L6- Advances in vaccines against malaria

Question 1

Describe the life cycle of P.falciparum malaria

Answer 1

Slide 3

Question 2

Give some malaria prevention strategies.

Answer 2

Slide 4

Question 3

Guve 5 strategies for malaria immune intervention.

Answer 3

Slide 5

Question 4

What are two vaccine development strategies for malaria and why has a malaria vaccine been elusive?

Answer 4

Slide 6-7

Question 5

Describe the pre-erythrocytic stages of malaria infection. How can this stage be targeted?

Answer 5

-pre-erythrocytic stages: sporozoite and liver-stage

Slide 9-12

Question 6

Discuss malaria subunit vaccines.

Answer 6

Slide 13-16

Question 7

Describe an antibody approach against sporozoite.

Answer 7

Slide 17

Question 8

Discuss liver-stage vaccines.

Answer 8

Slide 18

Question 9

Discuss transmission-blocking vaccines.

Answer 9

Slide 19-21

Question 10

Discuss the erythrocytic stage of malaria. How can this stage be targeted?

Answer 10

Slide 22-48

Question 11

Discuss the challenges of developing vaccines against a different malaria-causing pathogen, P.vivax.

Answer 11

Slide 49-52