L5 The Cerebellum and Motor Learning Flashcards

1
Q

Role of Cerebellum

A
  • Maintenance of balance and posture
  • Coordination of voluntary movements
  • Motor learning
  • Cognitive functions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name the cerebellar peduncles and their function

A

Superior
Middle
Inferior

connect the cerebellum to the midbrain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Divisions of the cerebellum

A

Vestibulocerebellum
Spinocerebellum
Cerebrocerebellum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Vestibulocerebellum

  • location
  • function
  • pathway
A

-in the flocculonodular lobe
-contains vestibular nuclei involved with balance and eye movements
bypassed deep motor neuron
Inputs-semicircular canals of the ear, afferent input from vestibular nerve

Outputs

  • sends fibres to the vestibular nuclei
  • Medial vestibular nuclei leads to vestibulospinal tract
  • Lateral vestibular nuclei branches at synapse at extra-occular muscle nuclei
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Spinocerebellum

  • structure
  • function
A

comprises vermis and paravermis

Vermis comprises fastigial nucleus (medial descending systems)

Paravermis comprises interposed nucleus (lateral descending systems)

Function- motor execution/coordination (controls muscle tone and posture)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Spinocerebellum pathways

A

input: spinocerebellar tracts

outputs:
rubrospinal tracts
reticulospinal tracts vestibulospinal tracts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cerebrocerebellum

A

Comprises lateral hemispheres and dentate nucleus (communicates with cortical areas 4+6)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cerebrocerebellum pathways

A

Input from

  • corticopontine tract (primary motor cortex to pontine nuclei)
  • pontocerebellar tract (pontine nuclei to cerebellar cortex)

Output

  • cortex
  • dentate nuclei
  • thalamic nuclei
  • primary motor cortex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe the lobar anatomy of cerebellum

A
Vermis
fastigial nucleus (lat descending pathway-motor execution)
Paravermis
interposed nucleus (lat descending pathway-motor execution)

Hemisphere
contains dentate nucleus (cortical areas 4&6, motor planning)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Dysmetria

A

Type of ataxia
improper measuring of distance in muscular acts

-hypermetria is overreaching (overstepping)
-hypometria is underreaching (understepping)
movement not stopped in time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dyssynergia

A

decomposition of complex movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dysdiadochokinesia

A

reduced ability to perform rapidly alternating movements
Lesion in cerebellar hemisphere of frontal lobe

Inaccuracies in rapidly repeated movements (open and close mouth rapidly)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Intentional tremor

A

tremor arising when trying to perform a goal-directed movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dysarthria

A

Incoordination in the respiratory muscles, muscles of the larynx, etc.
Uneven speech strength and velocity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

lesions to the vestibulocerebellar pathway

A

Nystagmus- involuntary, rhythmical, repeated oscillations
of one or both eyes, in any or all directions of view

movement of the eyes minimises the ability to
focus the eyes on one point (fixation).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Effect of lesions in the spinocerebellar pathway

A

Gait ataxia (unsteadiness of walking), and disturbance of limb tone (hypotonia) and posture

17
Q

Cerebellar circuitary- inputs

A

Mossy fibres- [proprioceptive information] from spinal cord and brainstem

Climbing fibres- from inferior olivary nucleus

18
Q

Cerebellar circuitary- outputs

A
Deep cerebellar nuclei
To :
-Thalami
-Vestibular nuclei
-Red nucleus

(purkinje fibres inhibit DCN)

19
Q

Example of cerebellar circuit

A

One climbing fibre to each Purkinje cell, but with many synapses (divergence)

Many parallel fibres to each Purkinje cell, with one or a few synapses each
(convergence)

20
Q

Causes of Acquired Symmetrical Ataxia [5]

A
Alcohol
Metabolic (B12/Thyroid/Coeliac)
Drugs (eg phenytoin)
Degenerative (familial, MSA)
Immune (paraneoplastic)
21
Q

Vascular anatomy of the cerebellum

A

SCA and AICA branch from basilar

PICA branch from vertebrals

22
Q

Ideational Apraxia

A

damage to parietal cortex

Inability to report/plan a sequence of actions

23
Q

Ideomotor Apraxia

A

inability to use a tool on command despite being able to recall the sequence

  • Damage to supplementary motor area, premotor