L6.1. CT: Image Formation and Reconstruction Flashcards

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1
Q

What is CT?

A

Computed Tomography

A volumetric imaging modality based on X-ray absorption

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2
Q

CT allows for what?

A

Reconstruction of a 2D or 3D absorber map

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3
Q

Who invented CT?

A

Sir Godfrey Hounsfield

At the laboratories of EMI Limited

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4
Q

What does ‘Data Acquisition’ refer to?

A

The collection of X-ray transmission measurements through the patient

Requires an X-ray source that produces an X-ray beam, which is collimated into the shape of a fan or cone

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5
Q

Aim of CT

A

Obtain a specially resolved map of absorption coefficients in one slice of the patient’s body

The map, if sampled at a finite resolution, gives an image

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6
Q

The reconstruction of images from the X-ray measurements involve..

A

Various steps

The result is a 2D matrix of preselected size and detail

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7
Q

CT vs Conventional plain film radiography

A

CT has better contrast

CT has worse spatial resolution

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8
Q

When was the first CT scan of a patient?

A

1st October, 1971

Atkinson Morley’s Hospital, London.

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9
Q

CT is the first imaging modality where the what is essential to the image reconstruction?

A

The computer

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10
Q

How fast can a 2D cross-sectional image be produced?

A

Less than a second

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11
Q

How much do Clinical CT scanners cost?

A

Millions

-> relatively high cost per CT scan

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12
Q

In a projection image, like a standard X-ray projection image, what cannot be determined?

What is done to solve this?

A

The exact location of interest

Radiologist often take 2 perpendicular projections
Eg lateral and AP

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13
Q

AP

A

Anterior-posterior

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14
Q

One possible geometry for CT scanner source and detectors

A

Arc shaped-detector

Source and detector rotate in tandem

Recording projections through a single plane within the body
-> for many different angles

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15
Q

When an x-ray beam passes through an object, what happens?

A

Some photons are absorbed or scattered

X-ray attenuation/transmission

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16
Q

Reduction of x-ray attenuation depends on?

A

Atomic composition of the crossed tissues

Density of the crossed tissues

Energy of the photons

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17
Q

What happens to the partially attenuated x-rays after passing through an object?

A

They are collected by x-ray detectors on the opposite side

Then converted from x-rays photons -> electrical signals

Signals then converted into digital data, then attenuation value is calculated

18
Q

S1

A

µ1 + µ2

19
Q

S2

A

µ3 + µ4

20
Q

S4

A

µ1 + µ3

21
Q

S3

A

µ2 + µ4

22
Q

What law does each projection follow?

A

Lambert Beer’s Law

We obtain a linear equation system due to this that we can solve for µ1, µ2, µ3, µ4

23
Q

Attenuated beams symbols

A

I1, I2, I4, I5

24
Q

When can the simple equation system be solved?

A

When one of the absorption coefficients is known

25
Q

Image reconstruction steps

A
  1. Measurements
  2. Pre-processing
  3. Raw Data
  4. Filtering
  5. Filtered Data

6.1. Interpolation
6.2. Back-projection

  1. Axial Source images
26
Q

What is the selected ‘field of view’ divided into?

A

Small image elements aka pixels

27
Q

What do pixels that make up each cross-sectional represent?

A

Small volume of tissue

Called a voxel (volume element)

28
Q

Density value of each pixel depends on

A

The composition of the tissue it represents

Expressed in Hounsfield Units (HU)

29
Q

How are HU calculated?

A

From the attenuation measurements relative to the attenuation of water

30
Q

HU range

A

-1024 to +3071 HU

31
Q

Lung HU

A

-500

32
Q

Fat HU

A

-100 to -50

33
Q

CSF HU

A

+15

34
Q

Blood HU

A

+30 to +45

35
Q

Muscle HU

A

+10 to +40

36
Q

Adrenal tumor HU

A

Less than +10

37
Q

White matter HU

A

+20 to +30

38
Q

Grey matter HU

A

+37 to + 45

39
Q

Liver HU

A

+40 to +60

40
Q

Bone HU

A

+700 to +3000

41
Q

Air HU

A

-1000