L72 + 73 Flashcards
Most common site for ectopic pregnancy
Tube - ampulla
RFs ecoptic
Use assisted repro tech Prev tube surg // ectopic Infections (PID) Endometriosis Smoking
Presentation of ectopic
Ab pain + skipped period + vag bleeding
Symptoms/vitals will depend on amt of blood loss
How should BhCG change during a normal preg
Double every 48 hrs (66%)
What BhCG means you should be able to see a fetus in the uterus?
> 1500
Treat ectopic
MTX - f/u for BhCG fall Lapro = treat 1. Salpingostomy = remove ectopic 2. Salpinectomy = remove tube D&C - certain det of uterine preg (when don't see fetus on US)
What molecule normally suppresses delivery?
Progesterone -> increase CRH in bound form
Suppress production of ACTH (pit) and cortisol + DHEA (adrenal cortex)
Describe physiology of contractions
Less CRH More ATCH from ant pit -> says adrenals produce 1. Cortisol -> PGE 2. DHEA -> E (now E > P) Changes in the myometrium
How does pre-term birth happen?
Some inflam triggers the normal physiology to start early
TESTQ: what is the def of pre-term labor
Regular uterine contractions causing cervical change before 37 wks
RF pre-term birth
Prev pre-term birth
Multiple kids
Bleeding in preg
What is fetal fibronetin
Swab vagina - amniotic fluid will form crystals on slide
High NEGATIVE predict value - don’t see it, you’re not having pre-term labor
Positive doesn’t tell you anything
Treat pre-term birth
Delay to 34 wks
- IV fluid bolus - if dehydrated, will start contractions
- Tocolysis
- Steroid - promote lung maturity
- Mg - neuro protective in baby
- Grp B strep if you’re moving towards delivery
Meds to stop pre-term labor
Tocolysis
Mg
Nifedipine = Ca CB
Indomethacin = block PG, going to close PDA
CI to tocolysis
Infection - just deliver
Sig vag bleeding
After 34 wks - just deliver