Cerebral Disorders Flashcards
What are some life events associated with older life?
Retirement - critical transition
Grandparenting - can have positive and negative afffectis - higher depression, diabetes, insomnia, stress…
Bereavement - Older people cope better with loss. Maybe because loss is expected, or they have better social connections than a young person.
OR … things such as insomnia, loss of appetite are overlooked in old people b/c it looks like general aging
What are signs of normal memory decline in ageing?
- decrease in amount of new information remembered
- lapses in memory
- difficulty with complex attentional tasks
- CELL VOLUME IN HIPPOCAMPUS DECLINES WITH AGE
What are some DSM-V neurocognitive disorders?
NOT AGE SPECIFIC.
- Alzheimers
- Huntington’s
- Parkinson’s
- Traumatic brain injury
What -are- neurocognitive disorders?
They are referred to as dementia, delirium and amnestic disorders.
They are
- syndromes with UNDERLYING PATHOLOGY
- not just degenerative disorders, also disorders that affect young people
What are the stages of dementia?
Pre-clinical
MCI - Mild cognitive impairment
DEMENTIA
What is pre-clinical dementia?
This precedes MCI, and is almost indistinguishable from normal ageing.
also includes people who have demonstrated subtle decline from their own baseline that exceeds typical ageing, but haven’t met the criteria for MCI
Describe Alzheimer’s Disease?
- Memory loss disrupts daily life
- Difficulty planning/solving problems
- Difficulty completing familiar tasks at home/work/for leisure
- Confusion with time and place
- trouble understanding visual images and spatial relationships
- new problems with words in speaking or writing
- misplacing things
- poor judgement
- changes in mood and personality
- withdrawal from work or social activities
What are the stages of decline in dementia?
Early dementia
Moderate dementia - similar symptoms as from stress or illness and side effects from medication - often misdiagnosed
Advanced dementia
Describe Early dementia.
–> Insidious onset
- apathy
- loss of interest in hobbies
- irritable
- poor judgement
- unwilling to try new things
- forgetful of details of recent events
- blaming others for ‘stealing’ lost items.
Describe moderate dementia.
–> problems become more apparent and disabling. Need more help from others
- more forgetful of recent events
- forget names of family and friends
- confused regarding time and place
- lost if away from familiar surroundings
- repetitiveness
- neglectful of hygiene and eating
- see or hear things that are not there
- behave inappropriately
Describe advanced dementia.
Person is SEVERELY disabled and needs TOTAL care.
- be unable to remember occurrences for even a few minutes
- lose ability to understand/use speech
- difficulty walking
- need help eating, bathing, toileting
- aggressive
- restless
- fail to recognise everyday objects
- no recognition of friends and family
- uncontrolled movements/immobility
Where are areas that show deterioration of the brain in dementia?
- enlarged ventricles
- language area
- memory area
- deeper sulci
What is the most common type of dementia?
Alzheimer’s
What is vascular dementia?
Dementia caused by reduced blood supply to the brain due to diseased blood vessels.
–> heart problems –> due to diet? so some change can be achieved if changes made to diet.
(blood is delivered to the brain through vascular system)
vascular system damaged (leaked/blocked) –> blood can’t reach brain –> brain cells die –> memory and cognition problems.
- effects of brain cell death can be subtle at first, but builds up.
What does the course of decline for vascular dementia look like, when compared to alzheimer’s?
it is a gradual step-wise deterioration.
The decline is a little more steep, and only takes 6-8 years.
What is parkinson’s disease?
A progressive disease marked with tremor, muscular rigidity and slow movement.
- Associated with degeneration of the basal ganglia of the brain and deficiency of DOPAMINE
- 50-80% of these people go to develop dementia: