L5 Anatomy Development Flashcards

1
Q

Septum transversum

A

Unsplit part of intraembryonic mesoderm which lies cranial to the pericardial cavity

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2
Q

is the cavity with in the embryo which developed by dividing the lateral plate mesoderm of the embryo

A

Intraembryonic coelom

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3
Q

lateral plate mesoderm of the embryo divides into

A

Somatopleuric mesoderm

Splanchnopleuric mesoderm

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4
Q

After head fold formation where is the location of the septum transversum?

A

Caudal to the pericardial cavity and ventral to the foregut

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5
Q

The pleural cavity, pericardial cavity and peritoneal cavities are the body cavities which are continuous with each other at one time of development, and develop into individual body cavities when?

A

With the development of the diaphragm

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6
Q

Shape of Intraembryonic coelom

A

Horseshoe shaped

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7
Q

What is the intraembryonic coelom divided into?

A

Pericardial coelom in the midline

Peritoneal coelom & pericardioperitoneal canals on either side.

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8
Q

Pericardial coelom

A

Pericardium

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9
Q

Peritoneal coelom

A

Peritoneum

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10
Q

Pericardio-peritoneal Canals

A

R & L pleural cavities

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11
Q

Where will the pleuroperitoneal membranes develop from?

A

The walls of the pericardioperitoneal canals

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12
Q

Development of diaphragm:

What will the pleuroperitoneal membranes do once they develop from the walls of the pericardioperitoneal canal?

A

Close the communication between the pericardioperitoneal canal and the peritoneal cavity

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13
Q

Foregut

A

Esophagus

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14
Q

suspended from dorsal body wall by its mesentery, which will also contributes for development of the diaphragm

A

Foregut/esophagus

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15
Q

closure of pericardioperitoneal canal by pleuro-peritoneal membrane

A

Development of the diaphragm

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16
Q

Development of the diaphragm

A

closure of pericardioperitoneal canal by pleuro-peritoneal membrane

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17
Q

Two structures that contribute in the development of the diaphragm:

A
  1. Septum transversum (Unsplit part of intraembryonic mesoderm)
  2. Dorsal mesentery of esophagus
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18
Q

Is the phrenic nerve a somite?

A

Yes

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19
Q

Where does the Peripheral part of the diaphragm develop from?

A

Body wall

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20
Q

Where does the Central Tendon of the diaphragm develop from?

A

Septum transversum

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21
Q

Exam q: Where does the posterolateral part of the diaphragm develop from?

A

Pleuroperitoneal Membrane

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22
Q

Where does the Crura of the Diapgragm develop from?

A

Dorsal Mesentery of Esophagus

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23
Q

Innervation Of The Diaphragm

A

Musculature (Motor) - Phrenic Nerve (C3,4,5)
Sensory- Centarl tendon and Major part of the Muscular part by Phrenic nerve
Peripheral part- Intercostal nerves

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24
Q

What develops with the development of pleuro-peritoneal membrane?

A

pericardio-peritoneal canal develops into pleural cavity. Developing lung grows into pleural cavity.

25
Q

Posterolateral defect of The Diaphragm

A
  • Due to failure of development of Pleuroperitoneal membrane
  • Congenital Diaphragmatic hernia
  • Pulmonary Hypoplasia
  • Life threatening breathing difficulties
  • One or both sides
26
Q

Eventration of The Diaphragm

A

eventration = herniation
Abdominal contents pushed through THIN posterolateral part of the diaphragm -which is developed from pleuroperitoneal membrane- (colon pushed into thoracic region)

27
Q

What is the laryngotracheal groove?

A

A small median groove that develops in the floor of the developing pharynx

28
Q

Exam q: Epithelial proliferation of Laryngotracheal groove give rise to

A

epithelium and glands of larynx, trachea, bronchi, and pulmonary epithelium

29
Q

Where does the larynx develop?

A

Larynx develops around the laryngotracheal groove.

30
Q

Lining Epithelium of the larynx

A

develops from endoderm of cranial end of laryngotracheal diverticulum

31
Q

Cartilage of larynx

A

4th and 6th arch (From Neural crest cells)

32
Q

Development of epiglottis

A

3rd and 4th arch

Caudal part of Hypobranchial eminence

33
Q

Laryngeal Muscles- develop from

A

4th and 6th arch

Nerve supply-Laryngeal branches of VAGUS nerve)

34
Q

Laryngeal atresia

A

Congenital high air way obstruction syndrome

35
Q

Development of Trachea

A

Trachea develops from the lagyngotracheal groove as respiratory diverticulum, which soon divides into left and right lung buds.

36
Q

Epithelium and Glands of trachea

A

Endodermal lining of larygotracheal tube

37
Q

Cartilage, Connective tissue, Muscles

A

Splanchnic mesesoderm

38
Q

Tracheal Stenosis and Atresia

A

Narrowing of trachea

39
Q

Tracheal Diverticulum

A

Out growth from trachea

“Pouch growth”

40
Q

Development of Bronchi and Lungs

A

Lung tissue develops from proliferation of the cells of lung buds at end of developing respiratory diverticulum.

41
Q

Epithelium and Glands of lungs

A

Endodermal lining of lung buds

42
Q

Cartilage, Connective tissue, Muscles of lungs

A

Splanchnic mesoderm

43
Q

Agenesis of lungs

A

Non development of lungs

44
Q

Lung Hypolasia

A

Reduced development of lungs

45
Q

Accessory lung

A

Due to additional branching from respiratory divierticulum

46
Q

Lobe of Azygos vein

A

Due to growth of lung tissue medial to azygos vein

47
Q

Congenital Lung Cyst

A

Closed sacs, due to separation of alveolar sac etc.

48
Q

Respiratory distress syndrome

A

Surfactant defeciency

49
Q

What are the 4 Lung developmental Periods?

A
  1. Pseudoglandular Period (5 – 17weeks)
  2. Canalicular Period (16- 25 weeks)
  3. Terminal sac Period (24 weeks – birth)
  4. Alveolar Period (Late fetal Period to child hood)
50
Q

1.Pseudoglandular Period (5 – 17weeks)

A
  • Lung resembles exocrine gland
  • Major elements are formed
  • Alveoli are not formed (Fetus born during this period fails to survive)
51
Q

2.Canalicular Period (16- 25 weeks)

A
  • Lumen of bronchi and terminal bronchiole increases
  • Becomes highly vascular
  • Alveolar ducts are formed
52
Q
  1. Terminal sac Period (24 weeks – birth)
A
  • Terminal sacs are formed
  • Capillaries bulge into alveoli
  • Intimate contact between epithelial and endothelial cells established
  • Type I (lining) and Type II (surfactant secretion) alveolar cells are formed
53
Q
  1. Alveolar Period (Late fetal Period to child hood)
A
  • Formation of alveoli
  • Exponential increase in surface of air blood barrier
  • 50 million alveoli in full-term, 300 million by eighth year.
54
Q

Floor of the Pharynx

A

4th Week

55
Q

Tracheoesophageal Fistula

A

Communication between trachea and esophagus

56
Q

Laryngotracheoesophageal cleft

A

Communication between larynx and trachea with osesophagus.
Air goes to the stomach and food goes to the lung leading to infection.
Intradabdominal P increases during birth.

57
Q

Lower respiratory tract

A

Larynx and below (larynx, trachea, primary bronchi and lungs)

58
Q

Lung tissue develops from

A

proliferation of the cells of lung buds at end of developing respiratory diverticulum.

59
Q

respiratory diverticulum divides into

A

left and right lung buds