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MEDICAL BACTERIOLOGY > L6 Sexually Transmissible Diseases > Flashcards

L6 Sexually Transmissible Diseases Flashcards

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USMLE® Step 1 flashcards
1
Q

Transmission of STIs

A

Require close contact (sexual)

Via contaminated blood (Syphilis)

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2
Q

Risk factors

A 
Age (16-24)
Institutionalisation 
New sexual partner
Multiple sexual partners
Sex abroad or sex tourism 
MSM (gay)
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3
Q

Gonorrhoea organism

A

Meisseria gonorrhoea

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4
Q

Men and women statistics of gonorrhoea

A

2nd most common STI in UK
Men peak at 20-24yrs
Women peak at 16-19yrs

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5
Q

Symptoms of gonorrhoea

A 
Discharge of pus
Burning sensation 
Testicular and scrotal pain 
Anal itching and bleeding 
Sore throat 
Non-genital complications
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6
Q

Complications of gonorrhoea

A

Disseminated genecoccal infection
Pelvic inflammatory disease
In men = orchitis/ epididymitis/ sterility
Ophthalmia neonatorum

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7
Q

Pathogenesis of gonorrhoea

A

Good at evading human response

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8
Q

Lab diagnosis of gonorrhoea

A

Specimen types = swab/ urine

Test types = microscopy/ culture/ NAAT

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9
Q

Treatment of gonorrhoea

A

Current = ceftriaxone injection (1g)
Alternative = oral cefixime and azithromycin
Super gonorrhoea
Contact tracing is vital

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10
Q

Chlamydia trachomatis

A

Commonest STI in UK

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11
Q

Symptoms of C. trachomatis

A

Indistinguishable from those of gonorrhoea

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12
Q

Lab diagnosis of C. trachomatis

A

Specimen type = swab/ urine

Test type = NAAT/ cell culture (rarely used)

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13
Q

Treatment of C. trachomatis

A

Deoxycycline (100mg 2 times a day

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14
Q

Treatment of C. trachomatis

A

Deoxycycline (100mg 2 times a day for 7 days)

Azithromycin (1g single dose - followed up by 500mg once daily for 2 days after)

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15
Q

Mycoplasma genitalium

A

“The new chlamydia”
Similar presentation to chlamydia and gonorrhoea
Slow uptake on diagnostic testing (NAAT)
Treatment with moxifloxacin (antibiotic resistance)

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16
Q

Syphilis organisms

A

T. pallidum pallidum

17
Q

Syphilis stages

A 
Primary = chancre
Secondary = generalised malaise/ condylomata lata
Tertiary = gumma/ cardiovascular lesion/ general paresis of  insane
18
Q

Syphilis diagnosis

A

Serology methods almost exclusively used

  1. Treponemal antibodies (remain +ve for life)
  2. Non-treponemal antibodies (decline following treatment)
19
Q

Lymphogranuloma venereum

A

Caused by severs L1, L2, L3 of C. trachomatia

Infection of lymph nodes

20
Q

Chancroid

A

Haemophilis ducreys
Lesions are extremely painful
Lymph node swelling
Hard to tell different between them all

21
Q

Donovanosis

A

Klebsiella inguinale

22
Q

Bacterial vaginosis

A

Reduction in dominant lactobacilli in vagina and increase in other organisms
Risk factor = multiple sexual partners
Diagnosis = clue cells/ whiff test

MEDICAL BACTERIOLOGY (8 decks)

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