L31: Hypersensitivity and autoimmunity

Question 1

4 common sites of allergic reactions?

Answer 1

respiratory:
allergic rhinitis
sinusitis
conjunctivitis
asthma

skin

gut- diarrhoea, cramps and vomiting

multplie organs - anaphylaxis

Question 2

treatment options for allergies?

Answer 2

avoidance

antihisatamine

corticosteroids

sodium cromoglycate- stabalise mast cells

sympathomimetics- epinephrine

desensitisation - gradually increase allergne dose to build tolerance

Question 3

what is the type I immune hypersensitivity reaction?

Answer 3

IgE mediated allergic or anaphylactic response

- immediate

Question 4

what is type II hypersensitivity?

Answer 4

antibody mediated cellular cytotoxicity

• also complement activation
• frustrated phagocytosis