L4 - pH and buffering Flashcards
1
Q
what is blood pH
A
narrow range (7.35 to 7.45)
living range is 7-7.8
2
Q
what is acidosis
A
low blood pH
3
Q
what is alkalosis
A
high blood pH
4
Q
where do we get our acids from?
A
-diet
- generated by metabolism:
1. breakdown of proteins
2. incomplete oxidation of fats or glucose
3. loading and transport of carbon dioxide in the blood
5
Q
what do buffers do
A
buffers resist abrupt and large swings in the pH of body fluids by
- releasing Hydrogen ions when the pH begins to rise
-binding Hydrogen ions when the pH drops
6
Q
concentration of water
A
55.6 M
7
Q
what is the pKa
A
minus the log of the dissociation constant.
pH value at with the acid is half dissociated.
8
Q
what is the importance of the pKa
A
tells us the pH where the tested acid can act as a buffer
9
Q
oxyhemoglobin pKa
A
6,8
10
Q
A
