L6.1. CT: Image Formation and Reconstruction Flashcards

1
Q

What is CT?

A

Computed Tomography

A volumetric imaging modality based on X-ray absorption

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2
Q

CT allows for what?

A

Reconstruction of a 2D or 3D absorber map

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3
Q

Who invented CT?

A

Sir Godfrey Hounsfield

At the laboratories of EMI Limited

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4
Q

What does ‘Data Acquisition’ refer to?

A

The collection of X-ray transmission measurements through the patient

Requires an X-ray source that produces an X-ray beam, which is collimated into the shape of a fan or cone

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5
Q

Aim of CT

A

Obtain a specially resolved map of absorption coefficients in one slice of the patient’s body

The map, if sampled at a finite resolution, gives an image

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6
Q

The reconstruction of images from the X-ray measurements involve..

A

Various steps

The result is a 2D matrix of preselected size and detail

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7
Q

CT vs Conventional plain film radiography

A

CT has better contrast

CT has worse spatial resolution

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8
Q

When was the first CT scan of a patient?

A

1st October, 1971

Atkinson Morley’s Hospital, London.

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9
Q

CT is the first imaging modality where the what is essential to the image reconstruction?

A

The computer

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10
Q

How fast can a 2D cross-sectional image be produced?

A

Less than a second

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11
Q

How much do Clinical CT scanners cost?

A

Millions

-> relatively high cost per CT scan

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12
Q

In a projection image, like a standard X-ray projection image, what cannot be determined?

What is done to solve this?

A

The exact location of interest

Radiologist often take 2 perpendicular projections
Eg lateral and AP

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13
Q

AP

A

Anterior-posterior

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14
Q

One possible geometry for CT scanner source and detectors

A

Arc shaped-detector

Source and detector rotate in tandem

Recording projections through a single plane within the body
-> for many different angles

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15
Q

When an x-ray beam passes through an object, what happens?

A

Some photons are absorbed or scattered

X-ray attenuation/transmission

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16
Q

Reduction of x-ray attenuation depends on?

A

Atomic composition of the crossed tissues

Density of the crossed tissues

Energy of the photons

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17
Q

What happens to the partially attenuated x-rays after passing through an object?

A

They are collected by x-ray detectors on the opposite side

Then converted from x-rays photons -> electrical signals

Signals then converted into digital data, then attenuation value is calculated

18
Q

S1

19
Q

S2

20
Q

S4

21
Q

S3

22
Q

What law does each projection follow?

A

Lambert Beer’s Law

We obtain a linear equation system due to this that we can solve for µ1, µ2, µ3, µ4

23
Q

Attenuated beams symbols

A

I1, I2, I4, I5

24
Q

When can the simple equation system be solved?

A

When one of the absorption coefficients is known

25
Image reconstruction steps
1. Measurements 2. Pre-processing 3. Raw Data 4. Filtering 5. Filtered Data 6.1. Interpolation 6.2. Back-projection 7. Axial Source images
26
What is the selected ‘field of view’ divided into?
Small image elements aka pixels
27
What do pixels that make up each cross-sectional represent?
Small volume of tissue Called a voxel (volume element)
28
Density value of each pixel depends on
The composition of the tissue it represents Expressed in Hounsfield Units (HU)
29
How are HU calculated?
From the attenuation measurements relative to the attenuation of water
30
HU range
-1024 to +3071 HU
31
Lung HU
-500
32
Fat HU
-100 to -50
33
CSF HU
+15
34
Blood HU
+30 to +45
35
Muscle HU
+10 to +40
36
Adrenal tumor HU
Less than +10
37
White matter HU
+20 to +30
38
Grey matter HU
+37 to + 45
39
Liver HU
+40 to +60
40
Bone HU
+700 to +3000
41
Air HU
-1000