L35: de novo FA and TAG synthesis Flashcards
1
Q
When is lipogenesis active and where does it take place?
A
de novo Lipogenesis is active in the fed state (a high I/G, absorptive phase).
- Lipogenesis occurs mostly in the liver. Ironically, only small amounts of de novo lipogenesis occur in adipose tissue.
- Cellular location: lipogenesis occurs in the cytosol on the surface of the SER (smooth endoplasmic reticulum).
- The purpose of lipogenesis is to store energy in the form of triacylglycerol, and to supply membrane lipids
